Phosphatidic acid. Yolungelelwaniso kunye nokubaluleka emzimbeni

Kweli qela isakhiwo weekhemikhali, phosphatidic acid na phospholipid zilula.

Le into yenye yayiba phosphoglycerides yokucolwa in vivo.

Olu udidi kwezinto inikwe ingqalelo kakhulu kwi nasekufundweni kwemisebenzi umqondiso iikhompawundi chemical.

Ukuza kuthi ga ngoku, ukuya ekupheleni akucaci zonke links nethe ye asidi phosphatidic, ingakumbi, ukuba kuseyinto umbuzo indlela lonxibelelwano data transmission umqondiso, ngokunjalo malunga ubukho asidi phosphatidic iipropati ionophoric.

Yindibanisela phosphatidic acid

Phosphatidic acid Ukwakheka iphenjelelwa phospholipase D. Le iklasi enqanda unendima ephambili Yindibanisela asidi phosphatidic. Njengoko compound gqitha elifutshane elide imichiza, kamva iziyobisi phantsi kwempembelelo fosfogidrolazy hydrolysed ukuba diglyceride (ukusabela dephosphorylation).

Xa ukuthetha phosphatidic acid efanayo transcriptase ukuba inguqu diacylglycerol, nto leyo elenza kumjikelo hormone umsebenzi ngayo isilumeki le kinase enzayim esika iiproteni C.

Yindibanisela phosphatidic acid kwenzeka adipose kwithishyu. Le nkqubo iqala kunye ukufunyanwa kwi adipocytes (iiseli zomzimba adipose) fatty senziwa haydrolisis kwamafutha (ubukhulu becala, lipoproteins ingxinano ephantsi kakhulu). Ngaphakathi esiseleni, kunxityelelwana glycerol-tri-phosphate, fatty eziguqulelwe kuqala lysophosphatidic acid, ukusuka apho phosphatidic acid kamva kwakhiwa.

Formula kuyilwa ngoko glycerophospholipids phosphoric equlathe elwa okunamafutha acid, glycerol, kunye anions nitrogen-equlethe.

Meaning of phosphatidic acid

Kuye kwafunyaniswa ukuba phosphatidic acid yinto ebizwa ngokuba yi-ngendibaniso siphawula, oko kukuthi, abo ukuba umsebenzi yabameli kwi ukudluliselwa kolwazi endleleni umkhosi esandleni sakhe. Ngokukodwa, oko ikhonkco ephambili ekudluliseni ezi zimpawu kwi plant cells:

• cytokinin;
• osmotic ukuba unalo ixabiso kuphuhliso impendulo yeselula kule hlobo ntshikilelo.

Ngexesha amalinge bekubonakalisiwe ukuba izinga ezimbaxa iiseli baboniswa eziphilayo zezityalo izinto yayintsholongwane eyosulela kwandisa kakhulu. Le yokusabela ibangela:

• zeleka Osmotic.
• amaqondo Low.
• Ifuthe izithako ezithile ezisebenzayo ukuba imvelaphi imifuno (phytohormones).

Ngenxa yoko, kunokwenziwa isigqibo kwi inxaxheba phosphatidic acid kunye metabolites zalo reactions entsonkothileyo onoxanduva kwingcamango ephilayo kwiimeko uxinezeleko.

Ngaphezu koko, kwakusazeka ukuba phosphatidic acid kubalulekile ukuba uthutho protons kunye abasabela ion calcium ngokusebenzisa inwebu zemithambo-luvo kunye imicu kwezihlunu. Ngako oko, phosphatidic acid kunye umsebenzi Mnikeni ionophore (emane: ngokuba ion calcium kunye protons).

mechanism transduction

Nangona injongo phosphatidic acid ezifumaneka ngqo indlela (indlela) of ugqithiso signal nangoku zixoxwe kwaye ufuna iinkcukacha.

Kodwa akukho mathandabuzo ukuba transduction leyo kubulela wenziwa nokukwazi phosphatidic acid, echaphazela isakhiwo yeselula ye-inwebu, i inwebu ukulawula umsebenzi enqanda, kwaye kananjalo inxaxheba intsebenziswano kunye molekyuli inwebu protein zeselula.

Ukusebenza phosphatidic acid

Ucwaningo umsebenzi antioxidant avela of phosphatidic acid, eziqhutywa kuphononongo kweenkqubo umfuziselo ebandakanya izinto eziphilayo lubonise ukuba ekuthiwa-biomimetics acid phosphatidic ilifa nobuninzi antioxidant ukuchumisa amanyathelo.

ulwazi olubanzi kwicala yesenzo of phosphatidic acid ikuvumela ukuba bayisebenzise kwaye metabolites yayo ekuvelisweni kwezinto eziphilayo esebenzayo eyenzelwe ukuphucula intsebenzo kunye nonyamezelo eziseleni.

Owenza kwinqanaba zeselula, loo khompawundi musa ukukhuthaza, kodwa ukubuyisela kuphela iiseli; indawo ebalulekileyo ukunciphisa umngcipheko yeziphumo ebezingalindelekanga elibi.