"I-Nolpaz": imiyalelo yokusetyenziswa kwamacwecwe xa kwenzeka isilonda sesisu nesisu esiswini

"I-Nolpaz" isichengisi se-hypoacid ehambelana neziyobisi zokulwa ne-antiulcer, kwiqela elivimbela ipompo yeproton. Isilwanyana sisetyenziselwa ukuthintela nokuphatha unyango lwephepha lokutya. Kukho izifaniso zeziyobisi zeNolpaz, ezifana nePanum, iZepantola, Controller, Pepazol, Sunpras, kunye nePantaz. Bonke babenomxholo osebenzayo "kwi-pantoprazole", ekuxhomekeke kwintsholongwane kunye nexesha elide ekukhutshweni kwe-secretion ye-hydrochloric acid.

Ukubunjwa kunye nefom yokulungiselela "uNolpaz"

Umyalelo uyazisa, ukuba kwi-tablet ye-1 ye-gastroresistant imithi "uNolpaz 20" iqukethe i-20 mg ye-pantaprazole. Kwiphebhulethi "Nolpaz 40" - 40 mg yezinto ezisetyenziswayo. Kwakhona, kukho izinto ezincedisayo ekulungiseleleni, kuquka ne-sorbitol.

Isenzo se-Pharmacological yesilwanyana "uNolpaz"

Umyalelo ubhekisela ekulungiselelweni kweziyobisi zokulwa ne-antiulcer - i-inhibitors yamapompu yeproton (H + K + ATPase). Isilwanyana sinakho ukunyusa ukunqandwa kwe-secretion ye-hydrochloric acid. Isiza sisebenzisana noHelicobacter pylori kwaye sikwazi ukuphucula umonakalo we-Helicobacter wezinye iziyobisi.

Emva kokuthatha ithebhulethi ye-Nolpaz, impembelelo yokwelapha ibonakalisa ngokukhawuleza kwaye iyaqhubeka yonke imihla. Nge- injection engena - intravenous ye- 80 mg yesilwayo, isenzo sokulwa ne-antitisecretory sifinyelela kwinqanaba elingaphakathi kweyure kwaye liqhubeka ixesha eli-24, elibangela ukunciphisa ngokukhawuleza iimpawu kunye nokuphilisa izilonda kwi -duodenum. Xa ugxinyiweyo, ukugqiba ukugqiba kwenzeka ngokukhawuleza. Kwinqinci elincinci, iyeza likwazi ukungena kwi-BBB, kunye nemfihlelo iyafumaneka kubisi lwebele. I-metabolism yesilwayo ivela esibindi. Ngendlela yemetabolites idityanisiwe, ikakhulukazi kumchamo, ngexabiso elincinci lingafumaneka kwi-stool. Ayikho ikhono lokunyusa.

Iimpawu zesilwanyana "uNolpaz"

Umyalelo unikezela ukusetyenziswa kweziyobisi xa:

- gastroesophageal reflux pathology of degree;

- ukuthintela kunye unyango lwezigulane ezine-reflux esophagitis kunaliphi na isigaba;

- unyango lwabantu abaneesisu esiswini okanye isisu se-intestinal peptic, kunye ne-Zollinger-Ellison syndrome kunye nezinye iimeko ezihambisane noxinzelelo;

- ukuthintela izilonda kwizigulane ezithe zafumana izidakamizwa ezichasayo ezingapheliyo .

Isilwayo "i-Nolpaz" sinokumiselwa kwipilisi enzima kunye neziyobisi ezinokubulala i-antimicrobial for the destruction of Helicobacter pylori.

Ukungqinelana kwisiza "Nolpaz"

Umyalelo awucebisi ukusetyenziswa kweziyobisi ukuxhaswa kwe-hypersensitivity, i-hepatitis kunye ne-cirrhosis yesibindi, kunye ne- hepatic insufficiency .

Imiqathango yokusetyenziswa kweziyobisi "uNolpaz"

- ngokuphulwa kwesibindi,

- ebuntwaneni,

- ngexesha lokukhulelwa, i-lactation.

Iziphumo eziPhakathi

Kwimimandla yesondlo sesisu isabonakaliswa:

- urhudo;

Umlomo owomileyo,

- ukwandisa ukutya,

- isicasiso,

- ukubetha,

- ukuhlanza,

- Flatulence,

Intlungu esiswini,

- ukuqothulwa,

- ukwandiswa komsebenzi we-transaminases,

- I-gastrointestinal carcinoma.

Kwiinkqubo zeentlanzi kunye nezitho zengqondo:

- intloko;

- asthenia, isiyezi, ukulala, ukulala;

- ukwethuka, ukudandatheka, ukuthuthumela, i-paresthesia;

- photophobia, ukungaboni kakuhle, ingxolo ezindlebeni.

Kwi-genitourinary system:

- hematuria,

- edema,

- ukungabi namandla.

Ekhumbeni:

- alopecia,

- Acne,

- dfoatitis exfoliative,

- Ukuphendulwa kwemizwa ngesimo sokuqhafaza, ukuvuthwa, ukuvumba, i-angioedema.

Enye ifomu:

- Hyperglycemia, myalgia;

- umkhuhlane, i-eosinophilia, i-hyperlipoproteinemia, i-hypercholesterolemia.

Ukusebenzisana namanye amachiza

Ngokusetyenziswa kwangaphandle kwesilwanyana "i-Nolpaz" kunye namanye amayeza, ukugqithiswa kwe-ketoconazole kunye nezinye iziyobisi ezixhomekeke kwi-pH-dependence absorption.

Izindlela zesicelo

Iipilisi "I-Nolpaz" zithathwa ngomlomo, 40 mg - 1 ukwamukelwa ngosuku, ekuseni. Iqondo eliphezulu leyeza liphindwe kabini.

Xa unyango lwezilonda zesilonda esibangelwa yi-Helicobacter pylori, izicwangciso zonyango zisetyenziswa ngokubambisana ne-clarithromycin kunye ne-metronidazole.

Ukugqithisa

Akukho zichazi zeempawu. Xa kunokudluleka kwamanzi, kunconywa ukuba kuqhutywe isondlo kunye nonyango olumqondiso. I-Dialysis kule meko ibhekwa ingasebenzi.

Imiyalelo ekhethekileyo

Ngaphambi kokonyango, kuyimfuneko ukukhuphela ukufumaneka kwezifo ezimbi zesifo kunye nesisu. Akukhuthazwa ukuba kuqeshwe izigulane nge-dyspepsia ye-etiology engeyiyo. Izigulane ezisebekhulile kunye nomsebenzi onokukhubazeka awukhuthazwa ukuba unike umthamo ongaphezu kwama-40 mg / ngosuku. Ukuba kukho ukungafihleki okukhulu kwe-hepatic, i-regimen yesilinganiso kufuneka iguqulwe, ilawule izinga le-enzyme ye-hepatic.