Mastocytoma Canine (iseli lwemasti yamathumba ezinjeni). Yintoni na kwesi sifo ndinaso? Oonobangela, unyango, abantu abane

Mastocytoma - le neoplasm, echaphazela eluswini isilwanyana, oluthi luqokelelane yi iiseli imasti. Mastocytoma ezinjeni - kakhulu nezifo eziqhelekileyo yaye 22-25% yazo zonke izifo zolusu. Isikakhulu sifo sichaphazela umhlobo ezine-inemilenze ukuya kwiminyaka elithoba, kodwa abonakale besebancinane ngaphambili.

yamathumba iseli lwemasti izinja

Akukhathaliseki yeyiphi ngesondo izilwanyana: yamathumba bakwazi ukuphuhlisa njengenja le bitch. Noko ke, ngokutsho bezifo, ezinye iintlobo ezininzi ezithandwa izigulo kwaye basemngciphekweni. Ezi ziquka Labrador retrievers, manqindi, Bulldogs, terriers Boston, setters, iinkunzi umhadi, Sharpey abaphethwe esi sifo kwezinye indebe.

Mastocytoma ezinjeni - kwiseli mast ithumba kwesikhumba. Ukuba kukho amaqela ezininzi yezi nangezilonda, esi sifo kuthiwa mastocytosis. Yamathumba wabumba evela mastocytes waziqulunqa ngokutsha.

iiseli Mast okanye iiseli lwemasti - iiseli zamajoni omzimba abandakanyeka ekubunjweni okulungisekayo kwamajoni omzimba kwaye afumaneka kwizihlunu nokuqina. Bona ziqulathe granules ezithile eziquka lweeHedfowuni, histamine, interleukin kunye proteases cala, nto leyo evusa iindlela ukuziphendulela eyenzelwe ukukhusela umzimba ezenzeka ngaphandle kunye nezo ziphuma ngaphakathi.

Njani yaye kutheni esi sifo senzeka

iiseli Mast ibekwe ikakhulu ngaphantsi kwesikhumba omelene ezalathelwe nkovu kunye imithambo yegazi. Nangokuvela okuqhubekayo yeemeko ezimbi iiseli lwemasti ihlenga Iifom mastocytoma inja, oko kubangela ayiqondwa ngokupheleleyo.

Iingcali zikholelwa ukuba unobangela sifo wezakhi le oncogene into ephathelele ukusekwa egazini kunye nokukhula iiseli ngamanqatha. A ukulungisa le gene kungabangela uphuhliso somhlaza.

Indlela ukuba baziphathe ithumba, kuxhomekeke kwizinto ezimbini:

1. Kwiimpembelelo zasekuhlaleni kunye olucwangcisiweyo phezu izilwanyana kwezinto vasoactive wakhululwa iiseli imasti.
2. Ukukwazi metastases thumba ze uqale ukubetha iiseli yomhlaza nezibilini.

asabela Local e izinto vasoactive akhululwe inokuba nomahluko: nokudumba, izilonda, erythema kwindawo le neoplasm.

reactions Systemic ziquka isifo isilonda esiswini, perforation esiswini kunye neendonga isisu, apho kungenzeka peritonitis.

Amaninzi mastocytoma ezinjeni uvela ngokucwangcisekileyo, xa iiseli lwemasti athunyelwa amalungu amaninzi yangaphakathi: udakada, isibindi, lomongo wethambo kunye nezinye. Kulo mzekelo, esi sifo ikhula mastocytosis.

ngezigaba mastocytoma

Mastocytoma ezinokuba ndidi ezininzi:

1. oyedwa sodwa - luphawulwa ukukhula kade.
2. yamathumba manqapha, iindawo nkovu kuwenza.
3. ngamathumba ezininzi.
4. iseli leukemia imasti kunye mastocytosis.

Uphawu kweeseli useko lwemasti kukuba ukuba ungaqhubeka zombini kwangumqondiso kunye nazimpawu.

Ukwahlula amanqanaba amathathu lwemasti cell yamathumba ezinjeni:

1. In-degree yokuqala neoplasm uluhlu eluswini kwaye ingozi. Baya kuba mkhulu yaye kunzima ukuba ukusebenza, kodwa akukho bungozi ukunwenwa kwamanye amalungu kunye namalungu omzimba.
2. Xa Inqanaba lesibini nethumba eqalisiweyo nwebu ongama. Apha ndazilanda ezinye iimpawu yobubi, yaye ngoko ke andazi ukuba i modem ayisebenzi iiseli unyango.
3. Xa-degree lwesithathu ezindaweni ongama achaphazelekayo. Oku mastocytoma kakhulu ngumsindo ifuna indlela ekhethekileyo unyango.

imbonakalo mastocytoma

Mastocytoma ezinjeni zihlale njenge mshini, kuba oko ngeendlela ezininzi kwaye sixelise naziphi na izifo zolusu. Neoplasms ingabonakala ifana Iintsumpa eziqhelekileyo nendlela dermatitis ofumileyo, kwaye ibonisa isifo esiyingozi kunzima, yaye maxa wambi akunakwenzeka ngaphandle uviwo okhethekileyo.

symptomatology kwesifo

Xa isiqingatha esiseleni lwemasti ithumba ichaphazela isikhumba emzimbeni inja, kodwa kunokuba kwenzeke entloko, entanyeni nasebusweni. Maxa wambi esi sifo wabonakalaliswa emqaleni, amalungu okucola, okanye empumlo. Ngenxa yokuba mastocytoma kunzima ukubona, ngokufuthi bezilwanyana wabeka sifo lobuxoki kwaye amisele unyango engalunganga. Nayiphi ukukhula entsha kufuneka ifundwe ngenyameko.

Mastocytoma kaninzi kuthatha ifomu maqhuqhuva naphakathi ezibangela ukurhawuzelela ngayo. Inja iqalisa ukukamana imfundo yabo zibe bomvu ebushushwini babo. Kule ndawo ye Ithumba waphawula ilahleko iinwele. Xa touch ithumba isilwanyana ubonisa ixhala, ngenxa yokuba kakhulu buhlungu. Mastocytoma kwaye uguquguquka ngokukhawuleza, kwaye kade.

Indlela ukuhlola ithumba

obubonakala ezithile ezenzeka nangezilonda, kukho kancinane, kodwa kulula ukubona esebenzisa i biopsy. Ngokuthatha material isebenzisa inaliti entle, ngoko ke inja phantse na zintlungu. Izinto abamba zithunyelwa ilebhu isifundo ngokucokisekileyo.

Iiseli ezakha mastocytoma, ezinkulu ngeenxa zonke. Bathi ziqulathe izinto ezinokubangela ukugabha, izilonda esiswini, ukothuka kwaye ikhokelele ekufeni.

iiseli Mastotsitomnye babe umlinganiswa ukwazeka kakhulu. Nanamhlanje, akukho ndlela ingundoqo ukwahlula ithumba ukuba izakuqhubeka ngolona hlobo ukuba zenzeke, iyakhula kwaye ikhokelele ekufeni ngamathumba siyanyangeka.

Kwanele ukuba ukufumanisa zomhlaza eklinikhi "Biocontrol" ngokuchanekileyo. iklinikhi Veterinary Igxininisa izifo ezifana kunye nezinto eziyimfuneko.

Ukuze kumiselwe ALS esi sifo, kufuneka ukuchonga kakuhle isidanga-hlukeneyo yemfundo, nto leyo iya kubonisa ukuba ngaba iiseli umhlaza ezahlukileyo ebubonisayo, yaye yintoni na amathuba gula.

Ngokusekelwe koko diagnosis

Moshilongo olufanelekileyo wenziwe uthotho lweemvavanyo zonyango, apho unika umfanekiso oluneenkcukacha lokuqhubeka sifo. Umzekelo, iklinikhi lwezilwanyana "Biocontrol" Kashirka xa uphethwe:

• ukufunda idatha sifo, khangela qabane, uphando olunzulu;
• eziphilayo olupheleleyo wegazi;
• ultrasound esiswini ngenxa bhaqo okanye ngaphandle metastases;
• -X-reyi ye thoracic kwaye uqikelelo dorsoventral amabini;
• njengeminqweno biopsy ukwakhiwa kwiindawo nkovu, leyo abakhuselekanga kungcoliseko kuqala;
• ukufunda lwezonyango ezinomongo wethambo.

iklinikhi Veterinary "Biocontrol" Kashirka ligxininisa unyango izinja kunye ngumhlaza ngo-1965 kwaye usebenzisa zonke iindlela ezaziwayo zonyango.

ayini mastocytoma

Ekuchongeni izifo ezifana mastocytoma, unyango unikwa ngokusebenzisa enye yezi ndlela:

1. Surgery - ukususwa yamathumba. Le ndlela isebenza kuphela ukuba kunokwenzeka ukususa ithumba iseli lwemasti, yokufakwa kule 2-3 cm ephilile ibekwe phantsi uluhlu. Susa mastocytoma yenza ingqiqo kuphela kwi zigaba yokuqala neyesibini, kuba isifo isasazeke ngokukhawuleza kwizicwili angabamelwane. Ngaphambi kokuba ahlinzwe, inja unikwe unyango antihistamine ukuthintela ukothuka anaphylactic, kunye uxabane.
2. Indlela unyango radiation. Kuliwa njengoko unyango zaseprayimari nasesekondari. Isiphumo kuxhomekeke umahluko zeeseli neoplasms ixabiso. therapy Imitha isetyenziswa ukuba ithumba ayisuseki kunye neeseli mastocytoma banamanqanaba aphantsi umahluko. Njengenyathelo olongezelelweyo exposure unyango iyaboniswa phambi nasemva kokuba ukusebenza kwi ezikhoyo omkhulu kangaka.
3. Indlela nechemotherapy. Isetyenziswa phambi yobubi kunye metastases kwi kwiindawo nkovu yengingqi. Intsingiselo yale ndlela kukusetyenziswa ezithile neziyobisi ukuvimba uphuhliso iiseli kunye nezamkeli ezithile. Ubukho kwezi receptors bubonwa uhlalutyo immunohistochemical, ngokuhlola isakhiwo thumba.

Iziphumo zazo naziphi na iindlela zonyango zixhomekeke isifo kwaye inyathelo layo percolation. Ngenxa yoko, ukuphathwa isigaba sokuqala nesesibini esi sifo kunye olungephi ukuya kwiqondo ezilungileyo umahluko kweeseli ithumba emva unyango yesilwanyana aphile ngokomyinge ngaphezu kweminyaka emibini. Kumanqanaba yesithathu neyesine kunye differentsirovniya eliphantsi isidanga emva inja unyango bangabi ngaphezu kweenyanga ezintandathu.

Njengoko mastocytoma kwi inja uyiphendula ichemotherapy

Xa chemotherapy eqhelekileyo elabelwe "prednisolone" imo, idosi ebalwa ngokungqinelana ubunzima isilwanyana. Emva kweeveki ezimbini Umthamo ngetshekhi. Ke ukuba nemiphumo emihle ayivezi, oko yabelwe lo protocol ichemotherapy elandelayo entlantlu "cyclophosphamide", "Vinblastine" yaye "prednisolone".

"Prednisolone" Amaxesha amaninzi isetyenziswe mastocytoma. Izilwanyana kakuhle loo nto idluliselwa kunye nexesha ulawulo ungatsala iinyanga ezintandathu. Ukuba ngexesha unyango yamathumba ezintsha zabonwa, ichiza ukuze kurhoxiswa.

Phambi ichiza kunokwandisa ubunzima bomzimba, ukwandisa ukutya, unxaniwe, kusenokubakho izibhaxu ezosulelayo ulusu kunye dyspnea. Ngokuqhelekileyo, Nani linganisani ukungacoleki kokutya, izifo isilonda Peptic ne-pancreatitis. Ukuba iimpawu ezinjalo ukwenzeka, unikwe unyango edibanayo ukunciphisa iziphumo ebezingalindelekanga.

Ukuba Ithumba ibekwe kwiindawo engavumelekanga, okanye oko ayisuseki, ngoko isicelo ukuhlanganiswa ichemotherapy. It abangaphangeliyo ukukhula thumba kunye ukusasazeka kwayo wonke umzimba ixesha elide, esenokuba iiveki, iinyanga kunye neminyaka. Zalisa ukutshatyalaliswa iseli lwemasti Ithumba akunakwenzeka, kodwa ezinye izilwanyana banako ukuphila iminyaka embalwa ngakumbi ukufikelela iminyaka eziphilayo.

Landela-up emva unyango

Zonke izilwanyana ziphathwe yi mastocytoma, kufuneka babe phantsi kweliso lomgadi oncologists lwezilwanyana. Umzekelo, "Biocontrol", iklinikhi lwezilwanyana, eyenza kakhulu kwi unyango of Oncology, kwenkundla isigulane ngasinye.

Kwimeko ukubhaqwa kunye nonyango ngexesha ithumba nezolo kwandisa amathuba okuba ukwandiswa ubomi bayo. Ngokuqhelekileyo uhlolo inja yenziwa emva kwesithuba seeveki ezintandathu ukuya kwezisibhozo emva kokususa mastocytoma zonke iiveki ezintathu - kwimeko nechemotherapy. Ngamaxesha athile iingcali ndisiphumeze cingo nocazululo eziyimfuneko.

Yintoni na uqikelelo?

Nangona ukuba izifo ezifana mastocytoma inja, i-ALS kunzima ukukwenza, kodwa kukho ezinye iimpawu ukuba ukubonisa iimfuno ezintle kwesi sifo. On ukuziphatha mastocytoma ichaphazela ngokuhlelwa ibakala nethumba, kwakunye nobudala inja. Kuxhomekeka amaphononongo immunohistochemical ezibonakalisa inani iiseli ezingaqhelekanga kunye nokusebenza unyango.

Ngoko ke, aphezulu-grade mastocytoma isilwanyana ingaphila ixesha elide ngokwaneleyo ukuze Amanzi yokuphila abangaxhalabisiyo diferentsirovannoy ukusuka kwiminyaka yokuqala ukuya kweyesithathu, ngoxa ezisezantsi-grade - ukusuka kwiinyanga ezi-6 ukuya ku-12.

Iimeko eziphembelela ukuziphatha ithumba

1. Ubungakanani-hlukeneyo.
2. Iqonga apho ithumba ifunyenwe esandleni sakhe.
3. Indawo neoplasms. Iintelekelelo worst ozinikiweyo ngenxa yamathumba ibekwe emlonyeni phezu inwebu yangaphakathi.
4. ubukhulu ithumba. Le mastocytoma elikhulu, ithuba ukungamfaneli ayaphumelela.
5. Kubungakanani bophuhliso. amathuba recovery ukuba wancipha xa ukukhula ngokukhawuleza yamathumba nokutshatyalaliswa izicwili ezikufutshane.
6. Iimpawu inkqubo yokwetyisa bathi malunga nokungahoywa sifo.
7. Ubudala Iqela lezilwanyana. Okona yezilwanyana, anzima xesha ngayo.
8. Inja obona ngokwesondo. Ngokutsho izifundo, izinja kukunyamezela ichemotherapy unobubi ngaphezu nabasetyhini.
9. uhlobo isilwanyana. Kwezinye mastocytoma nga olufunyanwa usaqala, ezifana manqindi. Ngamanye isifo kubonakala kuphela kwimo yokungahoywa. Umzekelo okuphawuleka elibukhali.

amanyathelo othintelo

Ngelishwa, akukho ndlela eya kuthintela ukuyilwa yamathumba cell imasti. Isiphakamiso kuphela kubanini inja, ingakumbi kumaqela umngcipheko, i esweni lomgadi integuments umhlobo ezine-inemilenze, khangela kubukho amatywina ezahlukeneyo. Kwaye akukho ngozi iya kuvavanywa rhoqo kwiingcali.

Mastocytoma - yingxaki enkulu kunye nezintsonkothileyo, zombini ngokwemiqathango isifo kwaye afumane unyango. Ukugula ifuna isifundo qualitative. Yintoni a mastocytoma kule nja, ukuba ukusebenza okanye hayi, ukuze aphathe aze aphilise ukuba kunokwenzeka njani - imibuzo enjalo enyakazelayo entlokweni yam yonke mkhosi olungileyo. Konke kuxhomekeke kuxeshani ezi izifo, kwaye ukusuka iziphumo zophando lokuqala. Yaba neziphumo ezincumisayo ze ukunyanga umhlobo ezine-inemilenze wonke ithuba lokuphila elide ngokwaneleyo (kwimigangatho inja).