Kubola kwiMfazwe yeHlabathi yokuQala ukunceda ukumelana iintsholongwane olwa-resistant

Trypaflavine - yinto kubola, eyasetyenziswa ngokubanzi ekuqaleni kwenkulungwane lokugqibela. Ngenxa kwafunyanwa penicillin yayekwa, kodwa ngoku kukunceda ukusombulula ingxaki sokwanda iintsholongwane zintsholongwane-resistant, adla kuwo superbugs. Nangaphezulu Akumangalisi, trypaflavine, kuyabonakala ukuba kwandisa omzimba ukuba iintsholongwane, ekukhuseleni evela abandayo, kunye nezifo mhlawumbi kakhulu ngakumbi wentsholongwane egazini.

Ukuvulwa-nzulu German

-Nzulu German omkhulu Paul 'uErich ngo-1912 lwafumanisa ukuba Acriflavinium chloride, eyaziwa ngokuba trypaflavine esinganyanga ezinye izifo xa isicelo nolusu. Kuye ezisetyenziselwa ukunyanga belele yokugula e-Afrika ekumazantsi eSahara, ukwenzela ukuthintela usulelo lwe amanxeba ngethuba leMfazwe yokuQala yeHlabathi, kwaye nkqu efakwa nxamnye: ukuvuza ngaphantsi.

uphando lwakutshanje

UGqr Michael Ganter of the Hudson Institute Australia for Research Medical ikholelwa ukuba eli ziko usenalo ilungelo lokuba khona, ngokubonelela enye indlela yokujongana iintsholongwane ukuba ziye ukumelana nemithi ezisetyenziswa ngokuqhelekileyo. Ganter nguye umbhali abaphezulu zesifundo, leyo bubungqina bokuba iingedosi ezincinane kakhulu trypaflavine ukhuthaze inkqubo omzimba kwizisele cultured, ukuphucula ubuchule babo ukulwa kwamagciwane.

"Siye ziboniswa okwesihlandlo sokuqala trypaflavine ngokuzibophelela kwi DNA zeselula, ungayenza naphi amajoni omzimba, ebangela impendulo ongqingqwa kuluhlu ezinokuba ezibanzi iintsholongwane," - Ganter uthe kwingxelo.

Umbhali uGqr Pepin Zhenevera of the Hudson Institute wongezelela: "Uphando lwethu lubonisa ukuba trypaflavine ivuselela amajoni omzimba yabantu kunokuba nje yokubulala iintsholongwane. Wavele, oku kuthetha ukuba le ntsholongwane iya akayi inokuzitshintsha kwaye abanganyangekiyo ichiza. Ngoko trypaflavine inokuba enye abanesakhono antibiotics ezikhoyo. "

Nangaphezulu Akumangalisi, ukunyuka okukwazi kudlulela ekulweni iintsholongwane. Ganter bakhe intsebenziswano-ababhali ukuphakamisa njengento intsholongwane umzekelo herpes, apho trypaflavine kunokuba luncedo kuba linokusetyenziswa on-site flash kanye njengoko kwenziwe ngaphambili amanxeba.

ubukho bokusetyenziswa

Trypaflavine kuthetha bunetyhefu xa tapeworm kwi wokugaya kunye neenkqubo zemiphunga umzimba, kodwa Ganter uthi ukwanda sifo, kubonakala ngathi, uyabonakala xa amathamo ukuba eziphantsi kakhulu ngaphezu kwabo ayakwazi bahambe umonakalo. Ngenxa yoko, wayeba, kunokwenzeka ukuba ukusebenzisa inhaler ngeempumlo ukunikezela igcuntswana leyeza beziyobisi iiseli isifo ngeempumlo kwaye ukukhanya ukuba babulale usuleleko eliphezulu zemiphunga. Uya kuba nako ukukhusela nxamnye iintsholongwane ezibandayo, nkqu ndisindise ubomi xa kuthe kwakho kukho ukuqhambuka ezifana SARS.

Trypaflavine ubonakala ishiywe zisetyenziswe kulawulo efakwa kuba ichiza kuhlala egazini ngumsinga ixesha elifutshane. Nakuba kunjalo, isiphumo sayo ixesha elide xa lisetyenziswa eluswini, kwaye Ganter akrokrela ukuba baya kuba lokwenyaniso iphecana yokuphefumla, nangona ulingo lwezonyango azikhange kuqhutywa.

Imvuselelo trypaflavine kusenokuba kubangelwa kwi Internet, ekubeni imisebenzi German zenzululwazi zenkulungwane yama-20, ngoku ifumaneka lula kubaphandi ehlabathini jikelele, kwaye zinika isikhokelo luncedo kakhulu eenzululwazi mihla.