"Dekapeptil": imiyalelo ukusetyenziswa, ukwakheka, kubonakala kunye Izimo

Indlela ukusebenzisa amayeza "Dekapeptil"? Imiyalelo yokusetyenziswa kweli chiza iya thaca ngezantsi. Uza kufunda izinto ezibonisa ukuba ukusetyenziswa kweziyobisi, analogs yayo, kunye nezinye iziganeko ezibi.

"Dekapeptil": inkcazelo ichiza, ukwakhiwa kunye nefomu

medicament kubhekwe wathengiswa inaliti ecacileyo ezingenambala ngaphandle kokuba akukho ivumba kunye ukungcola.

Icandelo iphambili yale ichiza triptorelin acetate. Ukongeza, oko kuquka izinto ezifana acetic acid glacial, sodium chloride namanzi ngenaliti.

Thenga isisombululo "Dekapeptil" ifoto ukuba thaca kweli nqaku kuba iisirinji, ezineengqayi, gqibezela inaliti, apho zipakishwe ngendlela iiseli nentaba kunye iibhokisi zekhadibhodi, ngokulandelelana.

Isenzo ichiza (imithi)

Yintoni na isisombululo "Dekapeptil"? Imiyalelo zokusetyenziswa ingxelo ukuba analogu zokwenziwa of GnRH, okanye-kuthiwa hormone gonadotropin-lokukhululwa.

Emva zolawulo into esebenzayo iziyobisi yenza ukwanda kwinqanaba LH kunye FSH egazini, nto leyo ekugqibeleni kukhokelela ekwandeni ezidlulayo kweli xi hormone ngesondo. ukuvusa rhoqo kwesi yebhinqa (umz, xa isicelo rhoqo iziyobisi) ezonto ukusebenza kwamabutho gonadotropic. Isiphumo lweziphumo ezinjalo linciphileyo inani emzimbeni (sex) ukuba ngxaki okanye postcastration. Ezi ziphumo ingathityazwa.

Uphononngo kwizilwanyana laboratory wabonisa akukho mutagenic okanye iziphumo eteratogenic ingqalelo iziyobisi.

Le pharmacokinetics of inaliti zeziyobisi

Yintoni pharmacokinetic iimpawu uphawu isisombululo "Dekapeptil"? Imiyalelo Sebenzisa ithi kwimizuzu yokuqala 50-90 emva lolawulo beziyobisi egazini ifikelela triptorelin layo incopho. Ezinye yoxinaniso weli abahlukene kunciphise (emini).

Ixesha isiqingatha ubomi yecandelo eziphambili imizuzu 18.7. Malunga ne-4% of triptorelin ivela kwi umchamo ngohlobo ingaguqukanga.

Kufuneka kuqatshelwe ukuba pharmacokinetics zovavanyo zeziyobisi zenziwa ngabantu unesifo be fibroids zesibeleko okanye endometriosis, kwakunye amavolontiya iinkunzi esempilweni izigulane carcinoma ye endlaleni.

Ubungqina obubonakalayo buxela ukuba zolawulo isisombululo injectable

Kuba yintoni prescribers "Dekapeptil" injongo? Iimpawu zokusetyenziswa isisombululo ukuba amabhinqa:

• fibroids wesizalo;
• nenzalo therapy usebenzisa ubuchwepheshe zokuzala (umz, transfer umbungu, IVF);
• endometriosis.

Ke amadoda, oko sisixhobo Kucetyiswa ukuba unyango kwangumqondiso hormone-oxhomekeke carcinoma elichubekileyo endlaleni.

Siphelisa ukuqaliswa ichiza amadoda kunye nabafazi

Kwezinye iimeko, awukwazi ukungena isisombululo "Dekapeptil"? Imiyalelo yokusebenzisa zibonisa ukuba le ichiza contraindicated abafazi:

• ngelixa lwebele-lweehagu;
• nokukhulelwa;
• obubonakala kwezonyango kunye nomngcipheko kwamathambo.

Kufuneka kuqatshelwe ukuba ngononophelo ichiza esetyenziswa ekwenziweni lwenkqubo izigulane IVF kunye amaqanda polycystic (ngamanye amazwi, ukuba inani zoboya, ekuye kwagqitywa ultrasound, kuba ngaphezu kwe-10).

Kubantu besini eyomeleleyo ichiza kujongwa contraindicated ku:

• nge kuthenwa ensimbi (phambi);
• prostate carcinoma (hormone ezizimeleyo).

isithintelo jikelele le ndawo kuyiwa sisixhobo hypersensitivity ukuya triptorelin kumguli okanye namanye amacandelo ichiza.

Isisombululo "Dekapeptil": imiyalelo yokusebenzisa

Olu nyango ilungiselelwe yolawulo ongama. Xa endometriosis, umhlaza wesinye umhlaza zesibeleko ichiza elo lilawulwa isixa 0.5 mg / ML kanye ngosuku iveki yonke. Ngosuku 8 Kwathi ukuba idosi nokugcinwa 0.1 mg / ML kanye ngemini.

Xa unyango le arhente kufuneka aqhube ultrasound kunye nokuhlola Isanti fibroids kunye endometriosis nakujoliso olutsha.

Xa medicament inkqubo-IVF ilawulwa ngokungqinelana ezisemthethweni (inokuba mfutshane okanye ultrashort). Ukuze kuthintelwe isitofu site ngayo post-ziphene ixesha utshintsho ngasinye.

ukusebenzisa Xa isisombululo "Dekapeptil Depot"? Imiyalelo Sebenzisa uthi ukuba esi sixhobo iboniswe ngethuba lekhosi elide unyango. Kwakhona ilawulwa kwesikhumba kummandla esiswini okanye intramuscular 1 rhoqo ngeentsuku ezingama-30.

Isisombululo uzilungiselele yayisetyenziswa ngoko nangoko. Unyango Endometriosis kunye zesibeleko myoma iqala kwimihla lokuqala komjikelo. Olu nyango kufuneka kuhlala iinyanga malunga 3-6. Xa uthomalaliso umhlaza prostate kwakhona kwenzelwa ixesha elide.

Xa IVF iziyobisi "Dekapeptil Depot" ezilawulwa kanye ngeentsuku ezithile komjikelo.

Izenzakalo by-lomsebenzi

Ebangela reactions ezibi isisombululo "Dekapeptil"? Imiyalelo, ukubuyekeza baxele ukuba iziphumo ebezingalindelekanga, owayebonakele kwisiqalo lwesicelo kweli chiza ngenxa yokuncipha kwenani hormone ngesondo egazini, leyo ekugqibeleni kukhokelela kuphuhliso iimpawu ezifana exinezelekile, isimo lability, ikhanda njalo, buthathaka yobuntu, ukuphazamiseka kokulala , komzimba, inzuzo ubunzima, kwaye ukubila ukwanda. Ukongeza, ezi nguqu zilandelayo ziye zabona kwezinye izigulane:

• ekuphazamiseni womchamo, paresthesia, iintlungu ngexesha neentlobano zesini;
• ukungaboni, iqolo, ukuba buthathaka kwezihlunu;
• abafazi - ukopha zesibeleko kunye nokoma lobufazi;
• amadoda - gynecomastia, kunciphise amandla kunye nokunciphisa ubungakanani amasende;
• isicaphucaphu, siwasebenzise, ukungabi namdla, ukurhawuzelela;
• fever, hypercholesterolemia, iintlungu bone okubangelwa metastases;
• myalgia, spinal intambo ucinezelo, anaphylaxis;
• arthralgia, iintlungu kwi ichiza inaliti, demineralization bone (kunye nokusetyenziswa ixesha elide);
• zamanzi node yesinye, thrombophlebitis, ukudumba iinyawo;
• ukulahleka uboya apha emilenzeni, esifubeni nasezingalweni, nokunciphisa ukukhula neendevu.

Kufuneka kuqatshelwe ukuba zonke ezi ziphumo bezingalindelekanga shwaka ngoko nangoko emva kokuphela unyango.

imithi, ngaphezulu

Ngaphezulu ingqalelo iziyobisi uyalandelwa. Ngophuhliso naziphi na iimpawu ezingalunganga kwi imvelaphi ngokwemithamo ezingaphezu amayeza kufuneka kwenziwe unyango nomqondiso.

imithi "Dekapeptil" iye ayasekwa kunye nezinye izinto.

ulwazi oluthile yezigulane

iziyobisi unyango "Dekapeptil" kufuneka kube phantsi kolawulo olungqongqo lwe umgangatho hormone ngesondo egazini.

Abasetyhini kufuneka enze uphando ukwenzela ukuthintela ukukhulelwa kunokwenzeka. Ngexesha ukusetyenziswa kweziyobisi akwamkelekanga ukusebenzisa zokucwangcisa hormone, kwakunye amalungiselelo equlathe estrogen kukodwa.

Isigulane kufuneka Kucetyiswa ukuba ebudeni unyango ingqalelo sexesheni kweziyobisi iya kuba ndingekho.

Ukusetyenziswa kwale sixhobo emadodeni kungakhokhelela ukonakala okwexeshana imeko yabo. kufuneka ubone nangoko ngugqirha isenzeko iimpawu ezimbi.

amachiza afanayo

Yintoni indawo isisombululo amayeza "Dekapeptil"? Analogue ukuba eli chiza zicwadi kunzima kakhulu ukufumana, ngoko ke inkqubo efanayo kufuneka asebenze kuphela ugqirha onamava.

Ngokutsho iingxelo ezithile iingcali, amayeza nako kuqwalaselwa indawo ndlela ilandelayo:. 'Zoladex', 'Buserelin Depot "," Diferelin "," triptorelin "

Izimvo sisombululo ziphene

Okwangoku, kuba unyango lwe endometriosis, uhlelo zokuzala kunye nezinye izifo ezininzi kakuhle kwaye ophumelelayo agonists incindi yedlala gonadotropin-lokukhululwa. Ezi ziquka iziyobisi ezifana "Dekapeptil", "Diferelin ',' Zoladex 'kunye nabanye. Nakuba kunjalo, kufanele kuqatshelwe ukuba iindleko eziphezulu mali ezinjalo awubavumeli ukuba kakhulu ukuba kusetyenziswa yezonyango. Kulo mba, izimvo isicelo sabo, akukho kakhulu kunene.

Ngokutsho iingxelo leengcali, ichiza "Dekapeptil" amaninzi ezimiselweyo unyango fibroids zesibeleko (ixesha iinyanga 5-6). ukusetyenziswa enjalo medicament iza kukhokelela kukuba kubekho ukuncipha umthamo zesibeleko kunye ubukhulu ezalathelwe uphuhliso. Okulandelayo enze uqhaqho. Ngoko ke, unyango "Dekapeptilom" yaye emiselweyo njengoba kulungiselelwa ipreoperative.

Izigulane ezininzi bathi emva kokuba ukuqaliswa isisombululo badla kwaphawulwa kuyo inaliti intlungu, ukurhawuzelela kunye bomvu. Kwakhona yintloko, komzimba, efuna nokudinwa.

imibiko emihle ngale isixhobo rhoqo ashiye nabafazi usebenzisa "Dekapeptil" IVF protocol. Ngenxa eli chiza kwiimeko ezininzi le nkqubo nokuphunyezwa ndiseyimbumba kulo isibeleko iphela ngempumelelo. Of icala iziphumo wakhankanya sex ukufikelwa intle ashushu kunye ukubila.