Bacteriophages: Iintlobo kunye nenjongo

Phage lysis - inkqubo ukutshatyalaliswa iintsholongwane ngu phages, ngokuqhelekileyo kwenzeka organ abachaphazelekayo ngexesha recovery kulogo. Ukuba self-impiliso ekungazange kubekho injengayo, umzimba banokuncedwa ngokubonisa bacteriophage engqinelanayo, nto leyo enkampanini eyenza. bacteriophages ebizwa amagciwane iintsholongwane engena kwaye ibangele nokuchithwa kwazo (lysis) kwintlanganiso kunye naye basengozini iiseli abe nenkani.

Xa bacteriophage lesiGrike lithetha "edla iintsholongwane." Kwindalo, ezi eziphilayo zahlukahlukene kakhulu kwaye ke sikhulu kwaziwe amaqela wentsholongwane egazini. Phages ezi iintsholongwane ezahlukeneyo izityalo, izilwanyana kunye nesakhiwo yabantu lunzima kakhulu. Bona afumaneka imvula, umoya, umhlaba, ukutya, ngokumalunga nezifundo eluswini, uboya isilwanyana, ngamafutshane, naphi na apho kukho iintsholongwane.

Kwiminyaka yakutshanje, benomdla kwi bacteriophages zisetyenziswa eyenye antibiotics. Oku akumangalisi, kunye nabo kunye namanye amachiza kuchaphazela ngqo kwamagciwane. Noko ke, le mithi aziwa iyingozi nje kuphela nezihluma yayintsholongwane eyosulela, kodwa ngenxa eluncedo. Bacteriophages, iintlobo ezahlukileyo, enze ngokukhetha, kuba kuphela bacterium "abo", eshiya kwitekisi kwayo. Eneneni, ukuze izazinzulu yaye akazange ceba amagama, kulula kakhulu ukuba baye kubabiza ngokulandelelana iintsholongwane leyo apho edangatyeni.

Bacteriophages: Iindidi

Velisani streptococcal, coliform Proteaceae, klebsiellezny, Staphylococcus, Pseudomonas, Salmonella, segazi, bacteriophage icesina kunye "Intestifag" yaye "Piobakteriofag".

amalungiselelo Active ixhomekeke amaqondo ukuxutywa apho lysis inkcubeko ezibuthathaka. Ngenxa yoko, titer we-10 kule ngokuzalana kuthetha ukuba imiboniso lytic iipropati bacteriophage esebenzayo kwindawo ukuxutywa kwe-1 000 000 amaxesha. Xa amaqondo obushushu 4-6 iziyobisi C baya kugcina iimpawu zazo ukuya kwiminyaka eli-12.

Kuxhomekeka iifomu ukukhululwa bahluka bacteriophages msebenzi. Iintlobo machiza kuchaphazela zombini Iintsholongwane ngamnye, yaye ezininzi ngexesha elinye. Monophages kuchaphazela Ngeentlobo ezininzi iintsholongwane efanayo. K amalungiselelo complex (polyvalent) ziquka bacteriophage "Sekstafag" onako ngaxeshanye zinqanda umsebenzi staphylococci, streptococci, kuquka enterococci, Pseudomonas ne-Escherichia coli, Proteus, Klebsiella. Ngaphezu koko, kukho "Intestifag" yenzelwe kunyango lwezifo isisu, iquka indlela iSalmonella, icesina, segazi, proteus, coli kunye streptococcal (abathintela enterococci) phages.

Amachiza asetyenziswa dysbacteriosis, usulelo isisu, inflammations kwenkqubo enzala kunye broncho-pulmonary izixhobo ekunyangeni iinkqubo yokubolisa, ngokunjalo nezifo kwisisu ngomlomo kunye sinuses. Zisebenziselwa ngaphakathi, kuquka ngokohlobo enemas, kwaye ekuhlaleni - ukususa, ahlambe amanxeba, douching. Umzekelo, "The Bacteriophage Klebsiella polyvalent nyulu" kuba ozeny unyango, rinoskleromy, izifo ezibangelwa igciwane Klebsiella pneumonia, esetyenziswa yi inhalation kwi izitshanguba uqhoqhoqho, kwingqula kunye pharynx, turunda elawulwa nkxu emanzini, otitis, ezisetyenziswa ngeentlambululo in sinusitis. Xa Ngokuzimela, enterocolitis, urethritis, inyumoniya ichiza athathwa ngomlomo.

Bacteriophages babe ubunzima yeenzuzo phezu antibiotics. Abanawo ziziphumo ebezingalindelekanga, abelwe nokuba iintsana kunye nabasetyhini abakhulelweyo, bona ayikhobokisi. Baya zinokudityaniswa kunye naziphi na iziyobisi, kwakunye nokusetyenziswa kuthintelo kwezifo ezosulelayo. Ezi amalungiselelo nefuthe kuyingenelo kuphuhliso sifo, musa abayithintelayo iintyatyambo zendalo kunye nefuthe lazo kuyabonakala ngaphakathi kweeyure 2-4 emva kokungenisa. Abayi ukumelana kwamagciwane.

Enye ethile are bacteriophages. Iintlobo namhlanje kusetyenziswa amayeza, kodwa bambalwa, nto leyo enciphisa ukusetyenziswa kwabo izifo ezininzi.

isicelo Outlook

Ukuze isicelo ngempumelelo iimveliso zebhayoloji, ukuba kuyimfuneko ukumisela uvakalelo iintsholongwane kubo. Noko ke, izazinzulu uye waphawula indlela yenkqubo enomdla: uvakalelo ezincinane phages akufuneki lifinyele, kodwa kwandisa, ngenxa ukutyebiseka imveliso kunye neenkcubeko ezintsha. Ukuza kuthi ga ngoku, le staphylococcal bacteriophage lyse ngempumelelo-90% yazo zonke iintlobo zonke iintsholongwane wakhululwa ngexesha izilonda nokulimala.

Iingcali ezininzi izifo ezosulelayo bakholelwa ukuba kungekudala unyango phage kuza kuyitshintsha ekulweni izifo. Immunologists ukubona nethemba ukusetyenziswa kwezi mali apho Immunopreparat namandla. Ngokutsho kwizifundo yohlalutyo kwiminyaka embalwa elandelayo, enye yeendawo nathembisayo Pharmacology iya kuba imveliso phages.