"Simvastatin": ncomo, kubonakala ukuba ukusetyenziswa, ixabiso kunye analogue

Kutheni kufuneka iyeza "Simvastatin"? Baqinisekiswa malunga ichiza kuya kwenziwa phambili umganyana. Siya kunixelela ukuba ngalo eli chiza ifumaneka ngendlela apho anako kuyabonisa, iziphumo ebezingalindelekanga kunye Izimo isasetyenziswa, wobeka phi kubiza, kufuneka isetyenziswe kakuhle ngayo, njalo njalo. D.

Packaging, ifomu Product kunye nokwakheka

Drug "Simvastatin" uya ezithengiswayo ngohlobo amacwecwe. Zinelungelo biconvex imilo ngeenxa ngamanqaku kwelinye icala, kwakunye emhlophe. tablets camera, macwecwe eziqulathe 10 mg simvastatin. Kwakhona medicament iquka amacandelo abangabancedani butylhydroxyanisole, lactose, nemagnesium stearate, starch prozhelatinizirovannogo, talc, kunye microcrystalline kwincindi.

Xa iphakheji, unako ukuthenga amayeza "Simvastatin"? Iimpawu zibonisa ukuba ukusetyenziswa kwemali echazwe kwi imiyalelo, nto leyo uqulathwe ipakethi kwikhadibhodi. Kukho kwakhona zibekwe kunye namadyungudyungu amabini kunye iipilisi (iziqwenga ezili-10).

imiphumela kwemithi

Njani ichiza "Simvastatin"? iingcali Guest ibonisa ukuba amachiza lipid-lisibekele. Oku kwenziwa ofana nawo.

arhente ebheka yinto lactone engasebenziyo. Xa abantu, oko hydrolyzed, yaye kamva yenza yemvelaphi hydroxy-asidi.

Ukusetyenziswa ichiza akubangeli beqokelela ityhefu. It umzimba ngokukhawuleza kwaye wabandakanyeka kwiinkqubo ezininzi synthesizing.

Iimpawu ichiza

Yintoni iimpawu iyeza "Simvastatin"? Ukuphonononga uxele ukuba esi sixhobo inceda ukwehlisa amanqanaba plasma of triglycerides, cholesterol iyonke kunye ezisezantsi-mninzi lipoprotein.

Isiphumo therapeutic emva kokuba uqalise ezithatha ichiza kwenzeka kwisithuba seeveki ezimbini. Isenzo ichiza ihlala izinze ngexesha unyango. Emva kokuba kurhoxiswe amacwecwe cholesterol ngcembe ubuyela ekwenzeni sokuqala.

Pharmacokinetics

iziyobisi "Simvastatin" sebenzi elingakanani? Iingcali Guest bathi kukufakwa kwemali liphezulu kakhulu. Emva kokufumana amayeza ibe ingqalelo yayo ephezulu egazini kuphunyelelwa emva kweeyure 1.5-3 kwaye kwehle nge-90% emva 12 kweeyure. Unxibelelwano kunye plasma nama-95%.

Nethe beziyobisi esibindini. Half-ubomi metabolites yi malunga neeyure ezimbini.

medicament ziboniswe endleni kwakunye kwanga nezintso.

Drug "Simvastatin": zikhombisa ukuba ukusetyenziswa

Kwezi mali ekucetyiswa ukuba zisetyenziswe hypercholesterolemia, kunye nesifo sentliziyo. Ukumisela amayeza kufuneka ibe kuphela ngugqirha emva kokuba axilongwe.

Ngoko na kunjalo uyakwazi ukuthatha iipilisi 'Simvastatin "? Ukususela oko kuthetha ntoni na eyabelwe? Ngokutsho imiyalelo, ichiza Kucetyiswa xa:

• hypercholesterolemia yokuqala;
• lo kwawo yokudla yokudla eliphantsi cholesterol kunye nezinye ungenelelo non-drug (ukwehla kobunzima, umsebenzi emzimbeni) kwizigulane kunye yamafutha semithambo;
• hypertriglyceridemia ezidibeneyo hypercholesterolemia, nto leyo walungisa imithwalo ngokwasemzimbeni ukutya okhethekileyo.

Ziziphi ezinye iimeko emiselweyo amayeza "Simvastatin"? Ubungqina obubonakalayo buxela ukuba basisebenzise esi sixhobo cinga ngoku:

• uthintelo engabalulekanga iposi;
• ekunciphiseni umngcipheko ukuphazamiseka zentliziyo (umzekelo, kobuchopho okanye stroke);
• ukukhubazeka ngenxa yamafutha kwiinqanawa ivaleke.

Izimo

Ngoku uyazi ukuba iyeza kumiselwe "Simvastatin". Ubungqina obubonakalayo buxela ukuba kusetyenziswe isixhobo ziye uchazwe apha ngasentla. Nangona kunjalo, eli chiza kukho Izimo. Le meko zilandelayo kusebenza kubo:

• isifo sezihlunu (okanye ekuthiwa-myopathy);
• isifo sesibindi esivulekayo kwisigaba esebenzayo;
• kweminyaka eli-18;
• Ukuphakamisa ucingisise enqanda zesibindi (kubandakanywa umyalezo ayaziwa);
• hypersensitivity ukuba ichiza okanye amacandelo yayo ngamnye (kubandakanywa ukunyamezelana lactose);
• hypersensitivity kwezinye iindlela statin series.

reception ngocoselelo namalungiselelo

Medicament "Simvastatin", ixabiso oboniswe apha ngezantsi, kunye ngokukhethekileyo enikwe abaguli kakubi utywala, kwakunye nabantu abalandelayo abohlukeneyo (kunye nonyango immunosuppressive).

Ngaphezu koko, lo mbandela kuthetha ngenkathalo esithathwe kwiimeko ekhokelela kuphuhliso ukusilela kwezintso (umz, hypotension, izifo ezihlasela zosulele yendalo ezasulelayo, zancitshiswa, okanye ngokuchasene noko, ukuba ufe ukwanda esiqwini izihlunu, wavakalisa yokucolwa ezidalwe ukuphazamiseka, sokuwa, ukuphazamiseka electrolyte balance, utyando, kuquka zamazinyo kunye trauma).

Drug "Simvastatin": nokusebenzisa balawule

Ingqalelo phambi kokuba kuqalwe unyango uthetha isigulane kufuneka bangenele umgangatho ukudla hypolipidemic. Phela, kufuneka ilandelwe kulo ekuhambeni unyango.

"Simvastatin" icwecwe ezilawulwa kanye yonke imihla ngokuhlwa. Nangona ukuthatha le iyeza kufuneka idibana kunye nasekusebenziseni ukutya.

Esithathwa ekucetyiswa ukuba unyango ngamachiza le hypercholesterolemia yi 10-80 mg ngosuku.

utshintsho ithamo kufuneka wenziwe kumathuba ngenyanga. Okokuqala, isigulane kufuneka athathe 10 mg, ngoko-20, 30 njalo njalo. D. Kwiimeko ezininzi umphumo eliphezulu zonyango lufumaneka xa efumana 20 mg beziyobisi.

Le umthamo ichiza kuxhomekeke kubudala yesigulane, imeko yayo njalo njalo. Kulo mba, iyeza kufuneka amisele ugqirha, emva kokuhlola umguli kunye novavanyo lonyango.

ukusabela ezingalunganga

Njengaso nasiphi na isiyobisi, medicament "simvastatin" Kwakhona iziphumo ebezingalindelekanga. Phakathi ixhaphakileyo zezi zilandelayo:

• Besisu iintlungu, hepatitis, ukuqhina, pancreatitis, flatulence, ukugabha, enzayim zesibindi eziphakamileyo, urhudo, nentliziyo.
• syndrome Asthenic, ingqiqo kakuhle na incasa, intloko ebuhlungu, ukungaboni, isiyezi, peripheral neuropathy, sokulibala, paresthesia, amahlaba kwezihlunu.
• Angioedema, eosinophilia, polymyalgia rheumatica, urticaria, lupus-ezifana syndrome, vasculitis, dyspnea, thrombocytopenia, komzimba, ukunyuka kweqondo neentlenge erythrocyte, ukuthoba eluswini, ifiva, photosensitivity, samathambo.
• Irhashalala, alopecia, dermatomyositis, ukurhawuzelela.
• amahlaba Myopathy, rhabdomyolysis, myalgia, ubuthathaka, izihlunu.
• Anaemia, kunciphise amandla, intliziyo, ukusilela kwezintso (yondele).

imiyalelo Special ngokufumana medicament

Ngaphambi usebenzisa imveliso kufuneka ufunde ngenyameko imiyalelo. Ithi:

• phambi kokuqala unyango kuyimfuneko ukuqhuba isifundo kwesibindi;
• "Simvastatin" ichiza kufuneka kuthathwe xa ukusilela kwezintso kunye nengozi yokuba rhabdomyolysis;
• iyeza kunokuba neziphumo ezibi kwimveku;
• ayikhuthazwa ukuthatha iipilisi ukuba abafazi nabantwana ubudala musa ukusebenzisa zokucwangcisa;
• ngexesha unyango kufuneka ukuba bangaxhatshazwa utywala;
• ngexesha therapy, isigulane kufuneka athobele yokudla hypolipidemic;
• ukwamkelwa ngaxeshanye juice grapefruit ngoyo iqondo ubukhali reactions icala;
• ukulungiselela ukuba abe monotherapy, yaye kunye nokusetyenziswa sequestrants inyongo acid.

Analogs neendleko ichiza

Ngoku uyazi ukuba sisiyobisi "Simvastatin". Analogue, ixabiso eli yeza kuya kunikwa ngoku.

Ukuba isicelo akunakwenzeka oku kungakwenza kufakwe kunye namanye amachiza afana "Simvakard", "Avestatin", "Holvasim", "Aktalipid", "Sinkard", "Aterostat", "Simplakor", "Vasilip", "Simli" "Vero -Simvastatin "," Simgal "," Zovatin "," Simvor "," Zocor "," Simvastol "," Zorstat "," Simvalimit "," Ovenkor "," Simvakol "," Simvageksal "kunye t. d.

iziyobisi Price "Simvastatin" ayikho eliphezulu kakhulu kwaye engange malunga 240 tablet-20.

Izimvo medicament

izigulane ezininzi ziye ukhe "Simvastatin" tablets, phawula ukusebenza kwayo phezulu. Ichiza lihlisa ngokukhawuleza cholesterol, nokuthintela uphuhliso zizifo ezahlukahlukeneyo.

Noko ke, ezinye izigulane awonwabanga abadlulayo emva uphinde uvuke cholesterol unyango kwaye usoloko kuziwa lokwandlalela.