"Diza" (iipilisi anti-engavumelani): imiyalelo ukusetyenziswa, analogs, ncomo

Indlela yokusebenzisa ichiza "Disa"? Imiyalelo yokusebenzisa esi sixhobo iza thaca ngezantsi. Kwakhona uya kufunda ukuba udweliso zifakiwe kwi ifomu iziyobisi wathi kuyo iyafumaneka, ukuba kunokwenzeka ukumisela ukuba abantwana kunye nabasetyhini abakhulelweyo.

Ekwakhiweni, imilo, inkcazo medicament

Ziziphi amacandelo iquka iziyobisi "Disa"? iipilisi Anti-nokwaliwa, ukuqeqesha liyinxalenye ibhokisi luhlaza, lenticular kunye setyhula kwimilo, ngokunjalo nemiqadi «LT» kwicala elinye. Eyona nto elikhutheleyo ichiza desloratadine. Kwakhona iquka izinto ezongezelelweyo mannitol microcrystalline kwincindi, pregelatinized umbona starch nemagnesium stearate kunye talc.

Ke ukutyabeka umboniso iipilisi, ziquka blue Opadry, macrogol kunye indigo idayi.

Kufuneka kwakhona uqaphele ukuba ichiza ingqalelo ekuveliseni ngendlela isiraphu. isithako yalo nezenzo desloratadine.

Pharmacology

Njani ichiza "Disa" (iipilisi anti-engavumelani)? IMimiselo olubekwe kule ndawo, wathi ukuba kukho antihistamine elide-esebenza. Yeyona blocker histamine peripheral H1-receptor.

Eyona nto elikhutheleyo medicament kukho metabolite ephambili akhutheleyo loratadine. It abangaphangeliyo lo uxabane nawo, ukukhupha cytokines proinflammatory kunye chemokines. Kwakhona, lo msebenzi osemqoka kunciphisa ukwenziwa anions superoxide, chemotaxis kunye adhesion of eosinophils.

kuzichanaba ichiza inceda ukuthintela ukunwenwa nokuququzelelwa negazi lakho. ukulungiselela kujongwa uye protivoekssudativnoe kunye antipruritic iimpawu, kuthintela ziba imisipha agudileyo, nokudumba izicwili kwaye kucutha permeability ngcanjana.

Tablets "zokuchela", ixabiso apho zizakuboniswa ngezantsi, lungenasiphumo kwi-CNS, kodwa ibe okulalisa (ngamanye amazwi, ingabangeli ukozela) kwaye alunasiphumo kwi lengqondo asabela (xa efumana idosi kucetyiswa). Ukongeza, beziyobisi umbuzo alibandakanyi QT lekhefu phezu electrocardiogram.

Isiphumo therapeutic beziyobisi kuqala kwisithuba seyure emva kokungenisa, kwaye sihlala imini yonke.

Pharmacokinetics

Yintoni iziyobisi pharmacokinetic uye "Disa" (iipilisi anti-engavumelani)? Guide uthi emva ukuthatha into esebenzayo ichiza ngayo ako kakuhle ukusuka phecana zesisu. Xa plasma kokuba ugqibe kangangesiqingatha seyure, kwaye ubuninzi eyavela ekufikelelwe kuso emva malunga neeyure ezintathu.

Unxibelelwano yokulungiselela plasma iproteni yi 85-87% kunye nokupheliswa nesiqingatha-ubomi - 28 kwiiyure. desloratadine idubule na imveliso ngokusebenzisa emathunjini (ngaphantsi kwe-7%) kunye nomchamo (ngaphantsi kwe-2%).

Ubungqina obubonakalayo buxela

Ukususela nezidlo kweziyobisi phezu kobuso inceda kakuhle kakhulu. Isetyenziswa kuphela ukuba kube lula, kodwa ukuze kupheliswe mpawu zilandelayo:

• ezindlwini zazo (irhashalala okanye ukurhawuzelela);
• nokuthimliswa komzimba (impumlo esihambisayo, ukuthimla, ukurhawuzelela ye inkalakahla, ingxinano ngeempumlo, ububomvu kunye ngamehlo, impumlo sirhawuzele, amehlo alilayo).

Izimo

Ukususela komzimba ngexesha lokukhulelwa iziyobisi "Disa" kufuneka zisetyenziswe. Kwakhona, oko akayibonisanga ngexesha lokuncancisa kunye nabantwana abangaphantsi kweminyaka eli-12 ubudala (ukhuseleko kunye nokusebenza akukasekwa). Musa ukusebenzisa oku medicament yaye ubuthathaka ephakamileyo isigulane ezikhoyo okanye naziphi na izithako eyongezelelweyo medicament.

Ngononophelo kakhulu "Disa" ipilisi omiselwe insufficiency kakhulu sezintso.

Drug "Disa" (iipilisi anti-engavumelani): Imiyalelo

Amisele iipilisi kufuneka ube yincutshe elimxinwa kuphela. Nokwaliwa (urticaria, pruritus, irhashalala, njl) abantwana ukusuka kwiminyaka eli-12 kunye nabantu abadala ngokufanayo basuswe. Ngokutsho imiyalelo, cwecwe kufuneka kuthathwe ngomlomo, kungakhathaliseki ukuba ukutya ukutya. Le umthamo ichiza emiselwe ngugqirha kwaye kaninzi-5 mg kanye ngemini (ngamanye 1 ipilisi nganye ngosuku).

ukusabela ezingalunganga

Umzimba abantwana abangaphezulu kweminyaka eli-12 ukulungiselela 'Disa "imele ukwenziwa ngononophelo obukhulu. Oku kungenxa yokuba eli chiza kungabangela inani elikhulu yeziphumo ebezingalindelekanga.

Kaninzi, izigulane kufuneka ukusabela ezingalunganga ezifana ukudinwa, intloko ebuhlungu engapheliyo, kwaye kome emlonyeni.

Ngexesha kokuma nabo sele zichongiwe kwaye nezinye iziphumo ebezingalindelekanga. Sinikela ngoku:

• Ukususela luvo bangafumana nobuthongo, lengqondo ukungahlaliseki, isiyezi, kunye ugwayi.
• Ngomhla inxalenye wokugaya kukho intlungu esiswini, urhudo, isicaphucaphu, ukuqunjelwa, kunye nokugabha.
• Ukususela iphecana biliary kunye wesibindi kwenzeka iziganeko ezifana njengoko ukwanda uyondelelwano lwee- yibilirubin, enzyme zesibindi kunyuswa aze hepatitis.
• Ezesifuba izigulane nemithambo ndinexhala tachycardia kunye iyangongoza.
• Ngomhla yinxalenye yenkqubo bone kwemisipha i waphawula myalgia.

Kufuneka kuqatshelwe ukuba ngexesha uthatha ingqalelo beziyobisi izigulane zinokuba ukuphazamiseka engqondweni njengoko nemibono kunye negazi ezifana ukurhawuzelela, anaphylaxis, irhashalala, urticaria kunye angioedema.

Iimpawu libanda

Umzimba abantwana phezu iminyaka eli-12 kunye nabantu abadala iziyobisi "Disa" kufuneka zithathwe ngeedosi ekucetyiswa ngugqirha.

Emva kokufumana ichiza ngeedosi eziphezulu (umzekelo, amaxesha 9, ngokucacileyo ilingana no 45 mg) akazange naziphi na iimpawu ngokwezonyango ebalulekileyo ekukhuliseni. Kodwa ukuze aphuhlise ukozela.

Njengoko unyango kufuneka ukuba iphume esiswini kwaye wenze namalahle. Kufuneka kuqatshelwe ukuba desloratadine na isiphumo ngu olugqitha esikhumbeni.

Ukuhambelana namanye amachiza

Intsebenziswano "Disa" iziyobisi kunye nezinye iziyobisi ziye zachongwa (kuquka "Erythromycin" yaye "ketoconazole"). Kufuneka kwakhona wathi desloratadine akuthethi ukwandisa isiphumo ethanol kwi-CNS.

izincomo ezithile

Nokwaliwa (urticaria, pruritus, irhashalala, njl) ukwenzela abantu ongaboniyo kakhulu sezintso kufuneka aphathwe ngokuqaphela okukhulu.

Ngokutsho izifundo, ichiza "Disa" alunasiphumo kwi izithuthi zolawulo nomonde. Kodwa ke kufuneka kusoloko kukhunjulwa eyayingafane ukuphuhlisa ukozela abanye abantu. Kulo mzekelo, kufuneka uthathe unonophelo olulodwa ngoxa uqhuba naxa usebenza iindlela ezintsonkothileyo.

Ixabiso kunye analogue beziyobisi

Ngokungafaniyo nezinye izinto antiallergic, ixabiso le "zokuchela" isiyobisi nga phezulu kakhulu. Thenga le medicament kunokuba kuba engange 200-350 (10 nezidanga 30, ngokulandelelanayo).

Ngokumalunga oothixo ingqalelo ichiza, lukhona eninzi. Nazi ke: "Lordestin", "Blogir-3", "Aerius" "desloratadine", "Eliza," "desloratadine-Teva", "Ezlor" "desloratadine Canon", "Nalorius" "desloratadine-Farmaplant".

Izimvo amayeza nokwaliwa

Drug "Disa" - engabizi nokwaliwa kweziyobisi, nto leyo washiya kakhulu zombini reviews ezimbi nezilungileyo. izigulane ezininzi ingxelo ukuba amayeza kakuhle ukumelana msebenzi. Ngokukhawuleza nangempumelelo kususa onke iimpawu i uxabane nawo, ukuphucula ngokubonakalayo imeko yesigulane.

Abantu abathatha i "zokuchela" iipilisi zibonisa ukuba ukusetyenziswa kwazo Kulula kakhulu. Ngokungafaniyo nezinye iziyobisi, ingqalelo ngokwaneleyo ukuze bathathe amayeza kanye ngosuku, kwaye ungakwazi bayakhohlwa komzimba.

Le medicament, kukho ncomo negative. izigulane abaninzi abakwazi ukuthatha loo nto, njengoko kubonakala kwangoko negazi lakho. izigulane ezinjalo amagqirha ukumisela amayeza ezikhuselekileyo.