I-potassium chloride: uphawu kunye nokusetyenziswa kwezolimo nakwiyeza

I-potassium ion (K +) yinkqutyana ebalulekileyo yesiqhelo se-intracellular. Kwi-cytoplasm yeseli, malunga ne-90% ye-potassium iyagxininiswa. Ukuphefumula kwe-potassium kubangelwa ikakhulu emathunjini amancinci. Ubunzima bawo obubalulekileyo ukusuka emathunjini angena egazini, kwaye emva kokungena kwizicubu. Ukuqhawulwa kweli qumrhu kumzimba ngenxa yeentso. Kwi-urine, i-potassium iqulethwe kwifom yeesalts (i-sulfate, i-phosphate) kunye ne-organic (uric) acids. Indima ephambili yee-K + ion emzimbeni igcina ukukhutshulwa kweeseli, ngokuyinhloko kwezihlunu. I-potassium i-chloride kwi-concentrations ephantsi iyanciphisa ubukhulu kunye nobukhulu beentliziyo zecala. I-myocardium ithatha ingqalelo kwi-i-K + ions ukunyuka ngokunciphisa ukuqhutyelwa nokukhutshwa. Ukugqithiswa kwesi sidakamizwa kunokubangela nokuba kubanjwe intliziyo. Ukusilela kweli nqanaba kwi-plasma yegazi kwandisa umngcipheko we-arrhythmias. Oku kuya kwenzeka xa kusetyenziswa iqondo elincinci le-carlyac glycosides (digitalis). Ngokuthatha inxaxheba yeon i-potassium, ezifumaneka kwi-erythrocyte, i-oxygen kunye ne-carbon dioxide zihanjiswa yi-hemoglobin. Ukuchithwa kwamanyathelo kuthatha inxaxheba kwiinkqubo zokuqhubela nokuhanjiswa kweempembelelo zamathambo kwizitho ezingenakulungiswa. Ukuba i-potassium i-chloride ingeniswa emzimbeni, ngoko umgangatho we-acetylcholine kunye nokuxhaswa kwengxenye yenceba ye-nervous system yanda kakhulu. Ukulawulwa kwezidakamizwa kweziyobisi kuvuselela i-adrenaline excretion yi-adrenal glands. I-potassium i-chloride, njengoko kunjalo, kunye nezinye izaluthi zale nxalenye ibonakalisa umphumo wesisu.

Kufuneka kuthathelwe ukuba le nxalenye enkulu ibandakanyeka ekugcineni isilinganisi se-acid-base emzimbeni. Uthatha inxaxheba kwimimiselo yoxinzelelo lwe-osmotic, ukwakheka kunye ne-hydrolysis ye-phosphate compounds enezityebi zamandla (ATP, AMP, ADP, ukudala i-phosphate, njl.), Kwiinkqubo ze-phosphorylation. Umgaqo we-potassium metabolism emzimbeni ngenxa ye-aldosterone. Xa ukukhutshwa kwe-aldosterone kuyancipha, i-excretion ye-potassium iyancipha ngamacandelo ahlukeneyo yeetluli ezigqithisiweyo zeentso, ngoko ukukhululwa komchamo kunciphisa, kunye nokugxininiswa kwi-serum yegazi, i-intercellular fluid kunye neeseli, ngokuchaseneyo, iyanda.

I-potassium chloride: ukusebenzisa kwiyeza

  Isibonakaliso sokusetyenziswa kwesi sidakamizwa ngu-hypokalemia, i-arrhythmias yeentlobo ezahlukeneyo, ukuxiliswa kunye nokulungiswa kwe-digitalis, kunye ne-hypokalemic ye-myoplegia ye-paroxysmal. Ukuze kuncitshiswe imiphumo emibi ye-hydrochlorothiazide, i-potassium i-chloride ifakwe kwezinye iziyobisi ezichanekileyo. I-Hypokalemia ingabangela ukuphazamiseka ekusebenzeni kwenkqubo yeentlanzi, iintliziyo zeentliziyo, inkqubo yokujikeleza kunye neentso. Ngamanye amaxesha i-hypokalemia iphelela ngokukhubazeka komzimba kunye ne-coma.

I-potassium chloride imisela ngaphakathi ngaphakathi, kwaye i-intravenously. Ixesha eliqhelekileyo ulawulo lwe-parenteral lusetyenziswa kwezo meko xa kuphepheka ukuphelisa ngokukhawuleza iziganeko zentsholongwane. Ukwenza oku, sebenzisa isisombululo se-4 yeepilisi kwi-40% i-glucose. I-potassium chloride kufuneka isetyenziswe ngokuqaphela okukhulu. Uphawu lokuqala lwekliniki lokuxiliswa yi-paresthesia. Ukuxiliswa kunye nokulawulwa kwangaphakathi kungabonakalisa njengentlungu, ukuhlanza kunye nehudo.

I-potassium i-chloride iyachithwa ngokuchonga abo baphulaphulo kwimisebenzi yezintso. Kule meko, i-K + ions iqokelele egazini, leyo ingakhokelela ekuphuhlisweni kotywala.

Potassium Chloride: Isicelo kwizoLimo

Le ityuwa yinkomati ephezulu ye potassium. I-potassium chloride isetyenziselwa ukutshala ingqolowa, kunye nezinye izityalo ezingenakuchukumiseka kwiziphumo ezinobungozi be-chlorine. Izityalo ezixhambileyo kwizenzo ze-klorine ziyifleksi, iitapile, ucuba, utamatisi, izityalo zokuvumba, kunye neziqhamo zase-citrus. Ngenxa yoko, ukuchumisa ezi zityalo, i-potassium chloride ayikhuthazwa.