"Excedrin": noogxa. Eyanceda migraine "Excedrin": ncomo, amaxabiso, analogs

Migraine - lo sifo, ongayi kuba nako ukudluliselwa ngaphandle analgesics. Uhlaselo uyakwazi kuthatha iintsuku-4. Le ndoda kweli xesha ithe amandla ayo ukusebenza. Ngelo xesha usebenzisa amayeza ngamandla ukuphelisa intlungu throbbing. Kodwa ke, ngelishwa, uninzi izixhobo ukuphelisa ukuqaleka ezinjalo, iziyobisi kwaye kungakhokelela ekubeni esi sifo kuba ezingapheliyo. Pharmacology Modern liqulunqe ichiza enkulu elitsha. Iindlela, kuhle balahle migraine, ukunciphisa isakhono ukusebenza, kodwa ayikhobokisi, ichiza "Excedrin". Analogs beziyobisi ayikho ngaphantsi kakuhle.

inkcazelo emfutshane

Eyanceda migraine "Excedrin" i amalungiselelo ngoweqela of analgesics-antipyretics zidityanisiwe. Isetyenziswa enentloko engapheliyo. Kukubek 'lithetha "Excedrin" evela uqaqanjelwa. Kulo mzekelo, iyakwazi nokuba ukuthintela uhlaselo.

Ukubunjwa ichiza

ukusebenza Eli chiza xa ilele izithako yayo. Iyeza iqulethe:

• acetylsalicylic acid;
• caffeine;
• paracetamol.

Kuyinto ngenxa kwezi zinto lineziphumo ezahlukeneyo emzimbeni. Ngenxa yoko, eqinisekiswe ukusebenza ngoko nangoko, iintlungu wama ngokupheleleyo.

I-paracetamol kwi isixa 250 mg, Acetylsalicylic acid - 250 mg, kunye caffeine - 65 mg enye cwecwe iziyobisi "Excedrin". Ukubunjwa ke apha kuthetha izithako ezisebenzayo zinkulu kakhulu. Ngako oko ke kucetyiswa ukuba usebenzise iziyobisi kunye balumke ngeyona ndlela. Kufuneka Izigulane uthathe ingqalelo idosi hayi kugqithisela.

Ukongeza, eli chiza ziquka izithako abangabancedani:

• giproloza;
• microcrystalline neselulosi;
• stearic acid.

Effects on emzimbeni

Amacwecwe migraine "Excedrin" ezenziwe ngezinto ezintathu ezahlukeneyo kulo iipropati ezahlukeneyo. ukuhlanganiswa ivumela ukuphelisa intlungu naluphi na uhlobo. Ekubeni ukuhlaselwa migraine kunye ubuhlungu ngokwaneleyo elide kakhulu, ukuba bahlukane ngaye kufuneka amayeza kakhulu kunene. Ukuba enjalo ichiza "Excedrin".

Yintoni le sixhobo iye kwakhona wavakalisa impembelelo yayo yaye yintoni umphumo? Impendulo yalo mbuzo siyifumana ifuthe emzimbeni kwicandelo ngalinye ziqulethwe ichiza:

1. Paracetamol. Le into uba iipropati anti-ezithintela ukosuleleka kunye antipyretic kunathi. Kubalulekile ukwazi nomthelela iziko ingqondo onoxanduva lokulawula iqondo lobushushu kule ngxenye. Indima ebalulekileyo ekupheliseni migraine iye umgangatho anti-ukudumba, kuba icesina asisiso iimpawu zesi sifo.
2. Acetylsalicylic acid. Component yohlukile iipropati ucaca antipyretic. Uyakwazi ukuba isantya kwaye ukuphelisa ukudumba. Xa oku kunciphisa intlungu. Acetylsalicylic acid kungavimbela kukuvela egazi. Ime inkqubo nokudaleka kwinqanaba zeselula, ngokugqibeleleyo uphucula igazi kwegazi kwiindawo ebushushwini babo.
3. Caffeine. Indima le into ukwenzela ukunciphisa intlungu kakhulu ebonakalayo. Aspirin kwakunye paracetamol ungakutshabalalisa okwethutyana gqitha. Caffeine kunempembelelo entle igazi ebuchotsheni kwaye inceda kukuphelisa ezibangela izifo. Ngaphezu koko, oko kukhuthaza nokuphefumla kunye namaziko vasomotor, likhuthaza ukwandiswa imithambo yegazi iingqameko, kuthintela zegazi esibophelelayo. Caffeine yi kukunciphisa ezigqwesileyo ukukhathala esozela. It kuphula ukusebenza yento ephilayo kunye ilizwi layo, ngoko ekuphuculeni impilo isigulane ngokubanzi. Ukudityaniswa aspirin kunye ubuncwane esikwaziyo ukuphakamisa flow igazi ifutha ngokwakhayo izitya zobuchopho.

Ezimbi apho ekulungiseleleni sifakwa

Uyacetyiswa ukuba usebenzise "Excedrin" iipilisi ze syndromes intlungu ngamandla wobulali kunye neliphakathi imvelaphi ezahlukeneyo:

• migraine;
• intloko ebuhlungu;
• neuralgia;
• lizinyo;
• myalgia, arthralgia (kabi kwamalunga kunye nemisipha);
• algomenorrhea (ubuhlungu xa esexesheni);
• syndrome bomkhuhlane.

Pharmacokinetics

Kwiimeko ezininzi, iyeza umzimba "Excedrin" ngokusengqiqweni ukunyamezeleka kakuhle. ncomo Consumer ukuqinisekisa ngokupheleleyo oku. Loo isiphumo ichiza kufuneka yeencindi:

1. I-paracetamol into ngokugqibeleleyo wendele kwi phecana zesisu. It umzimba esibindini, izintso kunye idubule njengoko glucuronide kunye sulfate conjugates. Ngaphantsi kwe-5% of zokuphuma eziphathekayo ngohlobo unmodified. Ekubeni plasma protein iqhina mncinci xa usebenzisa i idosi eqhelekileyo nezinyangayo. Kodwa ukwanda yamva - liyenyuka. metabolite Hydroxylated abunjwe izixa ezincinane esibindini phantsi kwempembelelo oxidases elingumxube kwaye zikholisa ukuba bangabi ngokuzibophelela kwi glutathione, bangaqokelela kunye libanda kakhulu paracetamol kwaye abangele nomonakalo wesibindi.
2. Acetylsalicylic iasidi ngokupheleleyo yaye ngokukhawuleza ithathe. Oku hydrolyzed kwi wokugaya, igazi kunye zesibindi. Kule fomu salicylates. Ngaphezu koko, umzimba esibindini.
3. Caffeine kwakhona ezabalazela ngokukhawuleza ngokupheleleyo. Le xiyimiso ubuninzi emzimbeni elifana neli imizuzu 5-90 emva ukusetyenziswa kwemali ungatyanga. Kukhuthaza kwenzeka ngenxa yokuba ukutya hepatic. Le into ithunyelelwa zonke neencindi zomzimba. Unxibelelwano kwiproteni plasma yi-35%. Candelo umzimba ngokupheleleyo kwaye kwazona yi nezintso.

umthamo abakwisigaba

Ezifanelekileyo zolawulo ngomlomo lithetha "Excedrin". Iyeza lisetyenziswa ngexesha okanye emva kwesidlo. Kuyanconywa ukuba usele amanzi kukuninzi.

ithamo abangatshatanga abantu abadala kunye nabafikisayo (ukusuka kwiminyaka eli-15) - 1 tablet nganye 4-6 iiyure. Ukuba umntu uba imiqondiso yokuba migraine ezayo, kucetyiswa ukuba ukusebenzisa iipilisi kanye 2. Oku kuya kuthintela kokuhlaselwa lokugula. Noko ke, umntu kufuneka akhumbule ephelisa iiyunithi ezingaphezulu kwama-6 ngosuku akuvumelekanga ngokungqongqo.

isilumkiso ebaluleke

ukuba amayeza olusebenzayo ukuba isicelo nobunzima buhlungu iintsuku ezi-3. Ngeli xesha, isigulane kufuneka udibane nogqirha wakho, ngubani na oya ukhethe indlela egqibeleleyo engenye ngazo ukulwa nezifo.

Kwezinye iimeko, isigulane Kucetyiswa ukuba ukwandisa ukusetyenziswa kweziyobisi. Kodwa isigqibo aluyo kwenziwa ngokusekelwe ezibonisa ezifanelekileyo kuphela yincutshe. Yitya iipilisi Migraine "Excedrin" iintsuku ezingaphezu kwe-3 ayikhuthazwa. Ukwandisa ithamo ekwaziyo ebangela nemiphumela emibi kakhulu. Ezifana ukonakala kwesibindi ngenxa beqokelela metabolites emzimbeni.

imiphumela emibi

Ukusetyenziswa kweziyobisi ayikwazi ngokwenene kuba nempembelelo entle emzimbeni. inani yeziphumo ebezingalindelekanga Ekubeni sele lithetha "Excedrin". analogue Drug usenokuncomela ukuphatha ugqirha, ukuba ichiza ngentla-ekhankanyiweyo ezingafanelanga ukuba isigulane.

Ngoko ke, imiphumela emibi kulandelayo:

• isicaphucaphu, ukugabha;
• gastralgia;
• hepatotoxicity;
• izilonda emathunjini ilunga kwaye wenze umsebenzi;
• nephrotoxicity;
• ziyabagulisa;
• kongeza uxinzelelo;
• tachycardia;
• nesiyezi;
• bronchospasm;
• intloko ebuhlungu;
• ukungaboni;
• ukuncipha zegazi ukulinganiswa ;
• ukuduma;
• sophele syndrome (nokopha, epistaxis, purpura);
• erythema ebulalayo exudative (okanye Stevens-Johnson syndrome);
• ukungeva;
• yityhefu epidermal necrolysis (okanye Lyell kaThixo syndrome);
• isifo sezintso (Chance necrosis papillary);
• uphuhliso abantwana syndrome Raynaud kaThixo (hyperpyrexia, lactic metabolic, ukuphazamiseka kwenkqubo luvo kunye psyche, ukugabha, umsebenzi kwesibindi engaqhelekanga).

Izimo ukuba kokufumana

Ngelishwa, asiyi kuba olusebenzayo kubantu onke amayeza. Emva iindlela lineqela Izimo. Baqinisekile ukuba ithathelwe ingqalelo phambi kokuba isicelo. Kodwa ithemba ukuba iyeza akwenzeki ngaphandle kweendleko. Ugqirha nokuya Kulula kakhulu ukuba indawo isixhobo "Excedrin". Analogs ukuvumela ukuba kuzuzwe iziphumo ezamkelekileyo.

Iyeza contraindicated kule ezimbi zilandelayo kunye nemiqathango:

• Hypersensitivity ukuba izithako;
• izilonda emathunjini kwinqanaba oyingozi;
• isifuba inyumoniya,
• ukopha zesisu;
• polyposis nezolo ngeempumlo (sinuses paranasal);
• nobandlululo ku NSAIDs;
• Iinkqubo zotyando ezihamba ukopha;
• sophele diathesis;
• wegazi;
• kubazali bakhe;
• gipoprotrombinemii;
• BP portal;
• glaucoma;
• ischemia kakhulu intliziyo;
• K beriberi;
• ukungabikho glucose-6-phosphate dehydrogenase;
• ukusilela kwezintso;
• nokukhulelwa;
• zisanyisa;
• zokulala;
• ucaphuka;
• yobudala yabantwana (ichiza asisebenzi kwiminyaka 15).

libanda, yamayeza

Medicine "Excedrin" migraine kufuneka zithathwe kuphela ngeedosi kubonisiwe apha ngasentla. Ekubeni arhente kakubi inokukhokelela inkitha iimpawu ezingemnandi.

Malunga libanda of paracetamol lubonisa mpawu zilandelayo:

1. Ebudeni ngosuku lokuqala apho lipholi ulusu, ukugabha, isicaphucaphu, iintlungu esiswini, nokuphazamiseka glucose ukutya, ukudla, lactic metabolic.
2. Emva kweeyure 12-48 zokusebenza zimpawu kunokwenzeka wa sisibindi ivakalise kunye ukuqhubela phambili Encephalopathy. Kuba nzima kakhulu libanda, kunokwenzeka - isiqaqa nokufa. Kusenokubakho ukusilela kwezintso, ephelekwa necrosis tubular, pancreatitis, arrhythmia.

Libanda, nomsindo acetylsalicylic acid, ine mpawu zilandelayo:

1. Enomoya - ukugabha, isicaphucaphu, isiyezi, ukungaboni, ukuduma, intloko ebuhlungu.
2. Ukonakalisa kakhulu - ukuphelelwa umoya, cyanosis, dyspnea, umbilo encangathi kuyabanda, lactic yokuphefumla, ukukhubazeka sokuphefumla.

Abuse okubangelwa caffeine kubonakaliswa ezi mpawu zilandelayo:

• gastralgia;
• kukuphazamiseka, ixhala;
• ukudideka;
• Mzoli;
• emzimbeni;
• arrhythmia;
• Ukuchama rhoqo;
• tachycardia;
• komzimba;
• anda intlungu kunye novakalelo;
• lafa;
• unkenteza ezindlebeni;
• isicaphucaphu, ukugabha (ngamanye amaxesha kunye ubukho igazi);
• sokuwa.

Ukuba libanda, kufuneka ufune uncedo lonyango olungxamisekileyo. Ngexesha iiyure zokuqala 4 kucetyiswa ukuba uhlambe isisu, ukuzama ukumgabhisa. Laxatives kufuneka osetyenzisiweyo kwaye lithetha "carbon kwasebenza".

analogue iyeza

Khumbula ukuba naliphi na ichiza kufuneka amiselwe ngugqirha, ekubeni-arhente nganye kuyabonisa zayo Izimo.

Kwaye kuphela ugqirha uyakwazi endaweni enye amayeza iziyobisi "Excedrin". Analogs ye candelo yangoku ngolu hlobo lulandelayo:

• "Akvatsitramon".
• "Atsifein".
• "Askofen".
• "Kofitsil plus."
• "Tsitramarin".
• "Migrenol Extra."
• "Tsitramon".
• "Tsitrapar".

Iindleko ichiza

Ngokuba konke ukusebenza kwalo, iindleko amayeza engaxabisi kakhulu kubasebenzisi "Excedrin" evela uqaqanjelwa. Price of iphakheji (tablets 10) kuyahlukana ku ezahlukene 120-150 engange. Iindleko ukulungiselela iipilisi-20 ka-210-250 engange.

Unxibelelwano namanye amachiza

Izigulane abathatha ichiza "Excedrin" kufuneka iqondwe ukuba nokukhuthaza ifuthe emzimbeni ezinye iindlela ezifana:

• "LweeHedfowuni";
• anticoagulants ngqo;
• "Reserpine";
• iziyobisi hypoglycemic;
• iihomoni steroid.

Qaphela ukuba ukusetyenziswa ngaxeshanye kwemali "Excedrin" kunye nezinye NSAIDs kunokubangela iziphumo ebezingalindelekanga. Umzekelo, intsebenziswano kunye iziyobisi protivopodagricakih, iziyobisi umfutho, lithetha "Furosemide" kukhokelela kucikizeko aphantsi kula maqela iziyobisi.

umbono kwabathengi

Nayiphi chiza (akukho Ngaphandle ngezinto ezibotshwayo "Excedrin") iimpendulo, kuzo ebezintle nezo zingentle.

Abanye abathengi Ndithi ngeliphandle ukuba, akuba wazama ichiza kanye, angeke inxalenye nabo. Baninzi iluncedo ebhegini yakhe. Ngokuba umntu akalazi uhlaselo neentlungu zikufumane. izigulane ezinjalo phawula ukuba elinye icwecwe lixa ekwaziyo ukuphelisa iimpawu ezingemnandi. Kwaye kwimeko uqaqanjelwa kakhulu ephelisa intlungu iipilisi namayeza 2 "Excedrin". Iimpendulo abonisa ukuba ukusebenza ogqwesileyo isixhobo.

Ezinye abathengi ubambe kwindawo ezahlukeneyo lwembono, bexela ukuba lilize ichiza. Bathi ukuba izinto esebenzayo amayeza zingathengwa ngamnye kutshiphu kakhulu ekhemesti. Nangona kunjalo, ezi abathengi ukulibala ukuba ngempumelelo ichiza kwaba ngenxa indibanisela ilungelo labo bonke izakhi ezihlobeneyo enye ngokupheleleyo.