C-peptide namanqanaba insulin

C-peptide - iintlobo inxaxheba ekumisweni insulin. Le yinxalenye molecule proinsulin. Insulin - Xa C-peptide ke wanamathela ukusuka kwemolekyuli proinsulin, kukho izinto ezintsha ivela njenge yoko. Le yamasuntswana, ezifana insulin, ukuze abe igazi lomntu. Noko ke, sokonakalisa izibonelelo kwacotha ngaphezu yokubola insulin, ngoko ke umlinganiselo phakathi kwezi zinto zimbini egazini ilingana 5 1 wakhetha insulin. Kwaye ke ngempumelelo kakhulu ukuthatha uhlalutyo C-peptide egazini kunokuba insulin.

C-peptide - kukho izinto eziphilayo engasebenziyo, yaye enyanisweni udlala nje indima - ekumisweni insulin. Iiseli proinsulin kukho iintlobo ezimbini ezingundoqo peptides - A no-B lebhokisi kuzo kunye nabanye wesithathu, S. C. Ngokukhawuleza kuphambuka A and B, usenziwa insulin. Enyanisweni, lo linchpin, leyo sdergivaya kunye proinsulin, ukunika hormone oyifunayo. Oku kubonisa isixa insulin C-peptide. Eqhelekileyo ukuzila oko isusela ku-0, 53 ukuya 2, 9 ng / ml. Phakathi Izixamali zezi zinto, kukho unxulumano ngqo. C-peptide siyandiswa - ngoko, kunye insulin ukwanda. Ngaphezu koko, ukuhlaziywa peptide-kuqaliswa ngokuzenzela ukunceda umahluko insulin eveliswe umzimba. Ngokungafaniyo hormone kubalulekile, nto leyo ke kuyimfuneko ukuba processing glucose, C-peptide akazalani receptors isibindi, yaye ejikelezayo ngayo kwi xi efanayo Kwangale portal. Kwakhona, ihlaziya oko kunokwenzeka ukuvavanya imeko β-leseli injeke sabantu seswekile aphathwe ngendlela insulin zamntu eyaziswa emzimbeni. Kwakhona mvavanyo ziya kuqinisekisa nokuhlalutya ukuhla kumanqanaba insulin ngexesha kulibaziseka layo esibindini.

Kwaye ngoku ngakumbi kancinane. Proinsulin lukhutshwe iiseli beta pancreatic. Ngaphezu koko, le nto waphula waya into yokuba kule ngongoma phantse Akuyomfuneko umzimba womntu, kwaye loo hormone ebalulekileyo. Noko ke, unako uthelekise ezi izinto ezimbini kunye nezalamane esisondeleyo abathathi ngaphandle omnye komnye. Apho C-peptide kunye insulin apho, kuba zombini zenziwa ukwimo enye. Kungenxa yoko le nto inani C-peptide ngumlinganiselo yomsebenzi kunye iiseli beta kunye namanqanaba insulin emzimbeni. Ukuba ngenxa yezizathu ezithile ezingaziwayo, amajoni omzimba aqale ukuhlasela kwi iiseli inxaxheba kwimveliso insulin, kule meko ukufumana i seswekile yenqanaba lokuqala. Ngamanye amazwi, iswekile yegazi oluhlala ngakumbi nangakumbi, kodwa oko akuthethi ukungena kwiiseli, njengoko "isitshixo" ngenxa ukuba iiseli na insulin, leyo, yeha, ayisa zaveliswa. Ukuba iiseli ngenxa yaso nasiphi na isizathu, musa ukuthobela iziganeko kwale hormone, ngoko, ngathi, iingcango yeseli aliyi kuvulwa, yaye musa ukudlula iswekile. Kulo mzekelo, kwinqanaba lesibini kubonakaliswa seswekile. Lo mfanekiso efanayo - amanqanaba iswekile yegazi ngcembe uqala ukuya off akhasayo, kwaye ukubeka oku glucose ukuba, ngenxa yokuba akwazi ukufumana iiseli abakwazi. Kudla luphawu ezaziwayo-kakuhle insulin banda, Noko ke, oko kuncitshiswa kule meko.

Iiseli musa uve umqondiso omnye iihomoni ezibalulekileyo zepancreas kakhulu kungenxa yokuba kukho kukwaphula izinto ezibangela ukutyeba. Kungenxa yesi sizathu ukuba seswekile ngumphakamo wesibini nangoku elikholisa ukubizwa ngokuba 'nabantu abatyebe seswekile. " Xa diabetes level kwenqanaba ka C-peptide ingaphantsi eqhelekileyo seswekile kwinqanaba lesibini ukwimo mkhulu kunaye kuyimfuneko. Ngoko ke, kwimeko yokuqala akukho insulin, ngoko glucose Awukwazi ukungena kungena iiseli. Okwesibini - oko kukuthi, yaye eninzi, kodwa iiseli musa baphulaphule, njengokuba glucose awukwazi ukungena kwiiseli. Ngamanye amazwi, izinto apho kuyimfuneko umsebenzi zeselula, ukuba ingafikeleleki kubo. Yaye kutheni diabetes - njengoko sisifo esibi.

Inqanaba C-peptide zancitshiswa okanye banda ngaxeshanye kunye kumgangatho insulin. Ukuba le salathisi kwi igazi ekhoyo hi mpimo enganelanga, ulawulo hormone nayo understated. Kwelinye icala, xa C-peptide yi kakhulu, loo nto kusenokwenzeka icebisa ukuba insulin nokunyoluka. Kukho izizathu zokusilela kwenkqubo, kunye iihomoni agqithisileyo, ebonelela iiseli ngamandla, kwaye azisoloko ezinxulumene ne seswekile. Kudla ukuba C-peptide nalo ngaphezulu kunesiqhelo ngenxa insulinoma okanye insufficiency sezintso ngendlela ezigulo ezondeleyo. Kaloku, ukuncipha wayo amaninzi wabangela ngenxa seswekile.