Metastases Bone.

Enye yeengxaki ezinkulu zonke umhlaza - kokuqala kunqandwa kweqonga yokugcina - ibakala Ukudlulela. Ukudlulela nakujoliso olutsha na neoplasms amabi, ukuba eyayinethombo nkovu okanye igazi ibhalwe amalungu kude nezihlunu, apho uqala ukuphuhlisa inkqubo neoplastic.

Umhlaza phantse onke amalungu nezihlunu ukuze iyakhula namathambo. izilonda inokufumaneka phantse kuzo naziphi na izakhiwo ithambo. Eyona njalo - metastases apha emqolo, ubuncinane kwi isinqe, iimbambo omzimba.

Yintoni yamathumba iyakhula nethambo?

Amaninzi, le nkqubo kwenzeka xa lo, lengqula umhlaza nobubovu wesinye mammary namadlala.

Kukho iindidi ezimbini ezisisiseko yenkqubo zophendlo lwezifo kwi ithambo - osteoblastic kunye osteolytic metatstazirovanie. Kuba yokuqala ifomu itywina ekuso esiqwini wethambo, abakwicandelo ingakumbi kwizimbiwa yayo. Ifom yesibini inceda "ukuhlamba ngaphandle" izimbiwa, nto leyo ekugqibeleni ubandakanya ukuxozwa kunye waphuka.

Le Pathogenesis kwesi sifo kukuba ekhuthaza iiseli ithumba. Ukuba Ukudlulela somhlaza ibandakanya osteoblasts kwinkqubo ye - ukuphuhlisa ifomu osteoblastic. Xa ithumba yokuqala esendleleni yazo edibana ithambo resorbing iiseli (osteoclasts) - yeyona ukuyilwa metastases osteolysis.

Kwiimeko ezininzi, imbonakalo metastases kwi ithambo ebangela intlungu yokugqibela. Iintlungu syndrome kubangelwa ngumonakalo kwalapho neziqu ithumba, ukunyuka koxinzelelo ngaphakathi ithambo, yaye ngenxa neziphelo eku- of luvo eyabelwe izinto Ukudlulela. Ukongeza, iintlungu kwenzeka xa kwamathambo okubangelwa olindelwe zokupasa zokugqibela (uphawu iifom osteolytic). Ukuze zenze osteoblastic hypercalcemia uphawu kubonakaliswa (calcium lwegazi).

Ingozi kuziphuko yindlela aphezulu iingxaki - Embolism yemiphunga, enzulu thromboembolism umthambo (ekugqibeleni, oku kukhokelela kwilahleko ezisebenzayo ukulayisha omzimba okanye lomzimba kunye nokusebenza).

metastases Bone abafunyenwe usebenzisa X-ray. Ukulungiselela le njongo, sebenzisa ray okucacileyo kwi ubuninzi izilonda kuwenza, kwakunye uhlobo osteolytic. Kwimeko osteoblastic wathwala scan radionuclide. Enye yeendlela yokuchonga, apho ingabonwa kuphela metastases ithambo, kodwa kwezinye Amalungu nezihlunu - PET 18P-deoxyglucose.

unyango zoqhaqho metastases bone kuboniswe ezinjengokwaphuka yokugqibela kunokwenzeka. Ugqirha wamathambo wenziwa utyando ukomeleza ithambo ngu nezikhonkwane ngokufaka kunye ekubalekeleni kunye ithumba lwesamente ithambo.

Radiation therapy kwi umthamo malunga neshumi elinesihlanu - amabini anesihlanu wulwe (kungayanyaniswa amaqhezu ezine), isiqingatha izigulane ukunyamalala intlungu. Ithamo amathathu - amane anesihlanu wulwe ebangela ukuphucuka okukhulu imeko yomguli, ingakumbi ezo ukuphuculwa lwakhula sesichengeni elandelayo for two - iiveki ezintathu.

Umdlalo wesibini emva konyango imitha, ngaba ukusetyenziswa kwiteksti eqhumayo. Ngoku ngokubanzi kusetyenziswa unyango bisphosphonate. Le asidi ezizodwa zinqanda umsebenzi osteoclasts. Ukongeza, la machiza buthathaka ubuzaza intlungu kwizaphuko amathambo, kwakunye luphuhliso yamathumba.

Ngoko ke, abantu abane ukuba Ukudlulela ukuba ithambo zinokuba nomahluko, ngokuxhomekeke kwasendaweni of osteblastnoy okanye osteolytic iintlobo kunye neendlela zonyango.