Togu "iDiflucan" - lithetha "i-fluconazole"

Togu "iDiflucan" - lithetha "fluconazole" - i-arhente nokubola ukuba nefuthe kakhulu ethile. Ichiza ekwaziyo uvimba umsebenzi kwezinye enzyme, zinqanda inguqu lanosterol ukuya ergosterol. Ukongeza, ichiza kwandisa permeability of inwebu yeseli, ukuthintela ukukotshwa kunye nokukhula kwamagciwane. Ichiza kakuhle lwezifo ezinzwaneni amathuba nomsindo nomngundo uhlobo Candida, kubandakanywa iindidi omzimba nolahlo ngokubanzi of candidiasis emhlabeni. Ngamayeza ngomlomo absorbability elungileyo. Ngomlinganiselo ukufunxeka alichatshazelwa ekudleni. Le bioavailability beziyobisi yi malunga ne-90%. isiqulatho esiphezulu egazini ufikelela unyango kwimizuzu 30-90. Ichiza isasazwa kakuhle ancedisana ulwelo ukugqobhoza kungena ubisi. Kufuneka ke ukuba ixabiso ichiza "fluconazole" umyalelo sezingeni ngaphantsi ngexabiso 'iDiflucan "(kwixesha elidlulileyo kuya kufuneka ukuba uhlawule ukusuka engange amane anamanci ukuya anamanci asibhozo).

ubungqina

Medicine "fluconazole" (analogu "iDiflucan") liza yanikelwa cryptococcal meningitis, cryptococcosis kunye nezinye kwendawo usuleleko cryptococcal kwizigulane kunye impendulo eqhelekileyo omzimba kunye neentlobo ezahlukeneyo omzimba. Ngu ubungqina candidiasis ziquka uhlobo ngokubanzi, candidiasis zasasazwa, candidemia, kunye nezinye iintlobo zosulelo invasive ebangelwa ngundo Candida. Iyeza kuyanconywa nokuthintela usulelo ezinzwaneni kwizigulane nangezilonda abuhlungu lomlinganiswa. arhente esiwabelwe iinyawo mycosis, nasemiphakathweni, esifubeni.

umthamo abakwisigaba

Togu "iDiflucan" - lithetha "fluconazole" - emiselweyo ukuba izigulane kunye kwiminyaka elishumi elinesihlanu xa enobunzima mkhulu kuno-50 kg. Xa izifo cryptococcal of eyendawo ezahlukeneyo ngosuku lokuqala ne nedosi ye-400 mg. Kamva, isixa medicament lancitshiswa 200 mg ngosuku. Ubude unyango kwezi ezimbi ixhomekeke ukusebenza yonyango, nto ingqinwa izifundo mycological. Ukusetyenziswa kwe-cryptococcal meningitis kufuneka kuthabatha iiveki ezintandathu ukuya kwezisibhozo. Xa ziyithumele candidiasis, candidemia, kunye nezinye iintlobo usulelo Candida invasive ngosuku lokuqala imali ichiza - 400 mg, idosi liye lancitshiswa mg 200. Kwimeko ngempumelelo zaneleyo zonyango idosi inyuswe umva ukuya 400 mg. Ubude unyango kuxhomekeke ngempumelelo indlela.

effect side

Togu "iDiflucan" - ichiza "fluconazole" - kungabangela nesiyezi, iintlungu intloko, isisu, iintlungu esiswini, imnyama, isicaphucaphu. Ngenxa yokuba unyango inokuphuhlisa thrombocytopenia, negazi ezifana ekweneni ubuso, epidermal necrolysis ityhefu, isikhumba ukurhawuzelela. Amacwecwe Analogs kunokubangela uphazamiseko kwesibindi, izintso, hypokalemia, hypertriglyceridemia.

Izimo

Musa ukumisela ichiza phambi kweminyaka yobudala engama-4, xa kwimeko wayengabunyamezeli amabakala alo. Contraindicated ukusetyenziswa kudityaniswe medicament "Terfenadine", "Astemizole" kunye nezinye igalelo kungoluka QT-lokuphumla. Isilumkiso ngexesha unyango kunye bonisa ukuthambekela ezimbi ezahlukeneyo (ukuba electrolyte ukungalingani, isifo sentliziyo zendalo, njl njl).