Iivithamini Found ukuba sandise ubomi obuphilwa

Ngoxa eshumayela ukhangelo nempumelelo lichiza ukungafi kancinane ngaphambi kwexesha, kodwa impumelelo ebalulekileyo kwiinzame yokuphelisa ukufa kunye ukwaluphala kufikelelwe kuzo. Ngokutsho isifundo esitsha epapashwe kwiphephancwadi Science, vitamin othi nicotinamide riboside (NO) uphelelwe ukukwazi ukukhuthaza ngokutsha esiqwini kwezihlunu neempuku abadala, ngelixa sisenyusa sempilo sabo.

Ukuthetha ngale idabi esibonakalayo, umphandi elikhokelayo uJohan Averks wachaza ukuba amayeza okungenisa uyakwazi ukufumana iinzuzo ebalulekileyo kulo msebenzi. Uthi ukuba ngenye imini ngoncedo izongezo zokutya, singenza ngaphandle uqhaqho.

Ukukwazi ukuntshula

Njengazo zonke ezinye izilwanyana, phezu ubomi umntu ngcembe ulahlekelwa iiseli ngenxa ukwaluphala. Le nkqubo kwakhona eyaziwa ngokuba ukufa kweeseli. Kodwa kunokuba kufa nje, umzimba wethu zivuselela unikezelo yayo, ukukhuthaza uphuhliso iiseli stem.

Noko ke, ngenxa yohlobo yethu yasemhlabeni kukuba ekuhambeni kwexesha, lo ukukwazi ukuntshula ebizwa ngokuba yimetabolism isenokucotha, uze ekugqibeleni kukhokelela kokufa komzimba. Izazinzulu zinomdla, ukuze wandise ubomi babantu. Ngoko ke, ukuba sihlala sifuna iindlela ukuqala ngokukhawuleza inkqubo yokubuyisa ixesha ekuphulukenwe nalo ngokukhawuleza kokuba iqale isantya phantsi. Ngoku Iqela wabaphandi banokugqiba ubuncinane enye isiziba kwiphazili.

Yintoni imfihlelo mitochondria?

Ngokutsho iqela izazinzulu, isitshixo ifihlwe mitochondria zethu, nto leyo kudla ngokubizwa ngokuba "izityalo amandla" iiseli zethu. Ezi organelles ezincinane ukujikelezisa amandla ezifunekayo uluhlu olubanzi iinkqubo cellular. Uphuhliso iiseli ezikhethekileyo isiqu, umzekelo, kuxhomekeke amandla efunyenwe kwi-mitochondria.

Kuye kwafunyaniswa ukuba kwekhono ayo yenye imiqondiso yokwaluphala. Ngoko ke, ababhali isifundo ndagqiba kwelokuba ndifune unxulumano ngqo phakathi le kwekhono kunye nokukwazi iseli ukuba ukuntshula, enethemba ukufumana indlela ukubuyisela ngayo.

Xa iiseli stem ukuphuhlisa, zisebenzisa isitokhwe obizwa compound nicotinamide adenine dinucleotide (nad +). Lidlala indima ebalulekileyo ekuqinisekiseni eqhelekileyo yokusebenza mitochondria. Ngoko ke abaphandi esigqibeni sokuba liqalise neempuku endala NR, nto leyo njengomanduleli nad +, ukuze abone ukuba kuya kuba nawuphi umphumo ubuchule babo ukuphinda uvelise iiseli kwezihlunu.

iziphumo zophononongo

Iziphumo zabonisa ukuba emva ulawulo NR, iimpuku bakwazi ukwenza inani elikhulu leeseli izihlunu stem ukuba kamva zikhule zibe ziiseli kwezihlunu abadala, ukwandisa ukunyamezela kwabo kunye nokusebenza. Ngokomzekelo, kungekudala bakwazi ukusebenza ixesha elide aze abe oluzinzileyo ngakumbi.

Iimpuku ukuphathwa NR, nabo baphila ixesha elide ngaphezu kwabo bangazange bafumane vitamin, efana kakhulu _kwi-3. Kuyaphawuleka ukuba ababhali phando akazange phendla naziphi na iziphumo ebezingalindelekanga ezibi naxa yayisalawulwa amathamo eziphakamileyo NR.

Kakade ke, umsebenzi kufuneka okungakumbi ngaphambi niphikisana ukuba izazinzulu baye bakwazi ukuphuhlisa unyango. Ngapha koko, loo nto, kodwa bengazi ukuba luyasebenza na okanye lukhuselekile, le vitamin zingasetyenziswa ekunyangeni zokuguga ebantwini.