"Buspirone": ncomo, imiyalelo ukusetyenziswa, analogs

"Buspirone" libhekisela mali ibe nempembelelo luvo. Kuyinto anxiolytic, eyenzelwe ukuphelisa ixhala kunye noloyiko, kuqheleke bubuthongo, ukuphucula kwintlalontle phambi neurosis. Tablets "Buspirone" ezinye Izimo, kwaye kunokubangela iziphumo ezingalindelekanga.

Ukubunjwa kunye nokumila "Buspirone" iziyobisi

Ichiza ifumaneka azipilisi kwindawo umthamo mg-5, 10 no-20. Le into chiza esebenzayo - buspirone. izinto zoncediso ziquka potassium hayidroksayidi, umbona starch, wemagniziyam stearate.

imiphumela kwemithi

Yintshukumo umthomalalisi iziyobisi, anxiolytic. Iyeza lisusa iimpawu yokoyika kwezityalo kunye nempilo yengqondo. kuthetha indlela yokusebenza nokuyiqonda, kodwa kuyaziwa ukuba "Buspirone" yahlukile benzodiazepines kunye namanye amachiza ukusebenza anxiolytic.

A ukusebenza ngamandla inhibitory kwi-CNS emva kokufumana "buspirone" amacwecwe ngaphandle kweintanethi. Imiyalelo yokusebenzisa ibonisa ukuba ichiza kunciphisa ukusekwa kunye nokukhululwa serotonin, ukucola serotonergic, ikhuthaza kuthintele dopamine D2-receptors (ezinjengeetheminali postsynaptic kwaye presynaptic), ibalekisa excitation zemithambo-luvo dopamine ise-ephakathi. Emva kokuba ukupheliswa ichiza hayi kuvandlakanywa kukuvela iimpawu ukurhoxiswa abuyele nexhala.

Ichiza ilungiselelwe yolawulo ngomlomo. Zingene emzimbeni ixesha elifutshane ixesha ako ngokupheleleyo lokugaya. Ngenxa yoko, ukutya ebanzi bioavailability yi-4% kuphela. Inqanaba eliphezulu beziyobisi egazini kuphunyelelwa malunga neyure emva ukungena kwisiqwenga zesisu. Half-ubomi yenziwa iiyure 2-3, nangokuzikhanyeza iiproteni plasma ingqamana 95%. ukusetyenziswa "buspirone" Continuous awuchaphazeli ukusebenza kwayo.

Ngexesha unyango, musa nje ukuba i "Buspirone" kuthetha isiphumo. Imiyalelo yokusebenzisa ibonisa ukuba ukusebenza ichiza kwixesha ukususela ngomhla wesi-7 ukuya kusuku 14 wokwamkelwa kwakhe. Isiphumo liphezulu ichiza babonakaliswa emva malunga 120 kweentsuku zonyango.

Iimpawu "buspirone"

Iingcali ukumisela amayeza xa uziva ingozi, ebonisa uloyiko kunye nokukhathazeka, akukho ndlela ucaphuka yakhuthaza ziyenzeka wobulali neurosis kunye ubuthongo ukuphazamiseka, apho kukho uphawu ngendlela. Le mveliso ngokufanelekileyo unyango ukuphazamiseka somatic, DYSTONIA kwezityalo nokudandatheka, ukuphelisa uxinezeleko, ukurhoxiswa utywala.

Izimo ekufumaneni "Buspirone" iziyobisi

"Buspirone" (analogue beziyobisi ngokunjalo) iye Izimo. Ichiza original esalelweyo ukuba kwiimeko ezinjalo:

• glaucoma (uhlobo ezivaliweyo);
• iinkqubo enzima yezifo ibakho esibindini kunye nezintso;
• sokuwa;
• ukuphazamiseka ngentliziyo, iingxaki neempahla igazi;
• izitshanguba ye phecana sokuphefumla;
• myasthenia gravis;
• Hypersensitivity ukuba amacandelo;
• ixesha ngokuzala, wancancisa esifubeni sakhe;
• yobudala engaphantsi kwe-18.

Ukuba kukho Akuvunyelwe ngokungqongqo ukuba amisele iipilisi ukuba i "Buspirone" nomonde yimbali ukugula okanye ukuxhuzula.

Phambi kokuqala unyango kufuneka khangela nobuzaza isigulane ukuba ichiza.

Ukusetyenziswa kwemali, idosi

Ngexesha unyango lithetha "buspirone" ukusetyenziswa kumacwecwe ngokungqinelana iingcebiso gqirha okunyangayo. Isikhokelo esemthethweni iqulathe ulwazi olufunekayo ithamo nganye ezahlukeneyo nomonde, okt. yesekethe unyango ngamnye K. imisela ukusebenza unyango eyenziwa. Umthamo ixhomekeke yempilo yesigulane. ngcebiso ngokubanzi zezi zilandelayo:

• Isigaba sokuqala - 3 lidle 5 mg ka iziyobisi;
• ukuqhubeka unyango - ukunyuka kancinane ithamo ngokuhambelana isithuba seentsuku 2-3 (xa kukho imfuneko esinjalo);
• administering idosi iphezulu yemihla ngemihla ye-50 mg (xa kungekho yifuna).

Tablets "Buspirone" imiyalelo iimvume ukusetyenziswa uthathe kuphela indlela yonke, abanako songanyibilikisswa elulwelo, cuba kunye ukuhlafuna. Iyeza onxilileyo imali njengomvumbi yamanzi, ezithatyathwa nangaliphi na ixesha lemini ngokuzimeleyo ekudleni. Ixesha izinga elicetyiswayo yi iinyanga 4. I 'buspirone "elide eli xesha baphathwe ayikhuthazwa.

Effects ezingalindelekanga "buspirone"

Xa unyango ngamachiza ezinye abasabela engathandekiyo le ntsholongwane ziyakwazi ukuba andibhaqwa. Umzekelo, ukozela, ukwanda kokungazinzi impilo jikelele, ubuthathaka, ukudinwa, bengenamdla. Ukuba loo mayeza anefuthe ezinjalo kufuna kususwa iziyobisi. Ukuba qhagamshelana nogqirha wakho kunye nokwazisa naye iinguqu ezingentle emzimbeni emva kokuthatha iipilisi "Buspirone". Imiyalelo ukusetyenziswa kwiimeko ezinjalo kucetyiswa ukunciphisa ithamo arhente. Ukuba iziphumo ebezingalindelekanga ndingemkanga, ugqirha kufuneka endaweni namanye amachiza amayeza afanelekileyo ngakumbi.

Kwiimeko ezinqabe kakhulu, ukusetyenziswa "buspirone" kukhokelela yokuphazamiseka kwinkqubo yokwetyisa. Umzekelo, kusenokubakho isicaphucaphu kunye heartburn, kulandele ukugabha. intlungu kunokwenzeka kummandla epigastric. Kusenokubakho ezinye iziphumo ebezingalindelekanga. Zonke ezi mpawu zibonisa wayengabunyamezeli macandelo zeziyobisi.

Libanda, "Buspirone" iziyobisi

Ukuba isixhobo lisetyenziswa ngeedosi eziphezulu ngaphezu Kucetyiswa, loo mntu nazo iimpawu i libanda. Ezi ziquka isicaphucaphu nokugabha, ukuphazamiseka emathunjini lolunye uhlobo. Le Uyagula nomonde, ukuvala abafundi, inokuba ilahleko emfutshane sezingqondweni. Izigulane shiya ngokutsha emva unyango lithetha "Buspirone Sandoz", waphawula ukuba kungenzeka lesiphithiphithi, nemilenze lafa. Phakathi kwezinye izenzo libanda - nochuku, ukuba nochuku, utshintsho kaninzi isimo. Overdosing iphathwa yi lavage esiswini, ulawulo carbon yasebenza emzimbeni, unyango kwangumqondiso nokuqhuba ulawulo rhoqo of wegazi, izinga intliziyo, umsebenzi sokuphefumla. iyeza ngqo Umfanekiso iimpawu libanda, "buspirone" ayisekho. Dialysis kwiimeko ezinjalo engazisi yifuna.

Ukusebenzisana zizinto ezahlukeneyo kunye namanye amachiza

Maxa wambi xa indibanisela engavumelekanga iziyobisi ezithile iipilisi "Buspirone" imiyalelo ngokusebenzisa analogue icebisa ukuba ucinga abe lilalela kwisibonelelo yokuqala. Yinto eyaziwayo ukuba ichiza kufuneka ithathwe ngaxeshanye okudambisa, nadlamkisayo ngenxa ukuphucula isiphumo kwamachiza ezithathiweyo. Xa unyango "buspirone" yimfuneko ukuba akhutshwe ukusetyenziswa iziselo ezinxilisayo. Awukwazi ukudibanisa amayeza kunye Mao inhibitors ngenxa umngcipheko lobunzima unesifo.

Xa usebenzisa zombini "Haloperidol" ne "buspirone" egazini kunyusa izinga kweli chiza. Ukudibanisa amayeza with "trazodone" kukhokelela ekwandeni kakhulu ALT.

Ngenxa yoko-experimenti ezininzi ezibandakanya izilwanyana, ifuthe elibi eziphilayo zange ibhaqwe ngexesha unyango. Nakuba kunjalo, ukwenzela ukuthintela ngayo engathandekiyo omzimba ukuyamkela ngayo ukubanceda.

"Buspirone" imiyalelo ukusetyenziswa yi njengesixhobo ogama yokucolwa esibindini. Kule nkqubo inxaxheba CYP3A4, ukuba isoenzyme igalelo ukulungiselela processing ephilayo. Ngenxa yesi sizathu, i-intsebenziswano zingenzeka "buspirone" kunye neziyobisi ezi inducers, okanye inhibitors ze enzyme.

Iimpawu lokusebenzisa ichiza

Ukuba, ngethuba zisanyisa, kukho imfuneko unyango, ngokusekelwe ulwamkelo "buspirone" uncancisa bayeka okwethutyana.

Kukho ezinye izithintelo xa ukuphazamiseka ukusebenza nezibilini. Umzekelo, ukuba ngaba unengxaki yesibindi kufuneka silumke ngexesha unyango kunye basoko belwakhele umkhanya iinguqu ezenzeka ngayo impilo. Izimo kuphela ukungaqheleki kakhulu ekusebenzeni umzimba. Kukwasebenza kwanjalo kuyo umsebenzi nezintso.

Ngokuphathelele ukuqeshwa arhente kbavelisi ezahlukeneyo, xa Vol. H. "Buspirone Sandoz" iziyobisi, uhlolo lwezonyango lubonisa imfuneko bahloniphe imithetho ethile. Ukubhala ngaphandle amayeza, ingcaphephe kufuneka uqaphele ukuba esi sixhobo akanako ukuphelisa uyeka evela benzodiazepine, nenjongo yayo kwiimeko ezinjalo akwenzeki, ukuba ube sowuyisusile na isiyobisi anxiolytic yaveliswa phambi kokuba unyango.

Izigulane kufuneka bazi ukuba iipilisi "Buspirone" enokuchaphazela ngononophelo, ingakumbi ekuqaleni unyango, ngoko ke kungcono ukuba ayeke okwethutyana kwimisebenzi ebandakanya uxanduva ekhethekileyo kunye ingqalelo ukwanda. Eminye imisebenzi kunokuba yingozi empilweni.

Ngokumalunga therapy "Buspirone" kuthetha, oogqirha yokwenene malunga ichiza kakhulu omhle. Noko ke, iingcali zibonisa ukuba kuyimfuneko ukwabela kakuhle kuphela ezibonisa ezifanelekileyo kunye ngeedosi ezingcono. Kufuneka kuqatshelwe ukuba uxinezeleko namaxhala ukusuka impembelelo esisigxina elibi ntshikilelo ngemihla, unyango kunye anxiolytics ezivela Kudla ngokungabikho mfuneko.

Kukwamkela kuthetha izigulane "buspirone" kunye umthamo ezahlukeneyo, umz iziyobisi "buspirone 10 mg 'ukureyithwa zimele ukusetyenziswa indlela ephumelelayo. Abantu ziphathwa olu nyango, qaphela ukuba ugqirha abaprofeti bakho ababengqina kubo, ukuba babe ukusetyenziswa ngononophelo amayeza ezithile, ezifana zokucwangcisa yomlomo, amayeza ngenxa seswekile, nezenzi kuthagetha ekunciphiseni uxinzelelo oluphezulu lwegazi, iziyobisi ukuphelisa uxinezeleko kunye iziyobisi ezifana glycosides inhliziyo , neuroleptics.

ukusilela kwezintso kunye kakhulu zesibindi ukuqina ifuna ukuncitshiswa kweeyunithi balawule. Kule meko, indlela "Buspirone Sandoz" ngokutsha indlela abantu ukuchaza unyango kufuneka ukuba kulawulwa phantsi kweliso gqirha. Kucelwa nithathele ingqalelo le utshintsho incinane impilo.

Izigulane ngamayeza sokuwa zange emiselweyo kuba umngcipheko ukuxhuzula. amakhambi anjalo kwezi zigulane kuyingozi kwaye kufuneka wenziwe ukusetyenziswa kwezinye amayeza. Abaguli ngokusetyenziswa kakubi iziyobisi yaye imbali ukuxhomekeka ichiza kufuneka ziphathwe phantsi kweliso elibukhali of a ingcali (elivela ngokuxhomekeke "buspirone" wayengekho).

Uphononongo lubonise ukuba "Buspirone" emva kweeveki 3-4 zonyango xa alamu nako, ngoko akukho ndlela awanyange ixesha elide. Ngenxa yokungabikho kwengcaciso malunga nokhuseleko kweziyobisi oonyana ukuqeshwa wakhe wenza ukuba abantu abangaphantsi kweminyaka eli-18 ubudala.

Unyango lwe Ukrainian lunee ntlobo ezahlukeneyo kweziyobisi kunye neziyobisi i "Buspirone hexane" buyekezwa ezinye iingcali zibonisa njani unyango angasebenzi ngenxa yokuba ukulala iingxaki, ukuvela ucaphuka kunye nexhala ngezinye uphawu ukuphazamiseka lengqondo kakhulu.

Analogs, ukubuyekeza ichiza "Buspirone"

Ezitshintshwayo analog ichiza kufuneka wenziwe emva kokufumana iingcebiso kagqirha. Kukho indawo elungileyo ukuze amayeza, "Buspirone" - "Spitomin". Baqinisekiswa kubonisa ukuba isenzo yayo liyafana isenzo-mali yokuqala. "Spitomin" isetyenziselwa unyango yezo meko ofihla yaye "Buspirone". Ukuphonononga izinto ezilungileyo, ngoko ukuba ufuna kunokwenzeka ukuba basebenzise eli obambeleyo, kodwa ke kuphela emva kokubonisana yincutshe. A nomphumela ofanayo ifunyanwa ngenxa yobukho eyona nto efanayo esebenzayo. I 'Spitomin "kakhulu ngempumelelo kubonisa unyango izigulane kunye ukuphazamiseka ixhala.

Emva konyango nge "Buspirone" angqina bangazishiya ezahlukeneyo, kodwa ziyindlela ngenxa yonyango loo positive. Ngaba kuqinisekiswa impumelelo yayo? Izimvo kumagqirha zibonisa ukuba imveliso kunye isithako buspirone hydrochloride asebenzayo alwa ngempumelelo nxamnye ekubonakalisweni ixhala bayashiyana ubungozi imvelaphi, kodwa isiphumo sayo kanye phantse engaqapheleki, nto ingabonwa kuphela emva kwexesha elithile, oko kukuthi - emva kweveki enye okanye ezimbini. Ukuze ubone kangangoko kunokwenzeka unyango, kufuneka siphathwe inyanga enye.

"Buspirone" ifumana iimpendulo ezakhayo izigulane kwiimeko apho bekungekho iziphumo ebezingalindelekanga, kunye neziyobisi yakhe nempilo entle. Amaxesha apho kuya kubakho iziphumo esibi ephilayo, kodwa kunqabile kakhulu xa umzimba angagqali amacandelo beziyobisi. Ukususela ncomo, oko kwazeka ukuba unyango ukuze zikhatshwe Unyango kunye nemisebenzi sotsioterapevticheskimi. Ngamanye amaxesha izigulane kufuneka basabele ezibi zesisu, isiyezi kunye buthathaka. Libanda - a amila.

Ngenxa yoko, ukusetyenziswa kweziyobisi "Buspirone" iimpendulo yezigulane ngayo Kakade ke, kunqabile ukuba ushiye ulwazi malunga nemiphumela emibi kakhulu. Le khosi kufuneka zisekelwe iimpawu ngamnye umzimba womntu, impilo yakhe, nezona ngalinye amathamo kunjalo. Ngaphandle kolawulo rhoqo kugqirha, isigulane kufuneka ufunde imiyalelo ngaphambi kokuqalisa unyango.

"Buspirone" - ichiza oko abadli kukhokelela kuphuhliso yeziphumo ebezingalindelekanga kunye libanda, non-eziyobisi, emibi emva wokucinywa kwayo, kwaye kwiimeko ezininzi wenza umsebenzi wayo.