Ichiza "Bekonaze": imfundiso, analogs kunye nohlolo

ziyabagulisa bamphazamise abantu abaninzi. Ukuze ukulahla izinto ezinjalo, oogqirha bacebisa ukusetyenziswa ezizodwa amachiza-kukwalisa, leyo kakhulu ngcono imeko yomguli kunye ishenxisa iimpawu ezingemnandi.

Kweli nqaku, siza kukuxelela malunga amayeza afana ngayo njenge "Bekonaze". ukusetyenziswa kwale ngendlela sikhokelo wengingqi nabo baya thaca apha ngasezantsi.

ifomu Release, ukwakheka, ukupakishwa

Ukulungiselela "Bekonaze" imfundiso leyo ifakwe kwi ibhokisi yekhadibhodi, enziwe into emilise isitshizi zolwelo isicelo ngeempumlo. Ilungu esebenzayo zesixhobo kuphuma beclomethasone dipropionate.

Intengiso iziyobisi zabonelelwa iibhotile kunye kwisixhobo okhethekileyo.

Pharmacology kwemali bendawo

Yintoni spray "Bekonaze", analogue kuzo zidweliswe ngezantsi? Le medicament ke glucocorticoid uhlobo intranasal mlonyeni leyo anazo anti-nokudumba, iipropati anti-ezithintela ukosuleleka kunye anti-komzimba.

Iinkcukacha malunga neempawu ichiza

isenzo Antiallergic beziyobisi ethathelwa ingqalelo ngenxa ukukwazi layo ukuze kuthintelwe receptor susceptibility nezinto zebhayoloji esebenzayo (histamine, prostaglandins) kunye nokushukunyiswa mechanical. Ngamanye amazwi, le isixhobo iba nefuthe ngqo kwi hyperresponsiveness lwabo non-ngqo.

Ukulungiswa ikhuthaza inhibition of weseli lwemasti degranulation, kunye nokususa onke kubonakaliswa asebenzayo yokukrala nature komzimba. Kwakhona ulibuyele ingqiqo ivumba. Yiyo le phawu eyenza amayeza "Bekonaze" (zokutshiza) ngezinye iindlela nxamnye komzimba.

arhente Izincomo uphucula izithuthi mucociliary kwaye alunasiphumo kwi neutrophils. Kulo mba, ichiza akusenzi omzimba kusuleleko amagciwane.

iipropati Anti-yokukrala "Bekonaze" ucacisa ifuthe layo phezu iiseli ngu receptors umdla athi abenoxanduva noshicilelo a zofuzo DNA ekujoliswe olawula Yindibanisela iimolekyuli protein inxaxheba kwiinkqubo arhabaxa.

Ngokutsho iingcali, iziyobisi esebenzayo uyakwazi zinqanda uqhelwaniso njini-nitric oxide, ukusebenza apho has a imiphumo iqapheleka pro-arhabaxa. Kwakhona abangaphangeliyo ukuba Yindibanisela cytokines pro-ukudumba ukuba bawaphikise inkqubo arhabaxa.

Kufuneka kwakhona uqaphele ukuba emva kokufaka isitshizi iyabhlokwa imveliso IgE kunye nokusekwa leukotrienes kwi inwebu yangaphakathi. Isiphumo medicament ngxelo imbi kwi umsebenzi zemfuza olawula kuyondelelaniswe enqanda kunye nezinye iimolekyuli protein, aqukiweyo kwinkqubo komzimba. Ngenxa yale isiphumo liyancipha inyama nokudumba kunye nokuhla secretion kwamadlala kule ingaphakathi.

Pharmacokinetics beziyobisi

ingaba ichiza ako, "Bekonaze"? Guide ingxelo ukuba ichiza kakhulu bafakwa ngokukhawuleza kungena isifo ngeempumlo. Malunga ne-5% of idosi esetyenzisiweyo ubengena negazi. Xa olu ukulungiselela biotransformed ngokupheleleyo sicatshulwa lokuqala esibindini.

bioavailability ephantsi kakhulu ichiza kunciphisa amathuba neziphumo ayinqweneleki phantsi ukusetyenziswa elide ukuya ubuncinane.

Ichiza sibophelela ukuba albumin 80-90%. Bawo-ubomi iiyure ezili-16. Medicament kuphele izintso, kunye endleni.

ubungqina

Yintoni injongo emiselweyo amachaphaza ngeempumlo "Bekonaze"? Ngokutsho iingcali, ichiza kusetyenziswa kwiinkqubo ukudumba imvelaphi noninfectious ezithi zenzeke em- ngeempumlo. Kwakhona isetyenziselwa nezolo polyposis ngeempumlo nokuthimliswa komzimba (ngamaxesha athile okanye unyaka-ngeenxa).

Izimo

Xa kufuneka usebenzise isitshizi "Bekonaze"? Izimvo oogqirha ingxelo ukuba oku kuthetha kukho iqela elikhulu Izimo. Akuyi Kucetyiswa ukuba basebenzise xa ukunganyamezelani beclomethasone, yaye kwiimeko ezifana:

• glaucoma, iposi engabalulekanga, inkqubo ngezifo sezintso;
• amoebiasis, herpes kwamehlo;
• isifo sephepha yemiphunga, kutshanje wasiwa nongcungcutheko utyando empumlweni;
• izifo systemic amagciwane okanye imvelaphi ziibhakteriya, hypothyroidism, izilonda ekudibaneni ngeempumlo;
• lokuncancisa, ukukhulelwa.

Drug "Bekonaze": mazwi

amayeza kubhekwe ukuba usetyenziswe intranasal kuphela. Kwi qela lobudala ezingabantwana kwiminyaka emi-6 kunye abadala ichiza Kucetyiswa ukuba basebenzise kwi idosi enye kwisiqingatha ngasinye lweHo- ngeempumlo. Ukusebenzisa instillation kufuneka kube kathathu okanye kane ngemini. Ukuba usebenzisa idosi kabini beziyobisi, oko lesitofu kabini ngemini.

Njengoko ibonisa yokusebenza, umphumo therapeutic saphawula emva kokuba isicelo wesipreyi ngeentsuku 5-7.

imiphumela emibi

Drug "Bekonaze", ixabiso yayo zidweliswe ngezantsi, kukhuselekile ngokupheleleyo abantwana abadala, nkqu kunye nokusetyenziswa ixesha elide. asabela ngayo systemic ezingalunganga izinto ezincinane.

Kwiimeko ezinqabe kakhulu, ichiza kunokubangela ngayo zasekuhlaleni ezingafunekiyo ezifana uthimla, evuthayo kwaye kome na isifo ngeempumlo, kwakunye ukopha kunye nosuleleko nezolo herpes. Ukongeza, kwiimeko ezinqabileyo, kukho perforation le zekhala ngeempumlo.

Phambi hypersensitivity kwi isigulane ngazo negazi ezifana urticaria kunye irhashalala.

Spray "Bekonaze": nabalingani kunye neendleko

Ukuba kuyimfuneko, ichiza "Bekonaze" kungenziwa indawo ngokusebenzisa ezifana "Agistam", "Ekvazolin", "Otrivin" "Marimer", "Kamfomen", "Physiomer".

Thenga ichiza "Bekonaze" ngokohlobo ngokutshizwa akuyi kuba nzima, ekubeni kuthengiswa phantse zonke nakwiikhemisti ngaphandle kwencwadi kagqirha. ixabiso layo uyahluka 800-950 engange.

Izimvo medicament

Baqinisekiswa malunga kuqulunqo langoku ukuba isicelo mlonyeni ziyabethabethana kakhulu. Umntu uthi yeyokuba isebenza kakhulu ukumelana umsebenzi kwaye kususa onke iimpawu nokuthimliswa komzimba, kwakunye ukudumba em- ngeempumlo of imvelaphi non-esosulelayo.

Noko ke, kukho udidi abantu ingxelo ukuba eli chiza akalutho ngokupheleleyo. Ngaphezu koko, kukho inani elikhulu lezigulane ezi kakhulu neentloni iindleko ichiza. Nangona iingcali zithi ixabiso layo ngokupheleleyo olungaguquguqukiyo.

Ingongoma kuphela ezintle kwesi sixhobo, apho bathi unguYe zonke izigulane kukuba kunqabile kakhulu ibanga iziphumo ebezingalindelekanga.