Ukususela oko esiza, "famotidine"? Imiyalelo yokusebenzisa, real

Ngaba uyazi ukuba yintoni esiza "famotidine"? Phendula ku ungakwazi kuphela ugqirha lo mbuzo. Ukuba ixesha kokubonisana nogqirha akwenjinjalo, ngoko siza sithethe ngayo kweli chiza kweli nqaku.

Uza kufunda iimpawu uthe medicament, njengoko lumile, oko izifo isetyenziswa, Yintoni efakiweyo kumafa yawo, njalo-njalo.

Ukwakhiwa zizinto ebekupakishwe iziyobisi, kunye nenkcazo ifomu

Ziziphi ukukhululwa medicament "famotidine" ifomu? Manual ithi esi sixhobo zifumaneka ngohlobo iipilisi. Zinelungelo imilo lenticular setyhula, kwakunye umboniso camera luthuthu ngebala okanye omthubi.

Yintoni na izithako ibandakanya "famotidine 'iziyobisi? Ukubunjwa ichiza ilula: eyona nto iphambili - famotidine. Ngaphandle izinto isiseko, sisixhobo ziqulathe inkxaso, ezifana neselulosi microcrystalline, umbona starch, nemagnesium stearate, talc, lesilicon dioxide kunye ne croscarmellose.

Ngokuphathelele amacwecwe, oko kuquka macrogol 6000, hypromellose, talc, titanium dioxide kunye nentsimbi oxide umbala omdaka.

Iyeza yokuthengisa ingqalelo iza Imiqulu blister, ezo zahlanganiswa ukuphakheja ephepheni.

Kufuneka kugxininiswe ukuba ulungiselelo "ye famotidine" apho umyalelo iboniswa ngezantsi, iveliswa ngeedosi ezahlukeneyo - mg-40 no-20.

Iimpawu beziyobisi

Ngaphambi kokuba siphendule lo mbuzo oko kwenza "famotidine" kufuneka usixelele ukuba isebenza njani na ichiza. Ngokutsho imiyalelo, i-arhente lwezifundo a blocker of receptors H2-histamine. Ibonisa iipropati anti-isilonda.

Eyona nto ephambili ichiza zinegalelo kwezithandani imveliso acid carcinomas (zehydrochloric acid) esiswini. Ngaphezu koko, famotidine lunciphisa ukukhuthazwa histamine, acetylcholine kunye gastrin kunye juice esiswini kwandisa pH, umsebenzi pepsin kwaye kunciphisa ukwenziwa HCL.

Ngenxa yokwanda le inqanaba glycoprotein Ukwakheka kuthetha ukunyuka yencindi esiswini nokukhuthazwa prostaglandin yokuqaphela. Esebenzisa secretion hydrogen iphunyelelwe kwaye kombisaka inxeba ephilisa iimpawu ichiza.

amayeza kujongwa onqanda ukopha ukususela esiswini, ephilisa umonakalo kwi uxakaxa yayo nezibhaxu izilonda uxinezeleko.

Iimpawu ichiza

Ukulungiselela "Famotidine" (iziyobisi ixabiso analogs ezidweliswe ngezantsi) siqala ukusebenza encinane kwinkqubo ibinzana (oxidase) enzyme cytochrome P450 esibindini.

ukusebenza kwalo eli chiza luqala emva kwemizuzu engama-65, oku kuthatha malunga ngemini.

Le kinetics ka iziyobisi

Le medicament "Famotidine", ogama reading zichaziwe apha ngezantsi, emva ulawulo ngomlomo ifunxwe ukusuka emathunjini. ingqondo (ubuninzi) igazi layo afunyenwe kwisithuba seeyure ezintathu.

Unxibelelwano kweziyobisi kwiiproteni plasma 15-20%. It salawo ngobisi sikanina kwaye ingene nge njengomqobo placental.

Malunga nama-30-35% ukwimo iziyobisi esebenzayo ethathelwa ingqalelo umzimba esibindini. Oku kwenza S-oxide.

Ukuphelisa isixhobo kwenzeka ubukhulu becala ngenxa nezintso. Malunga nama-27-40% beziyobisi esiswini saso umchamo ngohlobo ingaguqukanga. isiqingatha-ubomi 'of famotidine "ixesha ziiyure 3-4. Abantu abane CC ngaphantsi kwama-30 ml ngomzuzu le yesalkathisi olwandisiweyo iiyure 11-12.

Ukususela oko kunceda "famotidine"?

Kwezinye iimeko, ingxelo amayeza amiselwe ngugqirha? Ngokutsho imiyalelo, ukufumana ezibonisa oku iziyobisi lithi zilandelayo:

• inkqubo mastocytosis;
• uhluleka zokuthintela, yokusila isifo elithi isilonda;
• reflux esophagitis;
• gastro ilunga;
• ukuthintelwa uhluleka, ezo ezinxulumene nokusetyenziswa elide NSAIDs;
• syndrome Zollinger-Ellison;
• ukuqunjelwa functional, nto leyo inxulunyaniswa wona umsebenzi (secretory) esiswini;
• izilonda emathunjini, xi lingaze;
• Prevention of ngeminqweno juice esiswini kwi iziguli utyando phantsi zomzimba ngokubanzi (ngamanye mendelson kaThixo syndrome);
• adenomatosis ezidalwe multiple;
• uthintelo ukuphinda ukopha, kuquka ixesha post-operative;
• Uthintelo yokulangazelela pneumonitis;
• neuralgia ne intlungu intlungu retrosternal okanye epigastric ukuba kwenzeka ebusuku okanye enxulumene kunye nokudla ukudla okuthile.

Siphelisa imithi ukusetyenziswa

Ngoku uyazi, ukususela oko inceda "famotidine". Kodwa ngaphambi kokuba uthathe le amayeza, kufuneka uziqhelanise wena kunye nemiyalelo. Le iyeza contraindicated ukwamkela kwi:

• zisanyisa;
• kubantwana abangaphantsi kweminyaka emithathu ubudala (ubunzima bomzimba ngaphantsi kwama-20 kg);
• yokumitha;
• hypersensitivity ku famotidine, ezinye blocker kunye H2-histamine receptor.

Ngononophelo olulodwa uthe amayeza esimiselweyo insufficiency hepatic okanye kwezintso, omzimba, isibindi ukuqina kunye Encephalopathy portosystemic ebantwaneni.

Indlela ukuthatha 'famotidine "?

Olu nyango emiselweyo ngaphakathi. Musa ingawutyisi iipilisi, wabahlamba phantsi kunye mali olwaneleyo ulwelo.

Abadala ingqalelo ichiza kufuneka onyule kuphela ngugqirha (ngokuxhomekeke kubungqina).

Xa isilonda ye phecana wokudla, ingakumbi kwisigaba etsolo kwakunye nangezilonda, lingaze gastroduodenite ilunga medicament esebenzayo isincomo ukuthatha 20 mg kabini ngemini, okanye kanye xa isixa-40 mg (ubusuku). Ukuba oyifunayo, idosi yemihla ngemihla ichiza anokuthi alungi-lungiswe kwaye landile ukuya 80-160 mg.

Ubude unyango le arhente ziiveki 6-8.

Kuthintelo lwe kwethumba likakade iziyobisi "Famotidine" Izimo leyo kuluhlu, 20 mg elawulwa kanye ngemini, ebusuku.

Xa ukuqunjelwa, nto leyo ehambisana nokonyuka secretion esiswini, iyeza Kucetyiswa ukuba kwi idosi enye.

Ukuba kukho refpyuks iyeza oesophagitis esetyenziswa kabini ngosuku 20-40 mg iiveki 6-12.

Ukuthintela ngeminqweno juice esiswini phantsi zomzimba medicament jikelele ibhalwa isixa-40 mg ngokuhlwa okanye ngokukhawuleza phambi uqhaqho.

Xa Zollinger-Ellison syndrome oyidlayo kunye nobude isicelo zawo zibekwe ngamnye. Ngokuqhelekileyo, ithamo lokuqala isiyobisi 20 mg. Thatha le iyeza kufuneka ube zonke kweeyure ezintandathu. Ukuba kuyimfuneko, isixa medicament ukuze kwandiswe ku 160 mg amaza reception okufanayo.

Xa kukho ukusilela kwezintso (umz, CC ngaphantsi kwama-30 ml ngomzuzu) yonke imihla iindlela umthamo kufuneka zancitshiswa mg-20.

Nomthamo kubantwana

Ukususela oko kunceda "famotidine 'abantwana? Oku kuthetha ukuba abantwana wabelwa ngenxa yezizathu efanayo abadala. GI isilonda ngendlela kwisigaba exacerbation, yaye reflux esophagitis Kucetyiswa ukuba athathe amayeza ngokwezi nkqubo zilandelayo: 2 mg ngalinye 1 kg ubunzima bomzimba ngosuku. Le mfumba ichiza izigaba ezibini.

imiphumela emibi

kuthetha Izincomo inokubangela iziphumo ebezingalindelekanga ezifana:

• umlomo owomileyo, arrhythmia, isicaphucaphu, amaqhakuva vulgaris, ukugabha;
• alopecia, iintlungu esiswini, isikhumba owomileyo, ukuqumba, sinciphise uxinzelelo lwegazi, ukuqhina;
• irhashalala eluswini, urhudo, AV-block, ukuphazamiseka ukutya, angioedema;
• hepatitis, ukurhawuzelela, enzayim isibindi ophakamileyo, Njengokungeniswa anaphylactic;
• pancreatitis etsolo, iimpawu hypersensitivity, intloko ebuhlungu;
• bronchospasm, isiyezi, nokushisa, sokulibala, paresis yokuhlala;
• bradycardia, ixhala, ukudideka, ukuduma, vasculitis;
• leukopenia, ukudinwa, kumanqanaba urea igazi, nemibono, agranulocytosis, ukozela;
• thrombocytopenia, ukudakumba, hypoplasia, uvalo, pancytopenia, ukugula ngengqondo;
• bone lomongo aplasia, ukungaboni, hyperprolactinemia;
• ifiva, ukuphelelwa yobuntu, amalungu abe buhlungu, gynecomastia, namandla, amenorrhea, nobuhlungu bomzimba.

Ixabiso kunye analogue

Indleko yale yemveliso "famotidine" imalunga 30-55 engange. Ukuba kuyimfuneko, oko kufakwe nucleoside ezifana "Gastromaks", "Kvamatel", "Gastrotid", "ulfamid", "Famozol", "Famodingeksal", "Famosan".

Reviews imithi

Drug "famotidine" - i-arhente ethandwa kakhulu anti-isilonda. Izigulane bathi ngokuphumelelayo esizibonakalisa izifo ezinxulumene ne iphecana zesisu. Amaxesha amaninzi oko ezimiselweyo gastritis kunye nezilonda.

Enye inzuzo yalo ichiza cheapness yayo isalamane.

Njengoko ngokuba ncomo ezimbi, ngoko ke izikhalazo aqhelekile malunga kwiziphumo ebezingalindelekanga zeyeza.