Isiza "Trileptal": ukuphononongwa, imiyalelo yokusetyenziswa

Enye ye- anticonbulsants esebenzayo kwiminyaka yamuva iye yaba yi-Trileptal. Ukuphononongwa kuye kukuphawula ukunyamezela okubhetele ngakumbi xa kuqhathaniswa ne-"Finlepsin" eyayisasazeka. Oku kubangelwa zizodwa zezenzo zeso sixhobo - luzinzisa umsebenzi wee-neurons, ukuthintela ukunyusa kwabo kunye nokuqhelanisa ukuhamba kweentsholongwane zemisipha kwimisipha. Esi silwanyana senziwa eSwitzerland usebenzisa ubuchule bwanamhlanje. Ngoko ke, kusebenza ngakumbi kunezinye iindlela. Iingenelo zalo ziquka into yokuba kulungele ukunyamezela, kwaye kuthathe ixesha elide kunokwenzeka. Uninzi lwezigulane lubona ukukhulula okupheleleyo kokuthintela isisu emva komnyaka weyeza kunye neT Trileptal.

Iimpawu zokulungiselela

"I-Trileptal" yilisiza esisisiseko esisebenzayo esisisigxina se-oxcarbazepine. Iveliswa ngendlela yamacwecwe okanye ukumiswa, okubizwa nangokuthi isiraphu ngenxa yokunambitha kwayo. Kule fomu kungcono ukunika "i-Trileptal" kubantwana. Impendulo evela kwizigulane kunye noogqirha ibonisa ukuba kulula ukulandela umlinganiselo ochanekileyo xa isetyenziswe. Emva koko, enye ipilisi iqulethe phakathi kwe-300 no-600 mg ye-oxcarbazepine, eyona dose kubantu abadala. Ukongezelela, ukumiswa kunomdla okothambileyo kunye nephunga elimnandi.

Ukusetyenziswa kweziyobisi

Kwimeko enye kuphela - ngokuhluthwa - kucebisa ukuba uthathe imiyalelo ye-Trileptal yokusetyenziswa. Ukuphononongwa kwamanqaku okubaluleka kwakhe okuphezulu xa kuthelekiswa nezinye iziyobisi zokulwa ne-antiepileptic. Inkqubo yesenzo senkunkuma isekelwe ekukhutshweni kweziteshi ze-sodium. Oku kukhokelela ekumeni kweempembelelo kunye nokuzinza kwee-neurons. Ukongezelela, i-oxcarbazepine iholele ekusebenzeni okuncinci kwee-calcium. Isici sale nkunkuma kukuba ayichaphazeli i-neurons yengqondo.

Ubuncinci obuninzi bokusetyenziswa kwezinto eziphambili I-Trileptal kwi-plasma yegazi ibonwa emva kweeyure ezingama-4-6. Kwaye ngeli xesha lidityaniswe emzimbeni, ikakhulukazi ngeentso. Ngoko ke, kubaluleke kakhulu ukuthabatha amayeza rhoqo ukufezekisa impembelelo.

Iimpawu zokusetyenziswa

Kwi-strophyy, abadala kunye nabantwana bavame ukushiywa i-Trileptal. Izimvo zoogqirha zibeka uphawu lokusebenza kwayo ephezulu kunye nokunyamezela kakuhle xa kuthelekiswa nezinye iindlela ezifanayo. Isilwanyana sisetyenziselwa i-monotherapy kunye namanye amayeza. Yinike yona nayiphi na indlela yokuhluthwa kunye nokuhlaselwa kweJackson. Ukuphumelela "i-Trileptal" kunye nokuhlaselwa kwesifo se-epidemic, kunye ne-tonic-clonic.

Ukongezelela ekuthintela nasekunciphiseni ukutshatyalaliswa kwexinano, esinye isibonakaliso sokusetyenziswa kweT Tripleptal yi-neuralgia. Iingxelo zoogqirha zibonisa ukuba kule meko iphumelele ngakumbi kunamachiza asetyenziswa ngaphambili. Ukongezelela, isilwanyana simisa isimo sengqondo somguli. Iphelisa ukuguquka kwemizwelo kwaye inqande ukuphuhliswa kwengcinezelo.

Trileptal: imiyalelo yokusetyenziswa

Iingcamango zogqirha kwiimpawu zamachiza imfuno yesazi echanekileyo. Kucetyiswa ukuba ungathathi ngaphezu kwe-10 mg kilogram yesisindo ngosuku. Kubantu abadala, eli liphakathi kwamaphilisi amabili. Yingakho abantwana befuna ukunika isiraphu ye "Trileptal". Umyalelo uncoma ukuba ugubungele ibhotile ngaphambi kokusetyenziswa kwaye msinya ukulinganisa inani elifunekayo leziyobisi kunye nesirinji ekhethekileyo. Kubantwana abancinci, kucetyiswa ukuba kungabi ukwandisa umthamo. Unokuthatha ukumiswa kwangoko kwisirinji okanye uhlambe ngamanzi. I-vial evulekile ingagcinwa kungekho ngaphezu kweenyanga ezi-2.

Thatha "Trileptal" 2 amaxesha ngosuku. Ingadliwa ngaphandle kokutya, kodwa kuyinto enqwenelekayo imihla ngemihla ngexesha elifanayo, ngokukhawuleza. Imilinganiselo yokuqala yabantu abadala ngokuqhelekileyo isiqingatha sebhebhile kabini ngosuku. Kwixesha elizayo kuyavunyelwa ukuba ukwandise kancane umthamo ukuya kwiipilisi 1-2 ngokufumana. Kodwa kukho unyango oluyinkimbinkimbi kuyimfuneko ukulungisa umlinganiselo wesinye isiyobisi.

Ubani le chiza lichazwe

Eli phephelo limiselwe abantwana ukusuka kwinyanga e-1. Kodwa kufike kwi-3 kuphela kuphela ukumiselwa kwe "Trileptal". Amanqaku okufundiswa kakuhle ukubekezeleka kunye nokusebenza kakuhle kwiimeko xa ezinye iziyobisi zingenakunceda. Kodwa akubona zonke izigulane ezinokuhluthwa zingathatha i-Trileptal. Ukuchasene nokunyanga nokukhulelwa. Kuye kwabonakaliswa ukuba i-oxcarbazepine ibangela ukungasebenzi kakubi kwiintsana kule meko.

Ilumkiso kufuneka lithathwe ukuze lithathe "i-Trileptal" kubantu abanokukhubazeka kakhulu kwesibindi kunye nomsebenzi wezintso. Musa ukumisela iilisi kwakhona kwizigulane ezinokunganyameli kwale nto. Ngako oko, xa ukuphendulwa kwe-allergenic kwenzeka, kufuneka uyeke ukuthatha i-Trileptal. Iziganeko ezikhoyo kule meko kufuneka zincede ukhethe ugqirha.

Sebenzisa kubantwana

Kubaluleke kakhulu ukunika "i-Trileptal" kubantwana ngokuchanekileyo. Ukuphononongwa kubonisa ukunyamezela okuhle kwe-ejenti kunye nesilinganiso esifanelekileyo. Kucetyiswa ukuba uqale nge-8 mg yesigidi nganye ngeekhilogram ubunzima bomntwana ngosuku. Kancinci, umlinganiselo we "Trileptal" unokunyuka, ufike ku-30 mg nge kilogram. Kodwa xa isetyenziselwa kunye nezinye izidakamizwa ze-antiepileptic le dose kucetyiswa ukuba kufikelelwe ngaphaya kweeveki ezimbini.

Kuvela ukuba abantwana banikwe kwisilinganiselo esiphezulu kunomntu omdala we-Trileptal. Izimvo zabazali zibonisa ukuba akubona wonke umntu oqonda ukuba kutheni le nto yenzeka. Enyanisweni, ukuxinwa kwezinto ezisebenzayo zonyango ngokunyuka kwandisa ngokukhula. Ngoko ke, ukufezekisa impembelelo efunwayo, abantwana badinga umthamo owandisiweyo. Oku kungenxa yeziganeko ezibonakalayo zesibindi kunye nokusebenza kwezintso kubantwana.

Izixhobo zokusetyenziswa kweziyobisi kumdala

Ukulungiswa kwe dose ye "Trileptal" kunokufuneka kwiigulane ezingaphezulu kweminyaka engama-65. Kule minyaka ubudala, umsebenzi wezintso uvame ukukhubazeka. Ngoko ke, ngokumkela "i-Trileptal", ukwehla okubukhali kwesodium egazini kunokwenzeka. Ezi zi gulane zifuna ukunyamekela ngonyango oluqinileyo kunye nokuvavanywa rhoqo kwamazinga e-sodium. Ngako oko, unyango oluhlangeneyo lusetshenziselwa ukuba luphephe ukugqithisa kakhulu kunye nemiphumo emibi. Kodwa ngokusisiseko "i-Trileptal" ixhomekeke kakuhle kwaye, xa isetyenziswe kakuhle, inceda kakhulu imeko yesigulane kunanoma yiphi iminyaka. Ukongezelela ekubanjweni kokuthintela, kunokunciphisa intloko ephuma kwiintsholongwane zamathambo, ukukhusela i-blood clots, ukuphucula ukusebenza, ukunciphisa uxinzelelo kunye nokwandisa ukusebenza kwengqondo.

"Trileptal" ekukhulelweni

I-Oxcarbazepine iyangena ngokukhawuleza kwisithintelo se-placental, ngoko iphikisana nabafazi abathwele umntwana. Isiyobisi singabangela ukukhubazeka okungaphantsi komntwana, kaninzi kungahambelani nobomi. Mhlawumbi uphuhliso lomlomo wempisi, imilebe yomlomo. Oku kungabangelwa kuphela kwimiphumo emibi ye-oxcarbazepine. "I-Trileptal" ibangela ukwehla kwinqanaba le-folic acid, esele yincinci kakhulu ngexesha lokukhulelwa-oku kungabangela ukukhubazeka.

Ngoko ke, ibhinqa kufuneka ilumkiso malunga nemiphumo enokuthi ithathe izidakamizwa ngaphambi kokuba ukhulelwe kwaye ngexesha lokuzala komntwana. Kwaye kubalulekile kunyango lwe "Trileptal" ukusetyenziswa ukukhusela ukukhulelwa, kungekhona iipilisi zokulawula ukuzala, ukuphumelela okunciphise kakhulu phantsi kwefuthe layo, nezinye iindlela.

Imiphumo emibi yeziyobisi

Ukongeza kwindlela yokuphendula okufunekayo, apho i-10% yezigulane zifumana ezinye iimiphumo ezimbi zonyango. Yintoni ebangela igalelo le "Trileptal"? Iingxelo zokuphonononga ukuba ngokuqhelekileyo kukho imiphumo engathandekiyo:

• Ukutywabalala, umbono ombini, i-nystagmus, umbono otyumkileyo;
• Ubuthathaka, ukukhathala, ukulala;
• Intloko;
• Isisindo, ukuhlanza, ubuhlungu besisu, umsebenzi wokukhubazeka;
• Ukunganakwa, ukudandatheka, ukukhathazeka kwemizwa;
• Ukulibala, ukunciphisa ingqwalaselo;
• I-Rash, ukubonakala kweempuphu elukhumbeni, ukulahleka kweenwele.

Ukusebenzisana kwezidakamizwa

Esi sidakamizwa esinzulu singathatyathwa ngokungqongqo ngokwemiyalelo emva kokuqeshwa kogqirha. Kubaluleke kakhulu ukujonga ngokuchanekileyo umlinganiselo kwaye ungaphazamisi unyango. Kuyafana nokusetyenziswa kwamanye amayeza kwizigulane ezithatha i-Trileptal. Umyalelo ubeka ingqalelo enkulu kule nto, ekubeni ukuvunyelwa ngokubambisana kunye neziyobisi ezithile, i-oxcarbazepine ingatshintsha okanye isenzo sayo.

• Akukhuthazwa ukusebenzisa i-oral contraceptives kwizigulane ezithatha i-Trileptal. Uphononongo lubonisa ukuba le nkunkuma inciphisa ukuphumelela kwemali esekelwe kwi-ethinyl estradiol okanye i-levonorgestrel. Ngoko ke, ngexesha lokonyango kuyacetyiswa ukuba usebenzise ezinye iindlela zokukhulelwa.
• Ngolawulo olufanayo lwama-"Trileptal" kunye neziyobisi ezisekelwe kwi-phenobarbital, phenytoin okanye i-carbamazepine, ukugaya kwayo kuyancipha. Ngoko ke, kulo mzekelo, kufuneka ulungelelanise umyinge weyeza ukwenzela ukuba ukuphumelela kwayo kungaphumeleli.
• Ezi zonyango ezifana ne "Felodipine" okanye "i-Verapramil", kunye nezofana nazo, ziyakongeza ngakumbi ukugaya "i-Trileptal".
• Eli liyeza lomeleza kakhulu umonakalo wokunxiliswa kotywala kunye nokulungiselela utywala.

Ukugqithisa ngokutsha kweziyobisi

Kwimilinganiselo yokunyangwa okucetywayo, i-Trileptal ithathwa njengekhuselekile. Iingxelo zokuphonononga ukuba iziganeko zokugqithisa kakhulu ziyinto engabonakaliyo. Kule nto kufuneka uphuze amacwecwe amaninzi ngokukhawuleza. Kodwa ukugqithisa ngokubanzi izidakamizwa zokulwa ne-antiepileptic kunokwenzeka ngonyango oluyinkimbinkimbi kunye nokwamkela "i-Trileptal" kwinqanaba elingaphambili. Yintoni eyenzekayo kwimeko?

• Ibhalansi yamanzi-electrolyte, ebonakaliswa ngokungabikho kwamanxuwa e-sodium.
• Iqumrhu lokubona liyabandezeleka: kukho umbono ombini emehlweni, ukungabonakali, i-nystagmus.
• Umsebenzi wendlela yokugaya iphazamiseka, isigulane sivakalelwa ngumsindo, kunokuhlamba.
• Ngokuqhelekileyo kukho ubuthathaka, ukukhathala, ukuphazamiseka kokulala, utywala, uxinzelelo lwegazi oluphantsi.
• Ukudideka okunokwenzeka, ukuphazanyiswa kokuhambelana nokuhamba, ukubonakala kobugwenxa nokucaphuka.
• Kwiimeko ezinzima kakhulu, kukho ukungasebenzi kwempilo yokuphefumula, ukuxinwa, ukulahlekelwa yintliziyo kunye ne-coma.

Ukuba ukugqithisa kweziyobisi kwenzeka, kuyimfuneko ukuhlamba isisu. I-Adsorbents, umzekelo i-carbon dial, inikwe kwakhona. Ukuthintela oku, kuyimfuneko ukufundisisa umyalelo ngaphambi kokufaka i-Trileptal.

Iimpawu ze-Analog zesi sixhobo

Ayikho imithi eninzi ephethe into efanayo esebenzayo njengeTrileptal. Enyanisweni, kuphela "i-Oxcarbazepine".

Ngoko ke, ezinye izidakamizwa zokulwa ne-antiepileptic zibhekwa njengezifana neziyobisi "Trileptal":

• Finlepsin.
• Tegretol.
• "Gabapentin".
• ICarbamazepine.
• "Phenytoin."
• Valproat.

Uphononongo malunga neziyobisi

"Trileptal" ithathwa njengenye ye-anticonvulsants best. Izigulane ezinokuhluthwa kunzima kakhulu ukukhetha unyango olululo. Kwaye ngokuqhelekileyo iqala ngezinye iziyobisi. Kwimeko apho kungekho nto inceda, yiya ku "Trileptal." Iingxelo zoogqirha malunga nale mpiliso zithandekile. Baqaphela ukuphumelela okuphezulu kunye nokunyamezela kakuhle kweziyobisi. Nguye kuphela olungileyo kwiinkampu eziqhelekileyo kunye nokulahlekelwa kwengqondo. Yingakho bayisebenzisa ngokuqhelekileyo.

Ukongezelela, ezininzi izigulane ziyabona ukuba emva kokuba utshintsho kwi "Trileptal" luqala ukuziva luba ngcono. Xa kuthelekiswa nezinye izidakamizwa zokulwa ne-antiepileptic, kusebenza ngakumbi kwaye kubekezeleleke ngakumbi, kubangele imiphumo embalwa. Abantu bayabhala ukuba ekugqibeleni baye baba nekhanda kunye nokutshatyalaliswa kwelanga. Kwaye kunye nemiphumo emibi yechiza idla ngokugqithiswa ngokulala. Ukongeza, ezininzi izigulane ziphawula iindleko eziphezulu - malunga nesiqingatha samawaka ngamaphilisi ama-600 mg.

Omnye ummandla wokusetyenziswa ngokuphumelelayo kweziyobisi i-Trileptal yi-nerve trigeminal. Iingxelo malunga nokunyangwa kwe-neuralgia ziyabonakala ukuba ngokuqhelekileyo uyakwazi ukujongana ngokukhawuleza nentlungu. Kanye kunye nezinye iimpawu zesi sifo.

Kananjalo impumelelo isetyenziswa kubantwana abancinci "Trileptal". Ukuvakalisa kwabazali kaninzi kuqulethe inkcazo yokuba umntwana waqala ukuziva njani emva kokuqala kokonyango. Isilwanyana sinceda ukujamelana nokuhlaselwa ebusuku kwaye kulungelelanise isimo sengqondo. Nangona unyango lwangexesha elide kaninzi alubangela into ebaluleke ngaphezu kokulala.