Pseudomyxoma peritoneum: Oonobangela, Iimpawu, diagnosis and Treatment

Pseudomyxoma peritoneum i ngezifo oko luphawu zokwanda yencindi, ekugqibeleni bajamelene kuhlela.

Kuthetha ukuthini?

A elithi livele zesayensi ukuba Werth ngo-1884. Ekuqaleni isicelo amatyala izilonda zasesekondari, cysts yavusa nhlanganiso. Ekuhambeni kwexesha, siye safumanisa ukuba pseudomyxoma peritoneum ibangela ukufuduka em- izinto ezifumaneka isihlomelo, nto leyo, evusa a flow wokuchama intuthuko okanye nenyongo.

Izazinzulu ziye zafumanisa ukuba amazwe yencindi kungenxa breaks ezizenzekelayo xa zolule ngokugqithisileyo okanye ukunciphisa balo babulingana nesandla eludongeni, kwakunye ungenelelo ngotyando: ukususa i cyst okanye isihlomelo.

Ngaphantsi neemicroscope?

Xa sifunda lweHo- kwi sikrini eliphezulu kunokuthi kubonwe ukuba pseudomyxoma peritoneum ezele serous into yokuqala, apho ukungenelela yencindi yomlomo. Oku ekwenyukeni nangokurhala, ngenxa apho iindonga deformation kwenzeka:

• ukuqina;
• yamanzi;
• nemibimbi.

Kwezinye iimeko, umphezulu uba velvet-like, ngoxa kwezinye iindawo kukho legazi. Xa uphuhliso leengxaki kwenzeka ngelotha kweziporo isisu, omentum kunye isisu. Bodies balahlekelwe kuyimfuneko eqhelekileyo yokusebenza ukuhamba.

Ukufunda le ndawo ochaphazelekayo ngemicroscope, ungabona ukuba iiseli apho yencindi kukho umaleko ngelaphu, inxalenye apho kukho nokungena. Epithelium kule seli elungisiweyo ingaba:

• cubic;
• atshabalalisa.

Ukubunjwa ekugqibeleni iiseli isifo ochaphazelekayo iyatshintsha, oko kumiselwa ibakala esi sifo. Xa lokufunyaniswa "pseudomyxoma peritoneum" iiseli yencindi kuvela:

• lymphocyte;
• fibroblasts;
• iingxilimbela multi-core;
• leukocytes polymorphic;
• histiocytes;
• epithelium columnar.

Le ndlela yokugqibela ingenisa kule peritoneum. Utyhutyha emzimbeni kuyo ngokusebenzisa perforation. Kungenxa kunyebeleziso le epithelium, kwaye zifakiwe kudidi lwe neoplastic peritoneum izifo pseudomyxoma, ogama iimpawu ezicacileyo ngokubanzi. Le nkqubo iqhubeke sluggishly, zixhaswa yencindi, uthathwa ukuba arhabaxa.

A Ithumba - its kuyoyikisa?

Yamathumba cell peritoneum kweentlobo ezimbini:

• eziziiprayimari;
• zamabanga aphakamileyo.

Yeyeza ebulalayo rhoqo alimise kuyo kuwenza, oko kukuthi aphakamileyo. Njengoko kuba zaseprayimari, ngoko kuzo sinobuso peritoneum pseudomyxoma. Iimpawu zesi sifo okokuqala, oko ungenakubonwa. Ngophuhliso iiseli izifo kwenzeka phezu peritoneal ngaphandle kokuchaphazela amalungu ezikufutshane. Lo ngumsebenzi ndoqo umhlaza ezichazwe. Indlela iiseli ezosulelwe andise - kwentamo.

Xa kunjalo, ngaphandle xa ndlala nqa kunye nezinye nelaphu, bathi kwafunyaniswa ukuba pseudomyxoma peritoneum, nto ngumlomo elingamncediyo. Oku kubangelwa ubukhulu becala ngenxa yenyaniso yokuba ngezifo lidla kubonakele ngasemva lomhlaza esele waphawula ngaphambili namanye amalungu.

ekuxilongweni

Uxilongo "pseudomyxoma peritoneum" lidla ukubekwa laparotomy. Yabela ngayo ezi mpawu zilandelayo:

• neentlungu esiswini (idla buthuntu);
• ukwandisa umthamo esiswini ngenxa ngaphandle kwesizathu.

Oku kwenzeka ngenxa yokuba nokwanda kwi nezihlunu ulwelo lomzimba.

ihloniphekile:

• umonakalo kuphela;
• psevdomiksoglobulez.

Yenzeka njani le nto?

Ngokuqhelekileyo, esi sifo kubonakala le komsipha ngasemva cyst kulo. Oku kungenxa yokuba nhlanganiso into ukungena kulo kwisisu, hayi anodaka kuphela, kodwa ke epithelium. iiseli zakhe abakwazi ekhethekileyo ukuba ingenisa esikule abazifumana bekuzo. Ekuhambeni kwexesha, amaziko angcakacileyo kwakhona ukuqalisa ukuvelisa yencindi yomlomo.

Ngokuqhelekileyo, lokufunyaniswa "pseudomyxoma peritoneum" kuthetha ukuba isifo olubulalayo. Pathology basonta kumphezulu, musa kukhokelela nokwaphulwa nokusebenza kwamalungu kunye neenkqubo zangaphakathi. Pseudomyxoma mobile, kuba zibandakanya "ukungcangcazela syndrome". Namhlanje, indlela kuphela olusebenzayo zokufumanis isifo - utyando apho iisampuli zeethishu ifunyenwe. ngezifo yesiqinisekiso inikwa ngumntu biopsy.

Yintoni ukuba ulindele?

Kufuneka ube uzimisele ukuqinisekisa ukuba uxilongo "pseudomyxoma peritoneum" unyango - uqhaqho. Enye indlela ephumelelayo yokulwa ngezifo kodwa yasungulwa wayengekho. Ukuba ithumba nabungozi, kuya kufuneka ukuba ukuyinqumla, enikwe apho izicwili ndisesempilweni.

Xa isifo angakwazi kufumana nje amathuba amabi, nje unyango, abakulungeleyo ukuya ukususwa olukhulu. I-ALS elingamncediyo. recovery elipheleleyo enokulindelwa kwimeko ithumba nabungozi kule nkqubo, kodwa emva ngokutsha sikhulu uqhaqho akanako ukuvala ngokupheleleyo iinkqubo zemveliso kunye nokwanda kwe ngebhitumene.

Oogqirha ayisoloko nako ukufumanisa ngokuchanekileyo ukuba kukho yayisele yobubi. Oku ubonakaliswa isifundo histological, nto leyo kubonisa ukungabikho iiseli zomhlaza kwisampulu lolwabo kuthinjwa, kodwa ayikwazi ukukhonza njengesiqinisekiso ukuba umzimba akukho namnye konke konke.

Xa unyango uxilongo "pseudomyxoma peritoneum" kukhethiwe, sigqibe ukuba Ithumba sele yobubi. Oku kungenxa frequency eliphezulu likakade, ukuhlasela.

Yintoni ukwenza ntoni?

Phambi kokuba uqonde ukuba yintoni na uxilongo "pseudomyxoma peritoneum" (isigaba sokugqibela) iimpawu zesifo, umele kuqala ukucacisa, unyango radiation nemichiza wabonisa nokungasebenzi kumlo ochasene nesifo.

Ngelo xesha langoku, hayi wasungula isipho esikhethekileyo esi sifo. Nje yencindi nokususa wabonisa yayingaphelele kuba iiseli ukungena epithelium, qhubeka sivelise.

Kukholeleka ukuba iziphumo ezilungileyo enokwen- radiotherapy, xa kukho ukungakhuseleki ancedisana enikuvayo platinum, izinto ezineeathom ezilinganayo igolide.

Ngaphandle unyango oluchanekileyo onesibetho esifa kwisithuba seminyaka omnye okanye emibini. Kwezinye iimeko, esi sifo kunye fistula eluswini.

bokuqonda ezibaluleke

Amanani bathi pseudomyxoma peritoneum kwenzeka ngo-1% yezigulane, ke ngoko, loo nto ithathwa njengokuba ezinqabe kakhulu. ingozi wayo enabela ezifihlakeleyo, uphuhliso Nedlac, nabanye abantu abane kakuhle.

Kwezinye iimeko, uphuhliso leengxaki kwalelo mucin appendicular. Phakathi iimpawu lidiza of Oncology - namathumbu kokuphazanyiswa.

Isifo luphawulwa ntlobo zilandelayo mucin:

• Free.
• Imali. Bekela bucala elikhulu, encinane. Yokuba kufanelekile pretty ngokuqinileyo ukuya kumphezulu peritoneal. Iidipozithi kwenzeka kwiinkqubo ukudumba kwaye iiseli akhoyo mesothelial. Kwezinye iimeko, kukho fibroblasts, emithanjeni. Kodwa iiseli non-zeplastiki kwiimeko ezininzi akafumaneki.
• Amachibi. Ezi izihlwele ngokubanzi awafuneki iqokobhe kollagenizovannuyu. Kwimfundo inzululwazi, ezifana oqhekeza mucin.

Bani ukuba ningakholwa?

Kwiminyaka yakutshanje, kwizibhedlele eziliqela Israeli ukuqinisekisa unyango epheleleyo zomhlaza. Ngokuqhelekileyo, imibutho efana musa ukunika nayiphi na izithembiso ezisemthethweni, kodwa iintengiso esimnandi, enika ithemba kwizigulane kunye nezalamane zabo.

Khumbula ukuba kufuneka ukhethe amaziko onyango, ngaphambili akuba safunda ngenyameko amaxwebhu, kwakunye neempendulo abo okunene baya khona unyango. Lumkela oogqirha ezingenalusini ngenkonzo engekho.