Ichiza "acyclovir-akos" (tablets). Imiyalelo zokusetyenziswa abantwana kunye nabantu abadala, ncomo

Koko nempilo prescribers "acyclovir-Agos"? Imiyalelo zokusetyenziswa kwezi tablets ithiwe thaca apha ngasezantsi. Kwakhona, uya kufunda kutheni usebenzisa esi sixhobo, ukuba ngaba uneziphumo ebezingalindelekanga kunye Izimo, iqukiwe kumafa yayo, yaye yintoni package iya lihlile.

Ubume, inkcazelo, ukupakishwa kweziyobisi

Ukuba ngawaphi amacandelo iqulathe "acyclovir-Agos" (tablets)? Imiyalelo Sebenzisa ithi icandelo ebonakalayo ichiza acyclovir. Kwakhona iquka kunye izithako ezongezelelweyo talc, nemagnesium stearate, namazambane istatshi.

"Acyclovir-Agos" - iipilisi (feedback nomonde ziza kuchazwa kamva) Valium emhlophe kunye Valium kunye kuyinkalo. Ekuthengisweni ichiza engena iiseli nentaba ukuthi ibekwe kwi ibhokisi. Kwakhona, eli yeza ikwafunyanwa kwi kwiindonga yeglasi emnyama.

Iimpawu amayeza ye ichiza

wenza "acyclovir-Agos" (tablets) njani? Imiyalelo Sebenzisa ithi ukuba arhente antiherpetic antiviral. Le ichiza a purine zokwenziwa analogu analogue. Uyakwazi ukuba kuthintelwe phindana wentsholongwane egazini we herpes simplex, cytomegalovirus, kanye igciwane Epstein-Barr kunye varicella zoster.

iimpawu imithi

Ngokutsho kweengcali, "i-acyclovir-Agos", izimvo zazo HIV ukuba kakhulu, oko kubonisa umsebenzi esihle iintsholongwane ezibangela herpes zoster, kunye irhashalala.

Emva kokufumana le medicament kwi iiseli ezosulelwe phosphorylation iqala. Acyclovir iguqulelwa monophosphate acyclovir. Phantsi yempembelelo yokugqibela guanylate cyclase iguqulelwa kulo diphosphate nto leyo, aguqulwa ukuya triphosphate.

Isiphumo ukukhetha beziyobisi kwi ntsholongwane, ngokunjalo yetyhefu esezantsi kwi eziphilayo ngenxa yokuba isithako yayo esebenzayo asiyonto zeendawana ngenxa kinase enzyme thymidine. Kule nkalo, akukho awunatyhefu kwiiseli mammalian.

Emva ukuguqulwa ku acyclovir acyclovir triphosphate ngayo abangaphangeliyo ukuba Yindibanisela viral DNA iindlela 3:

• ithatha indawo deoxyguanosine triphosphate;
• ihlanganiswe chain DNA, uze uphele zobude yayo;
• nefuthe ngxelo imbi kwi DNA ye herpes simplex njalo njalo.

Ngenxa yokuba sesichengeni enjalo eyeka intsholongwane ukuba ukulingisa.

ngendlela acyclovir kwakhona ngenxa nokwanda yalo iiseli abasele bosulelwe yintsholongwane. Herpes kweziyobisi ithintela ukuyilwa izilonda ezintsha, kwaye ikhuthaza ukuphiliswa amanxeba, kunciphisa iintlungu kwaye isiphumo immunostimulating.

Pharmacokinetic iparameters amacwecwe antiherpetic

Apho ukufakwa lwenzeka "acyclovir-Agos 'iziyobisi? Imiyalelo yokusebenzisa lithi emva ulawulo yomlomo oko kukhutshwa amancinci etsalwe emathunjini. Kule fom ngokoxinzelelo (yedosi-kuxhomekeke), nto leyo kwanele ukuba unyango olusebenzayo izifo wentsholongwane egazini.

Ukutya phantse nafuthe kukufakwa into esebenzayo. Ngokwandayo amathamo le bioavailability ye nokuncipha iziyobisi.

Le xi liphezulu ichiza emva khona ngaphakathi kwi-mali ka-200 mg 5 amaxesha ngosuku yi-0.75 g / ml, kwaye ubuncinane - 0,45 g / ml. La manani zithi iiyure ezimbini kamva.

Plasma protein esisebenza enebana 10-35%. Utyhutyha le umqobo igazi-ingqondo, ngokunjalo phantse kuzo zonke izicwili kunye namaziko (nemiphunga, ingqondo, ulwelo lacrimal, zezintso, emathunjini, isibindi, izihlunu, uburharha zolwelo, ubisi lwebele, amadlozi, udakada, fluid, wesibeleko, ngasese kunye ngenwebu yangaphakathi lobufazi, kwakunye imixholo vesicles herpetic).

Drug yokucolwa esibindini. Oku kwenza metabolite 9-ebizwa karboksimetoksimetilguaninom.

medicament ibonakala kwizintso (62-91% ye-dose) kunye ngokusebenzisa lokugaya. Kwakhona umkhondo imali beziyobisi azimisele kwaye okhutshwa sisigulane.

Xa ekufumaneni ichiza ngaphakathi kwayo-isiqingatha ngobomi (abadala) yi - Iiyure ezi-3.4, yaye abantwana (iminyaka 1-18) - Iiyure ezi-2.4. Ngenxa yoko, kukhuselekile ukuqaphela ukuba izinga kukhuthaza ichiza ehla kunye nobudala.

Iimpawu medicament

Xa kulawula "acyclovir-Agos"? Ukusetyenziswa kweli chiza iboniswe lokhuseleko kunye nonyango losulelo ezibangelwa ziintsholongwane varicella zoster kunye Herpes simplex (iintlobo-1 no-2). Ngoko ke, eli chiza ngempumelelo ubaphatha:

• herpes simplex isikhumba kunye uxakaxa imifinya (zaseprayimari yomhla nezolo);
• herpes zoster;
• herpes angasese (zaseprayimari yomhla nezolo);
• herpes zoster;
• varicella (Ngosuku lokuqala emva livela yabangxamayo).

Kufuneka kuqatshelwe ukuba umsebenzi ichiza emiselweyo ukuba izigulane immunodeficiency kakhulu (umzekelo, abantu abosuleleke-HIV, ukufakela ngexesha uthatha amayeza immunosuppressive).

Izimo

Kwezinye iimeko, aluvumelekanga ukusebenzisa "acyclovir-Agos" (tablets)? Khokela amanqaku le Izimo zilandelayo:

• abantwana yobudala (iminyaka emithathu);
• hypersensitivity ukuya into esebenzayo, kwaye kunxulumene valacyclovir.

Ngononophelo kakhulu, eli chiza emiselweyo ngexesha lokukhulelwa, ukusilela kwezintso emzimbeni, kwakunye ngexesha lokuncancisa.

Drug "acyclovir-Agos": indlela yokwenza abadala?

Ezi tablets kufuneka kuthathwe ngomlomo, ngaphandle kokujonga izidlo kunye iglasi yamanzi mmandla.

Abadala ukuba unyango bale ntsholongwane, i-herpes simplex kwi inwebu yangaphakathi kunye nesikhumba emiselweyo 200 mg beziyobisi izihlandlo ezihlanu ngemini. Thatha iyeza kufuneka ube zonke iiyure ezine (ngaphandle ukulala).

Ngokuqhelekileyo, ubude unyango kule ukulungiselela iintsuku ezintlanu. Kodwa ukuba kukho imfuneko, ukuze zihlaziywe (ngokulandela iingcebiso kagqirha).

Xa unyango abantu immunodeficiency idosi enye amayeza lanyuka ukuya 400 mg, yaye ngalo lonke ixesha lokuqhubeka kwekhosi - up iintsuku ezilishumi nangaphezulu.

izigulane abadala herpes angasese Kucetyiswa ukuba ukuthatha amachiza 200 mg amaxesha ezinezifundo ezintlanu (rhoqo emva kweeyure ezine) iintsuku ezili-10 (ukuba unyango kufuneka ungadluliselwa). Unyango kufuneka ziqale ngokukhawuleza kangangoko kunokwenzeka emva kokuvela Iimpawu zokuqala mkhuhlane. Ukuba kukho likakade, ichiza kumiselwe sele kwixesha prodromal.

Ukuthintela ukuphinda lweNTSHOLONGWANE ukuba zibangelwa yi-herpes simplex virus, amayeza emiselweyo 200 mg izihlandlo ezine ngosuku (qho kwiiyure ezintandathu). Abantu abane okukwazi eqhelekileyo Ungasebenzisa ichiza isixa 400 mg kabini ngosuku (qho kwiiyure ezili-12). Xa wavakalisa immunodeficiency idosi ihlala enye, nangona kunjalo, esi rhoqo inyuswe ukuya izihlandlo ezihlanu ngosuku.

herpes nezolo zangasese (oko ubuncinane izihlandlo ezintandathu ngonyaka) kufuneka ithobele kwirejimeni ilandelayo: 200 mg kahlanu ngemini kangangeentsuku ezintlanu. Ukuba iziqephu ziphindwa amaxesha ngaphezulu ezintandathu ngonyaka, isigulane emiselweyo 400 mg beziyobisi kabini ngemini iinyanga ezili-12. Ubude prophylaxis kudla emiselwe lonke ixesha xa kukho ingozi yosulelo.

Xa unyango lwe-herpes zoster okanye zoster nomonde elawulwa 800 mg beziyobisi kahlanu ngosuku (rhoqo emva kweeyure ezine) iintsuku 7-10.

Ithamo iphezulu olunye ichiza 800 mg.

Abantu abathatha amathamo aphezulu ichiza kufuneka kufumana isixa esikhulu ulwelo.

"Acyclovir-Agos" (tablets): lokufundisa abantwana

Neentsana, ogama yobudala sele ifikelele iminyaka emithathu, ichiza kufuneka ilawulwe kuphela bezifo abanamava. Ngokuqhelekileyo, esithathwa kuzo iyafana esithathwa abadala.

Ukunyanga abantwana irhashalala kweminyaka engama-emithandathu ukunika 800 mg beziyobisi kane ngemini, waza abaneminyaka umntwana iminyaka 3-6 - 400 mg kane ngemini. Kuba amagqirha ongaka ngqo ngakumbi usebenzisa le ndlela ilandelayo: 20 mg ngalinye kg umzimba weight baby. Thabatha medicament ngaphezulu kwe 800 mg ezine ngemini akuvumelekanga.

Ubude unyango kubaguli abaselula iintsuku ezintlanu.

Xa abantu abane umsebenzi kidney kakuhle kufuna uhlengahlengiso zedosi, ngelixa kufumana rhoqo. Kuxhomekeke kuhlobo yosulelo nezinto ezilixabiso yokususwa creatinine.

nemiphumela emibi emva kokungenisa iipilisi

Medicament "acyclovir-Agos" kunqabile kakhulu ibanga iziphumo ebezingalindelekanga. Kodwa, ngokwemiyalelo, sekunjalo kufuneka nendawo ukuba.

1. Isicaphucaphu, ukwanda izikhombisi yibilirubin, urhudo, iintlungu esiswini, ukugabha, ukwanda ingathityazwa enzyme zesibindi.
2. ukusilela Acute kwezintso, ophezulu amanqanaba serum creatinine egazini kunye urea.
3. Leukopenia, igazi, thrombocytopenia.
4. Intloko ebuhlungu, ukuba nemibono, iingxaki zezivamvo, ingathityazwa, ukudideka, isiyezi, paresthesia, ukozela, angabikho zingqondweni, yombono.
5. Irhashalala, dyspnoea, photosensitivity, angioedema, irhashalala, ifiva, pruritus, lymphadenopathy, anaphylaxis, ukuphazamiseka, ukungaboni, nokudumba yoluvo, myalgia.
6. Ukudinwa, alopecia.

Kufuneka kuqatshelwe ukuba abantu abafumana antiretroviral, kwabaza amayeza "acyclovir-Agos" akuthethi ukuba kukho ukwanda kakhulu neziphumo ezinetyhefu.

iingcebiso ezithile malunga nokusetyenziswa kwemali antiherpetic

Into ekufuneka uyazi phambi kokuba uthathe i "acyclovir-Agos" (tablets)? Umyalelo ithi unyango elide okanye okuphindwayo abantu kuncitshiswa ubume omzimba kungakhokelela ukuyilwa Ngeentlobo intsholongwane ukuba unovelwano wesenzo.

izifundo ukhuseleko lwezonyango ngokusetyenziswa eli chiza ngexesha lokukhulelwa alubanga. Kulo mba, ukusetyenziswa kweziyobisi "acyclovir-Agos" iboniswa kuphela xa ezinokuba luncedo unina kakhulu obungaphezu ingozi olungekazalwa.

Xa unyango iidosi eziphezulu ngomlomo isigulane kufuneka usele ngokwaneleyo amanzi.

Ngethuba lokuncancisa amayeza wabelwa kuphela kwiimeko ezigabadeleyo, ikhosi emfutshane. Oku kungenxa yokuba beziyobisi imali encinane ibe ubisi lwebele.

Medicament "acyclovir-Agos" oko kuthintela usasazeko herpes ezidluliselwa ngeentlobano zesini. Kulo mba, ngexesha lonyango, isigulane kufuneka basenokuziphepha iintlobano zesini.

Izimvo lezigulana amayeza

Ngoku uyazi ukuba amisele njani yaye kutheni ichiza "acyclovir-Agos". imiyalelo yokusebenzisa le ndlela sikhokelo iye ichazwe ngokwenkcukacha ngasentla.

Ngokutsho impendulo uninzi lwezigulane ingxelo amayeza ngempumelelo esizibonakalisa izilonda ezibandayo. Ukuba uthathe ipilisi ngoko nangoko emva uzingela Iimpawu zokuqala herpes, ukuchacha isigulane iya kuba kakhulu ngokukhawuleza.

Kufuneka kuqatshelwe ukuba i "acyclovir-Agos" ngempumelelo ubaphatha ngamaxolo kunye irhashalala.

Ukongeza kuthomalaliso, ichiza isoloko isetyenziswa njengenyathelo lothintelo. ndlela yakhe sokunene inceda ukunciphisa inani likakade ukuya ubuncinane.

Ixabiso beziyobisi

Kufuneka kwakhona wathi ukongeza ichiza kahle eliphezulu "acyclovir-Agos" izigulane bonwabile kunye nendleko zabo iphantsi kakhulu. Thenga iipilisi 20 antiherpetic ukulungiselela 30-40 engange Russian. Imali elikhankanyiweyo kwanele ukuba ikhosi unyango.

Ke kaloku, lowo kufuneka ngexabiso eliphantsi kunye analogue beziyobisi.