"Pentoxifylline": analogue, imiyalelo ukusetyenziswa, amaxabiso real

Ichiza na indawo "Pentoxifylline?" An Togu beziyobisi kuya kwenziwa izinto nqaku. Kuwo uya kufunda oko kuthethwa uthe iifomu medicament apho wathengisa ngayo, kufuneka isetyenziswe ngayo, njalo-njalo.

Ekwakhiweni, imilo, ukupakishwa

Ziziphi fom kuthengiswa iziyobisi "Pentoxifylline?" Imiyalelo yokusebenzisa (analogue eli chiza inokufumaneka nayiphi na ivenkile) lubonisa ukuba iyeza iyafumaneka ngeendlela ezahlukeneyo, ezizezi:

• Emacwecweni (400 no-100 mg) ziya camera pink. Xa elinye ibhokisi iqulethe iziqwenga 60 okanye 20.
• Le zithutha (400 no-100 mg). Umqulu odiyo ikhadibhodi inokuba iziqwenga-60 okanye eli-20.
• Emacwecweni, isenzo elide (600 no 400 mg) ziya wawutyabeka kwaye ama-wawutyabeka babe umgca hlukana. Ibhokisi ezingxobeni ngokuqhelekileyo iqulethe iziqwenga-50.
• Ezineengqayi ngesisombululo ukuba isitofu. Ukwakhiwa kwale kuqulunqo iquka pentoxifylline kunye sodium chloride kunye namanzi.

features kwemithi

Ziziphi iimpawu ntoni ichiza "Pentoxifylline?" Togu yale ndlela neneempawu ezifanayo njengoko watshoyo medicament yedwa. Ku fanele a amayeza mali omtsha iqela hemorheological kuyo. Uyakwazi ukubuyisela plasticity iiseli ezibomvu zegazi nokunciphisa deformation zabo. Oku kwandisa permeability kwemithambo yegazi, apho kukho mithambo elimxinwa.

Ezi iimpawu ichiza kukhokelela ekuphuculweni microcirculation, nemiphumo emihle kwezihlunu hypoxia.

wenza njani "Pentoxifylline?" Analogue sokungenisa kunye Russian kuba luncedo enyangayo efanayo naleyo imali ngokwayo. Emva ukusetyenziswa kweziyobisi, nto lunciphisa udibaniso lwe erythrocytes leyo kamva ngokulula ukwandisa igazi kuqukuqela Amalungu angene kungena ulwalathiso extravascular.

Asinako ukuba ichiza ingqalelo kunciphisa viscosity igazi, ngaloo ndlela ikhuthaza zegazi ahlazululwe. Ngenxa yemiphumela beziyobisi Ekwandeni umzuzu kunye nomthamo nobetho, kodwa oko akuthethi ukutshintsha amanani izinga intliziyo.

Ngenxa yoko, isitya ukwanda kwemiphunga kuphucula O ₂ umxholo igazi, kunye nokwandiswa nemithambo yenhliziyo ukwandisa O ₂ nokusiwa kwawo myocardium.

ekuqulunqeni kujongwa ekwaziyo ukunyusa ithoni izihlunu bokuphefumla uvalo. Phantsi impembelelo yayo kwandisa umthamo wegazi lowo ujikeleze lonke collaterals, kwakunye eyomeleziweyo igazi ukuhamba kuzo.

Ziziphi ezinye iinkalo chiza "Pentoxifylline?" Togu kweli chiza kwaye ichiza ngokwayo ukwandisa uyondelelwano lwee- ATP ebuchotsheni kwaye kuphuculwe unikezelo igazi kwimimandla ezonakeleyo (umz; xa stroke kobuchopho).

Kufuneka kuqatshelwe ukuba ichiza uthe inempembelelo entle kwinkqubo luvo kunye nokusebenza kwayo. Xa izitshanguba ezincinane yoluvo usebenzisa oku kuthetha kukhokelela yokonyuka imigama ukuhamba, kuquka nezifo ezifana endarteritis obliterative.

pharmacokinetic iparameters

iziyobisi "Pentoxifylline" Kusekude njani? Imiyalelo yokusebenzisa (analogue iyeza ezidweliswe ngezantsi) usixelela ukuba eli chiza inamandla kakhulu gaze, kubandakanya njengomqobo segazi lobuchopho.

Kwisiqingatha ubomi ichiza xa ilawulwa yegazi banemizuzu engama-30. Xa ekufumaneni ichiza ngaphakathi ako ngokupheleleyo iphecana zesisu.

Medicament aguqulwe esibindini, apho akha metabolites theobromine. Igazi xi liphezulu ichiza iyazalisekiswa kwiiyure-4 emva kokuba isicelo. Noko ke, lona luhlala kumanqanaba zonyango yangathi yimini.

medicament neboniswe izintso (malunga nama-95%). emathunjini ngokusebenzisa amayeza ngaphandle kancinci.

Ngelo besini wamhle abo ibele, ichiza nga akhululwe kunye nobisi. Kufuneka kuqatshelwe ukuba kubulawe beziyobisi kwathotha kwizigulane kunye nesifo sezintso kakhulu, isibindi kunye nabantu abadala.

Ubungqina obubonakalayo buxela ukuba ukusetyenziswa

Kuba yintoni iinjongo isigulane linokukwenziwa ukuba amayeza "Pentoxifylline?" Analogs nawethutyana, ichiza kufuneka okukhomba efanayo.

Njengangoku, ichiza enjalo isetyenziselwa ukunyanga izifo ezininzi. Apha ke ngoku:

• intswelo cerebrovascular;
• urolithiasis;
• arteriosclerotic Encephalopathy;
• stroke kobuchopho;
• nefroangiopatiya abaneswekile;
• wegazi;
• kwemigudu obstructive;
• isifuba inyumoniya;
• izifo kwegazi neuropathy ;
• Encephalopathy;
• algomenorrhea;
• nokudumba;
• cholecystitis;
• zeDyskinesia isisu ;
• pilorospazm;
• spasm umsipha ziindlela ezigudileyo;
• syndrome post-trombophlebitic;
• seTrojan;
• angioneyropatii (isifo Raynaud yakhe) ;
• izifo yegazi eye;
• ukuphazamiseka zeethishu trophic;
• izilonda trophic;
• ukusongela isisu;
• ukuphazamiseka komsebenzi we phakathi nendlebe engaphakathi;
• induku yegazi;
• muscular dystrophy;
• ekuboleni, frostbite.

Izimo

Zeziphi izifo abavumelekanga ukuba usebenzisa iziyobisi "Pentoxifylline?" An Togu beziyobisi kunye ichiza ngokwayo ingenakuthatyathwa abantu abane ukunyamezelana ukuba iinkalo eziphambili, kwakunye nezinye izithunywa iqela xanthine le.

Ukongeza, ichiza ingqalelo contraindicated kwizigulane abasanda wabethwa stroke ukopha okanye iqhosha etsolo engabalulekanga kwakunye ukubandezeleka entliziyweni kakhulu yegazi kunye nemithambo ebuchotsheni, porphyria.

ukusetyenziswa kweziyobisi efakwa engaqondanga ukuba arrhythmia, ukopha, libya uxinzelelo lwegazi, hemorrhages kwiretina. Kwakhona, ichiza contraindicated ngexesha zisanyisa kunye kokumitha, nabantwana ukuya kwiminyaka eli-18.

Ngononophelo olulodwa wabelwa kuthetha abantu abasebenza (ukuze kuthintelwe ukopha of inwebu yangaphakathi kwaye amalungu zangaphakathi), kwaye izigulane sezintso kakhulu kwaye wesibindi, isifo isilonda emathunjini, gastritis kunye ukusilela intliziyo.

Indlela Yokusebenzisa

Indlela yokusebenzisa iziyobisi "Pentoxifylline?" Imiyalelo yokusebenzisa, yokwenene (analogue esi sixhobo inokuba iidosi ezahlukeneyo) oogqirha abanamava bathi eli chiza kuthathwa ngomlomo kwaye parenterally (ngokuxhomekeke nobungozi besi sifo).

ulawulo Oral beziyobisi uqale ne nedosi ye-200 mg (ngamanye amazwi, amacwecwe-2 kathathu ngemini, emva kwesidlo). Emva kokuba inani elichaziweyo legalelo unyango yehliswa ngesiqingatha. Ikhosi ye iipilisi unyango kufuneka kuhlala akukho ngaphezu kwenyanga.

Xa izifo kakhulu kunye nokoyika amalungu zangaphakathi amayeza yaphathwa njengezingxobo. Kukho 2 iindlela yezolawulo isiyobisi: efakwa kunye intraarterial. Inkqubo yokuqala eyenziwa a dropper. Ukulungiselela le njongo, 1 igutyana 250 ml isisombululo iswekile okanye sodium chloride. nesilinganiso uthe iphethwe kwisithuba iiyure ezi-2.

Njengoko yolawulo intraarterial, oko ibhalwa ne nedosi ye-0.1 g nganye 50 ml umxube sodium chloride.

imiphumela emibi

Phakathi nemiphumela emibi kakhulu ezixhaphakileyo zezi zilandelayo:

• isiyezi, ixhala, zokulala, ukuxhuzula, cinca-cinca, intloko ebuhlungu;
• cholecystitis exacerbation, transaminases isibindi ophakamileyo, uphuhliso cholestatic hepatitis;
• ukugabha, imvakalelo nenzaliseko esiswini, isicaphucaphu, urhudo, ukungabi namdla;
• izigxala, ukothuka anaphylactic, ukurhawuzelela, nokudumba angioneurotic, anozizi kwesikhumba;
• kukuvela arrhythmias, iintlungu intliziyo, ukunciphisa uxinzelelo lwegazi, iintlungu stenokardicheskie;
• thrombocytopenia, leukopenia;
• yokuhlala, ifiphale umbono;
• exacerbation yesifuba, bronchospasm, insufficiency sokuphefumla;
• ukopha of umyalezo ezahlukeneyo.

Drug "Pentoxifylline": analogue, ixabiso

Analogs zithathwa iziyobisi amachiza zilandelayo:

• dragees "Agapurin" (100 mg) kunye isisombululo ukuba isitofu kwi ampoules (100 mg);
• tablets "Pot", amacwecwe wawutyabeka (600 mg);
• dragees, amacwecwe kunye nesisombululo injectable "Trental".

Kufuneka kuqatshelwe ukuba "Trental" imele ichiza yokuqala. Wabelwe ukuba izigulane Encephalopathy lemvelaphi ezahlukeneyo.

Njengoko ngexabiso, ngoko zonke ezo amalungiselelo ngaba lwahlukile. Analogue "Trental" "Pentoxifylline" zingathengwa ngenxa engange 120 medicament yoqobo - kuba 520 engange "Agapurin" - engange-300, ngoxa "Pot" - 400 engange.

reviews

Reviews ngalo eli chiza ikakhulu positive. Amayeza iyasebenza izifo nemithambo amalungu kunye neenkqubo ezininzi. ukubuyekeza ezininzi nokusetyenziswa "Pentoxifylline" washiywa amadoda baphethwe lokutshabalalisa endarteritis kunye claudication uveza. Le medicament ngabo yindlela № 1, ekubeni esi sifo kuyaphela inkqubela.