Ezigula multiple

ezigula Multiple (disease Rustitskogo Clair) namnye ngaphandle ithumba lomongo wethambo, nto leyo ubunjwe iiseli plasma lokuvuthwa ezahlukeneyo. Inkcazelo sifo sasikhona kwinkulungwane XIX. Ngokusisiseko, esi sifo lixhomekeke inxalenye omdala abantu kunye nabantu abadala.

Kukholelwa ukuba ngesiphumo ezigula ezininzi ziye kwezo ze B-lymphocyte. Esi sifo ukwanda zophendlo lwezifo weeseli plasma, nto leyo ekhokelela kokutshatyalaliswa lwesiyobisi ithambo nembubhiso ithambo. Ngenxa yoko lweenkqubo, yamophula rhoqo uze utshintshe isimo sabo. Bakhulela amanani amakhulu, iiseli plasma ukuvelisa paraprotein, ebangela ukwanda protein egazini. Hyperproteinemia kubangela isifo sezintso kunye nophuhliso izenzakalo ukusilela kwezintso. Ukubeka bucala kwi tubules, paraprotein ibangela nefrogidroz kunye amyloidosis.
Ukuqhubela phambili le sifo kukhokelela utshintsho zophendlo lwezifo egazini, hematopoiesis kakuhle. Kulo mfanekiso uyakwazi ukubona anaemia igazi, zegazi eliphantsi iiseli ezimhlophe zegazi.

kubonakaliswa sifo

ezigula Multiple asilo xesha elide uzenza waziva, kwaye imeko yomguli kunokuba eyanelisayo kakhulu. Kweli xesha lokuqala sifo kubonakala oluthile, ukudinwa, asthenia. Ngokuqhelekileyo, uphawu lokuqala olwenza ukuba ukubona ugqirha, i intlungu ezisezantsi emva, ngomqolo namathambo, iintlungu kuyaphela ukwandisa. Iimpawu engaphezulu ezinxulumene hematopoiesis kakuhle (anemia, thrombocytopenia), ukuphuhlisa ukopha syndrome, kwanangezibilini engabalulekanga, thromboses. Phakathi kwezi mpawu nezifo ezinxulumene ne ukwandisa insufficiency kwezintso kunye Hyperproteinemia.

ekuxilongweni

Kweli xesha lokuqala kukho ukwanda egazini erythrocyte izinga neentlenge ukuba umphumela dysproteinemia. Kunye ukuqhubela phambili le nkqubo kubonakala anaemia, ukuncipha neeplatelets kunye leukocytes. Ekuhlalutyeni ilahleko umchamo protini waphawula enkulu. Xa uhlalutyo zengqo- inxalenye yegazi kumiselwa ukwanda protini iyonke. Zikhala ukusilela kwezintso - ukwanda creatinine kunye urea, electrolyte ukungalingani.
Lokufunyaniswa "ezigula multiple" imiswe isekelwe phezu ngenxa yokuba uhlalutyo kweeseli umongo wethambo. Le misebenzi iphambili diagnostic. indlela msizi ukwenza X-ray ithambo zokubhaqa iziphene kunye sengozini ithambo, izilonda kwamathambo. Uyacetyiswa ukuba baqhube proteinogram.

Unyango lwe ezigula Multiple

Ukuba uhlolo wafumana ezigula, unyango lwesi sifo ukuza kuthi ga ngoku - ingxaki ingasonjululwanga. Kufuneka uqaphele ubude bobomi kwizigulane kunye unyango ekunene kwaye ikhosi tyaba esi sifo kukuba kwiminyaka emihlanu. Uthomalaliso kwesi sifo kusebenza imithi leyo anqanda uphuhliso ithumba (cytostatics). Kodwa ke la machiza kongeza kuphela ubomi kwizigulane. Ekuqaleni unyango lwabo kumiselwe ngeedosi bothukile, emva kokugqiba le utshintshe nje khosi kuthomalaliso yesondlo.

"Prednisolone" lisetyenziswa xa zidityaniswe kunye neziyobisi cytotoxic. ukusetyenziswa kwayo abangaphangeliyo ukutshatyalaliswa ithambo kwaye nemiphumo emihle kunye nokwanda calcium. Iirejimeni ngophuhliso eziquka zizifundo ezininzi iziyobisi, ngeedosi ezahlukeneyo ngokuxhomekeke ebukhulwini kunye nohlobo ezigula. Iziphumo zonyango kuvavanywa emva kweenyanga ezintathu emva kokuqalisa kusetyenziswe amachiza.

Phezu umbusi, ukusilela kwezintso, linokufuna ihaemodialysis inkqubo yonyango.

Mhlawumbi ukusebenzisa unyango radiation. Oku kumiselwe ukuba unyango lweendawo ithumba encinane ibekwe amathambo kunye kwizihlunu ezithambileyo.