Treponema pallidum (Treponema pallidum) - i-arhente causative of negcushuwa

Treponema pallidum - yibhaktheriya eyingozi kakhulu, i-arhente causative of negcushuwa. Utyhutyha ngokukhawuleza emzimbeni womntu ngezinga elifanayo ngayo Ukhuthaza, ngaloo ndlela zichaphazela kakhulu izibilini.

inkcazelo iintsholongwane

Treponema pallidum - iintsholongwane ukuba inwebu yeseli. Uyakwazi ukuba aphile ixesha elithile kokusingqongileyo. Le bacterium fanele ku spirochaetes. Kubonakala ngathi curls ezincinane ephotheneyo, nto leyo inokuthabatha ithuba iziqwenga ezisibhozo ukuya kwezilishumi elinesibini. Nje inani labo kunye nohlobo igciwane ibanjiwe xa kwenziwa i microscopy smear.

Esi silwanyana ukuba ngenkankulu ezinemibala idayi, asetyenziswa eziphilayo. Ukuze ubone igciwane kusetyenziswa umehluko microscopy. Oku kubangelwa yinto yokuba iqokobhe ibhityile kakhulu micro-eziphilayo phantsi kwempembelelo zotywala kwaye ngokukhawuleza umonakalo (kwaye oko nje awusetyenziswa kumbala nitrogen). Xa isilivere ngumfanekiswana intsholongwane iba umbala omdaka-omnyama.

Koda kube nini amagciwane live

Treponema pallidum uxhumane izinto (ubukhulu becala zokulala kunye iitawuli) iya kuhlala injalo de kube zeendawana owomileyo, apho ke. Kwiimeko ezininzi amathe kukhululwa ulwelo nezilonda kunye erosions, amadlozi, njalo njalo. D. Xa amaqondo obushushu mahlanu anesihlanu izidanga igciwane ingaphila malunga neshumi elinesihlanu lemizuzu. Xa die ngaphezulu ngokukhawuleza. Ngeli abilayo intsholongwane kufa kumcimbi lemizuzwana, oko kukuthi, phantse ngephanyazo.

Yeyiphi kuphazamisa iintsholongwane

Kuba Treponema pallidum bume ezithile eziyingozi kunye nezinto:

• bismuth and esiyityhefu;
• mercury;
• penicillin;
• kwealkali acid;
• ebulala magciwane;
• neviniga notywala;
• UFO kunye nokukhanya.

Ngokutsho izifundo kunye imifuniselo lwenziwa zizazinzulu, kwafunyaniswa ukuba eli gciwane maxa wambi qhubeka ngexesha elithile kunye neemeko ezibi yona. Umzekelo, kwi imeko embi, phantsi ekukhanyeni, urhulumente eyomisiweyo okanye kukho ioksijini. Ukuba uhlangabezana ikopi silwanyana, oko onokuphila bume engentle kuye iminyaka emithathu.

ukukhula Treponema kunye nezakhi ezinkulu

Treponema pallidum kakubi ulinywa ngenxa capriciousness yayo. Iiseli ngeembumba intshontsho kunye yabantu azamkelekanga ezifanelekileyo ukulinywa le ephilayo. Kukho iindlela ezimbini, zibe nokwaziwa ngayo inkcubeko. Lokuqala - iibhaktheriya ziphatha imivundla elebhu, ulindele ukuba uphuhliso kwezi zilwanyana orchitis ethile. Okwesibini - treponemu zikhuliswa kwi akhethekileyo kumajelo eendaba phantsi ioli bezimbiwa. Ubukho kwezi zinto ziphilayo kuyimfuneko ukufumana awakwazi ngayo negcushuwa uzimisele.

Phathogenicity Treponema pallidum

Izifo iintsholongwane treponema pallidum uneempawu zawo:

• Bulelani kwiproteni adhesin ukuba zisebenzisana fibronectin mucosal ezinikiweyo "enamathele" nokuthwala iiseli;
• ubukho myofibrils nemilo Ukonakala Treponema pallidum ukukhuthaza ukungena nzulu kwaye abangele yokufuduka umzimba;
• antifagotsitarnaya umsebenzi kungenxa ekukwazini iintsholongwane ukubophelela fibronectin;
• uba asha ngenxa yobukho inwebu lipoprotein;
• treponema pallidum ukumelana kwiiarhente antibacterial ngenxa Ukwahluka lepropati antigenic kunye nokubanako ukuyilwa L-iifomu, nto leyo eyenza kube nzima ukwenza isitofu sokugonya;
• Ezi bacterium nje nako ubomi interstices, kodwa ukuze nande khona.

Omzimba Treponema pallidum

Treponema pallidum kakhulu abayiqokeleleyo inwebu yangaphakathi. Ngoko lula ezosulela kuphela ingokwabelana ngesondo, kodwa kubomi bemihla ngemihla. Kaninzi ngenxa iitawuli, impahla okanye ukwanga. Ngelishwa, umzimba womntu abakwazi ukumelana nezifo kwezi ntsholongwane. Ngoko ke, kwanasemva unyango epheleleyo wesifo negcushuwa unako ukubuya.

Ukuze ubone isifo igazi kuthathwa negcushuwa. Uninzi igciwane baye omzimba ukuba Treponema pallidum. Xa isifo zamabanga nezolo - ngo-88 no-78%, ngokulandelelana. Abanye ke mhlawumbi hayi ubonwe okanye azikho kwaukubakho. Kodwa ke ukungabikho omzimba Ayibonisi ukuba unyango iyaphumelela. Kwinqanaba abagxothwa le lomzimba sifo efumaneka ngokubanzi kuphela-20 ekhulwini lezigulane.

Emva kweeveki 1-2 ukususela ekuqaleni sifo uhlalutyo serum lo. IgM kunye IgA antibodies treponema pallidum kwi serum kuvela ngeli thuba. Ngeli xesha ukusuka kwiinyanga ezintandathu ukuya kwiinyanga titers ezilithoba immunoglobulin ukufukuka, ngoko iqala ukuhla kwenani labo. Ngokusebenzisa ixesha owayo ngezantsi ixabiso elimisiweyo neqondo omzimba. Ezinye ayinakusasazeka ukusuka kumama ukuya emntwaneni.

IgG izilwa kuvela kwiiveki 3-4 emva kokuba usulelo kunye negcushuwa. Iveki 6-9 ukufikelela incopho yayo. A ndzo elikhulu lomzimba alondolozwa ukuze ixesha elide, kwaye kunciphisa ngokucothayo kakhulu yaye kuphela emva konyango. A titers lentsalela usenokungaguquki emzimbeni ubomi.

izilwa Treponemal ingaveliselwa kuphela Treponema pallidum. Ngoko ke, xa ubukho banokufaka amabango ngokuchanekileyo ukuba negcushuwa ngalo mzuzu okanye isiwe ngaphambili.

Iimpawu zokugula of Treponema pallidum

Kukho inani kweempawu ezibonisa phambi emzimbeni womntu Treponema pallidum. Xa kubonakala kuyimfuneko ukuba unikele ngegazi ukuze negcushuwa. Iimpawu zisenokwahluka ngokuxhomekeke ibakala sifo.

Kule lokuqala:

• izilonda ezibuhlungu kunye chancre, ibekwe emlonyeni, ezinqeni okanye esini;
• iindawo nkovu kalanga;
• ngokuzimeleyo nezilonda ke inzala kwimali ubuncinane kwiiveki ezintathu, inkqubo elinokuthatha ukuya kuma kwiinyanga ezintandathu.

Ngosuku lwesibini:

• macala irhashalala sakuba syphilitic ivela emzimbeni;
• intloko ebuhlungu, umkhuhlane, umkhuhlane;
• iindawo nkovu kalanga;
• maxa wambi alahlekelwe iinwele zakhe, iintsumpa angasese kuvela ngokubanzi.

Kulo wesithathu kukho ukoyiswa:

• luvo;
• ingqondo kunye umnqonqo;
• izibilini zangaphakathi;
• amathambo.

Kumanqanaba wokuqala nowesibini unyango ngempumelelo esibanzi equka le mithi, ukuyifundisa siqinisele kunye immunostimulants amalungiselelo. Kodwa ke ukuba ixesha akafane abone ugqirha, iminyaka ke embalwa kamva waqalisa kwinqanaba lesithathu sifo, ukunyanga ukuba phantse akunakwenzeka.

Njengoko kutyhilwa treponema baluthuthu?

Ukuze ubone enoba kukho nayiphi na umzimba neentsholongwane ezibangela negcushuwa, yinto uhlalutyo efanelekileyo. iinzame Treponema pallidum zezonyango namhlanje kungabonwa ngeendlela ezininzi:

• Inxaxheba kwinqanaba lokuqala negcushuwa isigulana iyosulela kakhulu kwaye uqaqambisa ehlabathini ezininzi iintsholongwane. Kulo mzekelo i-smear microscopy. Ukuze ufumane iziphumo ezichanekileyo, izilonda waphatha washout-saline ukuba kokuphazamisa izihluma. Emva koko wenza kokuphalwa, waza wenza smear.
• iimvavanyo Non-treponemal. Kukho kusetyenziswa iindlela zokuhlola. Ukuba ulungile moshilongo lokuqala ulandele-up ngexesha unyango kunye noviwo clinical. Kodwa ezi mvavanyo badla ukunika iziphumo okungamanga. akufunekanga bekho emzimbeni Treponema pallidum kule meko. Kungenxa lwegazi (elilwa ezisegazini) engasetyenziswa gciwane.
• iimvavanyo Treponemal asetyenziswa ngayo ukubona Treponema pallidum. Ezi ndlela zisetyenziswa ukuqinisekisa uxilongo kunye nokukhutshwa negcushuwa ngexesha lokuhlolwa engalunganga.