Drug "Bidop": ezibonisa ukusetyenziswa, analogs kunye nohlolo

uxinzelelo lwegazi oluphezulu kuphela kuzisa ukungaphatheki ebalulekileyo kwisigulana, kodwa esisongela ubomi bakho. Bunjani ubume bayo, abantu abaninzi babhenela kumayeza womthonyama. Noko ke, iingcali qaphela ukuba ukwanda eliphantsi uxinzelelo lwegazi ekhaya kulula kakhulu asezantsi ephakamileyo. Ngoko ke, bacebisa ukusetyenziswa kweziyobisi, eyenzelwe ngokukodwa ukulungiselela le njongo.

Enye amayeza kakhulu zithandwa nolusebenzayo lwegazi sisiyobisi njenge "Bidop". Iimpawu zibonisa ukuba ukusetyenziswa, analogs kunye nohlaziyo umsebenzisi la malungiselelo kuya kuxoxwa kamva. Uza kufunda kwakhona malunga nendlela yokusebenzisa kakuhle eli amayeza ukuba unazo naziphi na iziphumo ebezingalindelekanga kunye Izimo.

Inkcazelo, ifomu ukukhululwa, zokubopha nokwakhiwa kwamachiza

Drug "Bidop", analogue lwazo ethengiswa wonke Pharmacy, ifike ngohlobo amacwecwe ukukhanya amdaka iimbalasane tyheli inshorensi ifilimu. Bona aba ngeenxa, imilo biconvex with "B1" zokumakisha kweyona notshi kunye nenombolo "5" ( "10") ngaphantsi.

Le esisebenza ngayo esi sixhobo wenza bisoprolol hemifumarate. Njengoko yezigqeba abangabancedani, ngoko sebenzisa nabo monohydrate lactose, nemagnesium stearate, microcrystalline kwincindi, crospovidone kunye yellow PB sombala grade 22812 (13% yellow intsimbi oxide ne-87% lactose monohydrate).

Thenga iipilisi "Bidop", ukusetyenziswa apho kunyanzelekile ukuba abantu uxinzelelo oluphezulu lwegazi, ukuba kunokwenzeka namadyungudyungu kunye iipakethe ikhadibhodi ngokulandelelana.

Pharmacodynamic iparameters imithi

Yintoni na ichiza "Bidop"? Ubungqina obubonakalayo buxela ukuba kusetyenziswe isixhobo ngenxa amanyathelo yayo imithi. Le ichiza a β1-adrenergic blocker uyakhetha. It has akukho iziphumo sympathomimetic, kwaye lungenasiphumo ndizayo ozinzileyo.

Ingqalelo amayeza ekwaziyo yandisa umsebenzi renin, ukunciphisa imfuno ioksijini engabalulekanga nokunciphisa contractility yayo.

"Bidop" - ichiza leyo eye iipropati antianginal, antiarrhythmic kunye umfutho. Abathintela ezenza β1-adrenergic engabalulekanga (ngeedosi ezincinane), lunciphisa zothutho intracellular of ion calcium kwehlisa Yindibanisela emkhosini ATP (zichatshazelwa catecholamines) na isenzo chronotropic elibi, BATM, dromo- kunye inotropic, kwaye kwakhona ukucola Uhanjiso kunye excitability.

Xa edlula ukulungiselelwa idosi enyangayo ubonisa β2-adrenoceptor ekuvimbeni isiphumo.

Ekuqaleni unyango (ngemihla yokuqala), ukumelana neuropathy yeendonga nemithambo zinokukhuliswa. Emva kweentsuku 3, iba likufutshane neloqobo, kodwa yehla kakhulu emva unyango ixesha elide.

Iimpawu ichiza

Zeziphi iimpawu ezendeleyo medicament "Bidop"? Isenzo amayeza beziyobisi ngenxa nokubunjwa kwayo.

Isiphumo iqinile beziyobisi lu dityanisiwe ukuncipha imveliso kwentliziyo, ukukhuthazwa onovelwano neuropathy-uhlobo iindonga semithambo, kwakunye buthathaka umsebenzi kwenkqubo renin-angiotensin, impembelelo luvo kunye nokunciphisa ingxelo, nto leyo eza ukuphendula kuxinzelelo.

Ukuba lwegazi kuphuhlisa isiphumo kwezonyango beziyobisi iintsuku ezintlanu. isenzo sakhe ukuzithemba kufuneka kweenyanga ezimbini kamva.

Isiphumo antianginal okubangelwe yile amayeza? lencazelo "Bidop" isichazela ukuba isenzo esinjalo ebangela ukwehla engabalulekanga ijwabu oksijini. Oku kwenzeka ngokusebenzisa ukuhla kwireyithi entliziyweni, ukuhla contractility, yokwandisa ukuzala nokuphucula ubonelelo igazi. Ngenxa yokwanda xi ukuzala kwi ventricles kunye stretchability zihlunu esiqwini oxygen imfuno nande.

Ngokuphathelele iimpawu antiarrhythmic le medicament, kungenxa ekupheliseni izizathu ezibangela arrhythmia (ukusebenza kwenkqubo onovelwano, tachycardia, lwegazi, ukwanda kwinkampu yoxinaniso). Kwakhona, ichiza abangaphangeliyo AV-Uhanjiso kwaye kunciphisa izinga excitation of pacemakers.

Ziziphi ezinye iimpawu ezendeleyo iziyobisi "Bidop 'na? Imiyalelo yokusebenzisa, inkcazo, ncomo, iingcali zithi xa uthatha ngokwemithamo avareji kwezonyango zesixhobo, njengoko kuchasene kwi non-uyakhetha β-blocker abangathathi ngokukhawuleza kakhulu ukusebenza ngomhla amalungu ukuba receptors β2-adrenergic (nepancreas, izihlunu, amathambo-uhlobo nemisipha imithambo peripheral , wesizalo kunye ityhubhu inyumoniya), kwakunye nethe carbohydrate. Ngaphezu koko, abaqondanga isiyobisi igcina ion isodiyam, nangamandla wesenzo atherogenic ufana propranolol.

Entshukumo Ipharamitha ichiza

Ziintoni iimpawu kwikinetiki le "Bidop 'iziyobisi? Baqinisekiswa musa ukunika impendulo yalo mbuzo. Ifumaneka kuphela imiyalelo. Ngokutsho oku, emva kokufumana medicament kwakhe acatshulwe egazini nge 80-90%. Ukutya ukutya alunasiphumo kwi kule nkqubo.

Le xi ubuninzi isithako esebenzayo egazini kubhalwa emva kweeyure 2-3. Eli chiza sibopha kwiiproteni plasma kwi 30-32%. Yinto abapasileyo amahle abangalunganga umqobo igazi-ngobuchopho kunye ngumkhaya.

Malunga ne-50% ye ichiza aguqulwe esibindini. Oku kuvelisa metabolites phantse engasebenziyo.

Isiqingatha-ebomini medicament ifikelela iiyure ezili-12. Malunga nama-2% beziyobisi salawo kunye enyongweni malunga 98% - yi nezintso.

Ubungqina obubonakalayo buxela

"Bidop" - sisiyobisi kuphela iqinile, kodwa anti-anginal kunye nearhente anti-arrhythmic. Ngoko ke, oko kumiselwe kunye nokuphelisa lwegazi kunye ukuthintela uhlaselo exacerbation of angina izinzile.

Izimo umfutho

Ngoku uyazi ukuba kutheni ufuna amayeza enjalo, njengoko "Bidop". Iimpawu ziye uchazwe apha ngasentla. Noko ke, ichiza ekuthethwa Akuvunyelwe ngokungqongqo ukuba amisele:

• athuke;
• ukuyisonga;
• Ukungaphumeleli nokoyika intliziyo;
• nokudumba pulmonary;
• ibloko sinoatrial ;
• AV-ukuvimba yesibini okanye isidanga lesithathu (ngaphandle electrostimulator);
• syndrome sinus ogulayo;
• bradycardia;
• ukusilela decompensated ezingapheliyo wentliziyo, oko kufuna unyango inotropic;
• isifo Raynaud kaThixo ;
• hypotension;
• lactic metabolic ;
• Ulawulo ngaxeshanye monoamine oxidase inhibitors (Mao ngaphandle B-mode);
• cardiomegaly (ngaphandle ukusilela intliziyo);
• isifuba inyumoniya kunye COPD kakhulu;
• utshintsho kwegazi peripheral, ingakumbi kwi zigaba ezithile;
• pheochromocytoma (ngaphandle kokuthatha alpha-blocker);
• zegazi le into ichiza okanye enye beta-blocker;
• ukunyamezelana lactose, malabsorption galactose / glucose yelactose ngxaki;
• kweminyaka.

sabelo ngokucophelela

Iimpawu "Bidopa" isicelo zidweliswe imiyalelo apha. Kwakhona wathi ngononophelo kakhulu, eli chiza omiselwe izigulana seswekile, ukusilela kwezintso okanye hepatic, uhlobo esinganyangekiyo, myasthenia gravis, ukhwekhwe, hyperthyroidism, AV-kuvalwe iindlela kumlinganiselo yokuqala, Prinzmetal angina, ukudakumba, aleji, imbali ukuthobela ukutya ngokungqongqo nokuba abadala yobudala.

Indlela kunye umthamo medicament

Kuba yintoni injongo kunye nendlela yokusebenzisa amayeza emiselweyo "Bidop"? Iimpawu zibonisa ukuba ukusetyenziswa, ingqeqesho beziyobisi zithiwe thaca kweli nqaku.

Thabatha icwecwe ngomlomo ekukhethwa kusasa ungatyanga. Akufunekanga ukuhlafunwa, kungenjalo uya konakalisa ukutyabeka film.

Le umthamo kwiarhente alukhethileyo rhoqo ngabanye. Ukuze wenze oku, qiniseka ukuba udibane nogqirha wakho.

Ngoko ukugcina indlela ezithatha ichiza "Bidop"? Iimpawu zibonisa ukuba ukusetyenziswa - gxebe, ubukho babo - yinto ebalulekileyo yokwenza ngenjongo iyeza.

Ukuze kuthintelwe ukuhlasela nokoyika angina sifuba kwaye bezinzile phantsi phambi izigulane lwegazi banikwa idosi yokuqala iziyobisi ngokulinganayo mg-5. is he taken yonke imihla, kanye.

Ukuba kuyimfuneko, isixa echaziwe lanyuka ukuya kwi-10 mg. Kule ubuninzi reception egciniweyo.

Elona nani liphezulu ngemihla idosi "Bidop" medicament 20 mg.

Xa abantu abane umsebenzi kidney kakuhle, ngokunjalo nezifo ezinzima zesibindi idosi iphezulu yi-10 mg ngosuku.

Ukulungisa nesixa amayeza abadala akufuneki.

imiphumela izigelekeqe

Yintoni iziphumo ebezingalindelekanga kunokubangela amayeza "Bidop"? Baqinisekiswa zibonisa kukuvela neziphumo ethile egwenxa kunokwenzeka. Zezi:

• amehlo owomileyo, ukungaboni, yehlisa izinkcwe, conjunctivitis.
• hypotension intolerance, AV-block, ukuhla olomeleleyo koxinzelelo, ukuhla contractility engabalulekanga, sinus bradycardia, ukuphazamiseka Uhanjiso iqhosha izihlunu, arrhythmia, iimpawu ukusilela imbonakalo yomsebenzi kwentliziyo (chronic), vasoconstriction, iintlungu esifubeni.
• Ukudinwa, ubuthathaka, ukudinwa, ukuphazamiseka kokulala, ukudideka, myasthenia gravis, isiyezi, amabi, paresthesia kwi yesiqephu, ukudakumba, ukuxhalaba, intloko ebuhlungu, iingcangcazela, nemibono, ukuxhuzula.
• ukuxinana ngeempumlo, ukuphelelwa umoya ngexesha uthatha amachiza ngeedosi eziphezulu, okanye abantu ukuthambekela bronchospasm kunye laryngospasm.
• Isicaphucaphu, hepatitis, kome emlonyeni, ndeva enxamnye, emesis, ukuphazamiseka kwesibindi, ukuqhina, hypertriglyceridemia, iintlungu esiswini, urhudo, hyperbilirubinemia, ukwanda zesibindi enzyme lamanani.
• Exacerbation of ukhwekhwe, reactions psoriasiform, isikhumba ukuba bomvu, irhashalala, ukwanda ukubila, alopecia.
• Hyperglycemia, chaza hypothyroid, hypoglycemia (abantu abasebenzisa insulin).
• Thrombocytopenia, agranulocytosis, leukopenia.
• Arthralgia, kunciphise amandla, lumbodynia, buthathaka yobuntu, torakalgiya, ukurhoxiswa syndrome.
• Urticaria, pruritus, angawokubhuda.
• Bradycardia, naphakathi-zesibeleko abazizidalwa ngokukhula.

iimpawu libanda

Oko yayingako imiqondiso icala awayezibona "Bidop" amathamo aphezulu ichiza? Iimpawu zibonisa ukuba ukusetyenziswa kwale mali asingabo imiqathango kuphela kunye nemiqathango ukusetyenziswa kwayo. Kubalulekile ukuba bazigcine zonke umthamo ichiza, apho babenikelwe ngugqirha khona. Ukuba ngoyaba eli cebiso, isigulane bangafumana iimpawu ezifana libanda, njengoko bradycardia, arrythmia ventricular, iibhrashi cyanosis, arrhythmia, bronchospasm, AV-yaye kuvalwe, vertigo, uxinzelelo oluphezulu drop, niphele, insufficiency ezondeleyo umsebenzi intliziyo, unditsho, ubunzima zokuphefumla hypoglycemia.

Ukuze ukususa States wahlamba isisu nomonde, chelators kunye nokunika unyango kwangumqondiso yenziwa.

imithi

Kuyinto iyahambisana ezinye iindlela "Bidop" (drug)? Ukususela oko eli yeza, siye safumanisa. Nangona kunjalo, xa zidityaniswe namanye amachiza kufuneka isetyenziswe ngokuqaphela okukhulu.

"Bidopa" Xa butofelwe "Phenytoin" ukulungiselela, kwakunye kusetyenziswa iindlela ngenxa yokwanda isiphumo inhalation Ukubulawa cardiodepressive.

amachiza Radiopaque iodine aqulethe yolawulo efakwa kwandisa umngcipheko basabele anaphylactic.

"Bidop" ngokufuthi kugqiba iimpawu yokuvela hypoglycemia. Kwakhona kwandisa yoxinaniso of xanthine kunye lidocaine egazini.

Sympatholytics, womchamo, "Clonidine", "Nifedipine", "Hydralazine", kunye nezinye iziyobisi umfutho nodibaniso 'Bidopom "kukhokelela ekuncipheni olomeleleyo ingcinezelo.

Tetracyclic kunye lakhula tricyclic, kwakunye ethanol, hypnotics, nadlamkisayo kunye antipsychotics kwandisa CNS kukudakumba.

izincomo ezithile

Yintoni isigulane kufuneka bazi phambi kokuthatha iipilisi 'Bidop "? Izimvo oogqirha bathi ekuqaleni konyango, izigulane kufuneka ukuba babenonophelo nenkathalo ulawulo endleleni nini.

Lawula abantu abathabatha ichiza phantsi ingqalelo, kuquka yokulinganisa xi kunye ukubetha neempawu, kunye nokumisela amaqondo eswekile yegazi kunye nokuqhuba ECG. kufuneka abadala ukuba ukulandela umsebenzi kwenkqubo kwezintso.

Phambi unyango kuyimfuneko ukwenza uxilongo komsebenzi nokuphefumla kwizigulane kunye imbali imbali miphungeni.

Xa unyango kwezigulane pheochromocytoma lwengozi wegazi ngamazwi.

Xa iintshayi beta-blocker olusebenzayo kangako.

Ukuba ufuna ukuqhuba utyando ezicwangcisiweyo, amayeza kufuneka ayekiswe iintsuku ezimbini phambi Ukubulawa jikelele.

Ngophuhliso uxinezeleko, unyango kufuneka bupheliswe.

Akuvunyelwe ukuba ukuphazamisa kakhulu unyango ngenxa nengozi eyonyukileyo iposi engabalulekanga okanye arrhythmia wavakalisa. Le medicament itshitshisiwe ngokuthe nokwehlisa ithamo iiveki ezimbini okanye nangaphezulu.

Tablets "Bidop": nabalingani kunye neendleko

Ukuba kuyimfuneko, ingqalelo ichiza singavalwa ngokusebenzisa ezifana "Bisokard", "Aritel Kor", "Tiresias", "Aritel", "Niperten", "Bidop Kor", "Kordinorm", "Biprol", "Coronal", "START_ITALICJ "" Corbis "," Bisogamma "" Concor "," bisoprolol "" Concor Kor "," Bisomor "," bisoprolol-OBL "," bisoprolol-Teva ".

Indleko yale antianginal, antiarrhythmic kwaye umfutho iziyobisi imalunga 250-300 engange (tablets 28).

Ukubuyekeza ku amayeza

Ngoku, uyazi, ukusuka apho ichiza nga kubhalwa njenge "Bidop". Iimpawu zibonisa ukuba ukusetyenziswa, ncomo yabathengi le medicament kwi izixhobo thaca kweli nqaku.

Izithuba izigulane kubonisa ukuba isenzo ingqalelo indlela ephumelelayo kakhulu. Tablets "Bidop" ngokukhawuleza ekunciphiseni uxinzelelo kwaye buthathaka zonke iimpawu zesifo sentliziyo.

Nakuba kunjalo, kufanele kuqatshelwe ukuba eli chiza kuvamile unobangela neziphumo ebezingalindelekanga. Basenokuba esinokubakho kuye onke amalungu kunye neenkqubo.

Kufuneka kwakhona uqaphele ukuba-20% yabantu abane angina, sisixhobo nokungaphumeleli kwawo. Oogqirha ukubaqononondisa lo ubukho ngokukhawuleza ngenxa yamafutha coronary, kwakunye yobungakanani ukuzala le ventricle ekhohlo.

Xa kungekho isiphumo isigulane kufuneka ubone ugqirha yokuqeshwa kwanonyango.