Zokuma: uphengululo amayeza, kunye nokusebenza neempendulo

arhente Cardiotonic iziyobisi ukwandisa umsebenzi umsebenzi kwemisipha intliziyo, ukukwazi layo contractile kwaye esetyenziswa ukunyanga isifo senhliziyo. Eli qela ubandakanya isixa esikhulu kweziyobisi kunye zizinto esebenzayo ezahlukileyo ukwakhiwa kunye nendlela eyahlukileyo amanyathelo. Cardiotonic esetyenziselwa unyango iifom oyingozi futhi esingapheliyo ukuphanza kwentliziyo.

Zokuma: ngezigaba

Isiphumo lilonke onke amachiza kweli qela, ngokusekelwe ukukwazi ukwandisa amandla ucutheko engabalulekanga, ukuze kwandiswe ukusebenza ezesifuba imveliso kunye stroke umthamo wegazi. arhente Cardiotonic ukunciphisa umthamo ukuzala, yemiphunga nezengekho noxinzelelo systemic lwemithambo, yaye ingcinezelo ngexesha ukuzaliswa ventricles.

1. glycosides senhliziyo - "Strofantin", "Korglikon", "digoxin".
2. amachiza Adrenergic - "Izadrin", "Dobutamine", "Dopamine".
3. iziyobisi zokwenziwa Adrenergic - "Amrinon", "Milrinone".

iziyobisi yokukhetha esetyenziswayo ezinxulumene ne ubukhali imeko yomguli kunye uhlobo khosi isifo.

glycosides inhliziyo

Le Group imelwe ngokusebenzisa zemifuno okanye imvelaphi zokwenziwa. Imixube esekelwe izinto ezivela digitalis yezityalo, goritsveta, intwasahlobo oyinyibiba, oleander, strophanthus et al.

Ubude amanyathelo unyango, isiphumo sokuzuza emzimbeni, kunye neziyobisi neurotoxicity zixhomekeke ngokupheleleyo ngokukwazi ukwenza izakhiwo kunye iiproteni plasma. Luqine uqhagamshelwano olunjalo, kokukhona ukusebenza kakuhle glycoside. Wentliziyo eli qela kufuneka isenzo ngokusekelwe ezi ndlela zilandelayo:

• okunciphisa systole kwenzeka ngaxeshanye inzuzo yayo;
• ixesha lokuphumla le izihlunu intliziyo elide;
• lehla izinga intliziyo;
• umsipha engabalulekanga nokukhulisa amandla excitation;
• Ukuba libanda, iyakhula fibrillation ventricular.

"Digoxin"

Ichiza kuhlelwe ukusuka amagqabi digitalis. Oku kubhekisela glycosides elide-ngokwenza, hayi ukunika iziphumo zazo emva kodlwengulo. Isetyenziselwa unyango entsonkothileyo ukusilela intliziyo ezingapheliyo kunye arrhythmia tachysystolic.

Ifumaneka njengoko iipilisi kunye nesisombululo injectable. Ithamo kufuneka zikhethwe ngononophelo ukuze isigulane ngamnye. Kwimeko yezinye glycosides kwentliziyo phambi 'digoxin' liyancipha balawule.

"Strofantin"

glycoside wentliziyo mifutshane-acting, esetyenziswa kwimeko iintlobo nokoyika sifo. "Strofantinom" ayikho eziziimpawu yande emzimbeni. Amalungiselelo kuphucula umsebenzi contractile le myocardium kunye nokwandisa imveliso intliziyo. Ngaxeshanye, kukho ukwehla kwi ubungakanani imisipha yenhliziyo nciphisa imfuno yayo oksijini.

Alawulwa ngurhulumente yegazi, intramuscularly, kwezinye iimeko - ngaphakathi. Ukusela izixa ezikhulu kunokukhokelela ukuba libanda. Ukusetyenziswa namanye amachiza Ndiyijike ngokugqibelela glycoside:

• ukusebenza barbiturates kuyehla;
• with "reserpine", sympathomimetics kunye lakhula kunokubangela uphuhliso arrhythmias intliziyo;
• ukwamkelwa kunye tetracyclines, "chloramphenicol", "Amiodarone" yaye "captopril" kudandalazisa amanyathelo intliziyo;
• magnesium sulfate ikhuthaza intliziyo atrioventricular block.

iziyobisi adrenergic

Neglikozidnye arhente cardiotonic ukuba inyathelo elifutshane. Iqela ezisetyenziswa ngexesha nokoyika ukusilela intliziyo ukuxhasa imisebenzi ebalulekileyo umzimba.

"Izadrin" yi ivuselela izitya adrenergic, bronchi nentliziyo. Eli chiza kunempembelelo iqinile, kwandisa ubuchule contractile kwemisipha kwentliziyo. Used in contractility kwentliziyo kunye ukuhla elibukhali kwimisebenzi yokusebenza, ngokunjalo yokothuka cardiogenic. Izimvo oogqirha zilumkisa ukuba isicelo ephosakeleyo okanye ngeedosi kwemfuneko kunokubangela fibrillation ventricular kwentliziyo.

"Dobutamine" - Isakhiwo neglikozidnye cardiotonic, ibe nafuthe emnandi imisipha yenhliziyo normalizing igazi sentliziyo. Ingozi arrhythmias xa usebenzisa esi sixhobo iphantsi kakhulu, ngenxa yokuba "Dobutamine" liye phantse akukho alunasiphumo kwi ukuzenzekela intliziyo.

Eyabelwe ukuphucula contractility le myocardium ngexesha kuyimfuneko ekhawulezileyo. Kwezinye iimeko, oku kungabangela uphuhliso yeziphumo ebezingalindelekanga:

• isicaphucaphu;
• intloko ebuhlungu;
• wegazi;
• tachycardia;
• ubuhlungu emva breastbone.

"Dopamine" i catecholamine ekhuthazayo nezamkeli adrenergic. Ichiza uphakamisa uxinzelelo lwegazi, kwandisa ukuhamba kwegazi sentliziyo. Oku kuboniswa ngokusilela etsolo engabalulekanga, ukothuka. Isilumkiso kufuneka zisetyenziswe iposi engabalulekanga, ukukhulelwa, isifo lengqula, arrhythmias.

cardiotonic Adrenergic zokwenziwa

Oku kusetyenziswa xa insufficiency coronary ludlule, izibonelelo inhliziyo. Iziyobisi sithathele contractility kwemisipha intliziyo, ukwandisa oko. Engabangela uphuhliso arrhythmias, lisibekele uxinzelelo lwegazi, ukuphazamiseka le sezintso.

amachiza wentliziyo kweli qela ayikwazi ingasetyenziswa abaneziphene ngentliziyo, kwakunye cardiomyopathy, ukuphazamiseka isingqisho kwentliziyo, kwemithambo aortic, ukusilela kwezintso, isifo sentliziyo kunye ngexesha nabantwana.

Lithetha "Amrinon" isetyenziswa kuphela xa ICU, isigulane eyayigcinwe ngaphantsi kolawulo izixhobo ezikhethekileyo, ebonisa isimo sayo. Ukongezelela ukwandisa ukulungiselela izinga intliziyo esandisa imithambo yegazi, kwandisa ejection igazi ngexesha systole kunciphisa uxinzelelo miphungeni.

It yaveliswa isisombululo. Kuba efakwa sobisi kakhulu isisombululo sodium chloride nokomzimba. Ngaba ukuxutywa kunye nezinye iziyobisi. Yokusungulwa kunokwenzeka ukuhla elibukhali uxinzelelo, ukwanda izinga intliziyo, arrhythmia, intloko ebuhlungu, ukuphazamiseka zesisu.

"Milrinone" iyasebenza ngaphezu ummeli lokuqala qela, ndiwavuze izimvo ukunyamezeleka ngcono zizigulane. Contraindicated ukusetyenziswa amayeza ngexa lokukhulelwa kunye nophuhliso iposi engabalulekanga. Oku kuquka amalungiselelo kwiqela A. Imfuno mali kuxhomekeke kuphela ngugqirha wakho.

isiphelo

Wentliziyo kwaba ukusebenza izizukulwana embalwa edlulileyo. Ukuphonononga zibonisa ukuba eli qela amayeza ukunceda ukuhlangabezana nokusilela ngentliziyo. Nangona kunjalo, ukuthatha la mayeza ngohlobo self-unyango esokuba contraindicated ngenxa yeengxaki kunokwenzeka, iziphumo ebezingalindelekanga okanye libanda. Ukhetho kweziyobisi, kwakunye ithamo ukwamkelwa cardiologist simisela kwimeko nganye clinical ngamnye.