Monocytes yegazi eyonyukileyo: njengoko kungqinwa uhlalutyo

Sonke amaxesha ukudibana ixesha amagama abangenagama. Ekubeni ICBC Kwathi yonke into, kusoloko kukho umbuzo umbuzo, yintoni na monocytes, bangaphi kubo kufuneka egazini, yaye njengoko kungqinwa ixabiso inokufumaneka xa monocytes igazi zandile?

Monocytes - zinkulu ubukhulu iiseli ezibomvu, ukubayinxalenye iklasi iiseli ezimhlophe zegazi. Ngokutsho isakhiwo - iiseli okweqanda kunye ingxenye enkulu kunye nokungabikho iinkozo kukho icytoplasm (agranulocytes) nokuphendula iinkqubo ukudumba kwinto emzimbeni egazini labo. Yimeko apho monocytes igazi ephakeme, ebizwa monocytosis.

Ezi seli akhiwa ngayo umongo wethambo of monoblastov, ngoxa singahlukaniswa meiosis, kwaye kwiintsuku ezimbalwa kamva abasuka egazini ancedisana, kunye phaya kwinqanaba yeselula ababandakanyekayo phagocytosis. Kwiimeko ezininzi, le nkqubo wazibona ukuphendula ukuya kwii-zokosuleleka xa monocytes macrophage sele abaqhagamshelwe ukugcina umzimba ekwathintela iiproteni amazwe ukwenza iantigens-unalo udibaniso. Xa inkqubo phagocytosis of monocytes bangabi kutshatyalaliswa, njengoko kudla ngokwenzeka kunye eosinophils kunye neutrophils, kodwa zakha umngxuma esicacisa site komtshiso oko. Eyona Uphawu kuyafana yokuziphatha ezi seli kwiindawo emuncu.

Monocyte iqulethe inani elikhulu lysosomes, leyo sikwetyise izinto iseli fagotsitiruemye sisusa site sisilonda esidumbileyoesingaphakathi kunye nokulungiselela ukuze ngokutsha. Ikakhulu monocytes egazini, ngaba ngokukhulu ezisegumbini udakada, iindawo nkovu kunye lomongo wethambo, ngoko ke konzakale omnye kubo kuya kuncipha monocytes. Monocytosis awasiwisayo yamathumba yingozi, izifo ezosulelayo (negcushuwa, tuberculosis), izifo zenkqubo (lupus zomzimba, izifo igazi), collagenosis, granulomatosis.

Okubhalwe kwezi leukocytes mononuclear egazini yesiqhelo peripheral - hayi ngaphezulu kwe 0.03 - 1.00 × 109 / L, kunye nemali yabo bebonke kufuneka ingadluli 8-10% kwezi leukocytes zizonke. Ukuba monocytes ngaphezu lo mmiselo, eli thuba ukudlulisa iimvavanyo ezongezelelweyo ukuchonga umthombo yosulelo kwaye unyango olufanelekileyo. Monocytes zibe ukusebenza cytotoxic (kungaba yingozi iiseli ithumba ngokunjalo izifo ezifana seengcongconi), bavelise iikhompawundi asebenzayo (IFN), bazibandakanye ingqalelo arhente zasemzini.

Nokuba monocytes igazi bukhulile, akunakwenzeka ukuba uchaze ngokuchanekileyo umfanekiso axelwe zenkqubo kwiintetho ezikralayo, okusekelwe kuphela Izalathi zazo oluninzi. Ukulungiselela le njongo sithekelela lilonke leukocyte formula negazi; ukuba oluninzi monocytes, kunye nokwanda kwenani lymphocyte kunye, kwaye inani elifanayo eosinophils, kodwa ke inani umxholo T-lymphocyte, oko kuthathwa njenge isizathu yabaneziphumo ezihle imeko zophendlo lwezifo. Mu kuya kwa nshita urhulumente apho monocytes yegazi eyonyukileyo njengoko inani neutrophil leukocyte shift ekhohlo, kwaye ngaxeshanye ukuncipha kwenani eosinophils kunye T-lymphocyte.

Ukuba ukuhla okukhulu kwinani monocytes elifana neli egazini, ngoko oko kuza ku zikarhulumente ezifana monocytopenia (monotsitopeniya). Lo mfanekiso iqatshelwe egazini ithambo izitshanguba ezinomongo, xa gemapoeza inkqubo agxojiweyo zizifo nolahlo ngokubanzi ubovu, izifo igazi, iziyobisi hormone, iimeko uxinezeleko kunye nomothuko, ekubelekeni kunye utyando, kwakunye imizimba ukwenzakala apho zisekelwe monocytes. Kwimeko inani monocytes egazini peripheral kuyimfuneko ukuqhuba uvavanyo lwegazi yesibini. Ngenxa yesi sizathu, kuya kuthunyelwa ke unyango ohambelana entsonkothileyo kwesi sifo ngxabano. Ekubeni monocytes baphendule ubukho zokugula emzimbeni, oko kuchazwe kakuhle ukuba eyona nto iya kuba unyango zintsholongwane kunye unyango nomqondiso.