Izitatimende zokunciphisa i-cholesterol zingabangela isifo sikashukela kwaye sichaphazele ingqondo?

Kutheni i-cholesterol eyoyikisayo iyethusa kuzo zonke ikhonkco? Yintoni ephosakeleyo kulo nxu lumano lwendalo kunye nantoni na ukuba ininzi yeengcinga zendalo zenziwe ngeenxa zonke? Mhlawumbi isizathu sokuba ukungabi nathandwa kwe-cholesterol kusekuhlaleni okukhulu okuchasayo, okuvela kwiinkampani ezikhokelayo zokurhweba. Emva koko, ukuba banemveliso, kuyimfuneko ukufumana umthengi othembekileyo. Kwaye abantu abaninzi bakholelwa kwiingxelo zoogqirha, imali eyongezelelweyo iya kufakwa kwingxowa-mali yabakhiqizi.

Inzuzo yeMillion-dollar

Iitatimins ziyizidakamizwa eziphantsi kwee-cholesterol. Kuphela kweli qela lamachiza e-drug pharmacological lifumana imali yeebhiliyoni ezigidi. Kodwa ukuba uhlalutya iziyobisi, esoloko zichazwe oogqirha, kukho umendo onobuchule: imimiselo iboniswe kwisiqingatha esihle semimiselo emiselweyo. Njengoko ubona, kukho umzekelo othe ngqo.

Icandelo leyeza leyeza lilahlekelwa ukuthembela kwezigulane

Kwiminyaka embalwa edluleyo, abantu abaninzi (ngezizathu ezahlukahlukeneyo) abasayi kuba nethemba kwi-pharmacologists. Oku kungenxa yezifundo ezininzi ezijoliswe ekufundeni iziphumo zamachiza athandwayo emzimbeni womntu. Njengomthetho, iingcali ezizimeleyo, zinyamezela isigqibo esididekayo. Uninzi lwapapashwa ngamapilisi alummangaliso aluphilisi, kodwa luqhwaba abantu.

Iinkcukacha ezintsha ezityhaxisayo

Kungekudala kudlulileyo kwi-American Journal of Physiology zapapashwa iziphumo zoluphando olutsha, oluchaza ukuba i-statins ingabangela ukuguga ngaphambi komzimba. Ukusetyenziswa kwexesha elide kweziyobisi ezinciphisa i-cholesterol egazini, ehambelana nemiphumo emininzi yempilo. Isigulane esigcina ngokucacileyo imimiselo yokungena kwiingcipheko zoogqirha ukuze ujwayelane ne-myopathy (ubuthakathaka obuthakathaka besifo), ezinye izifo ze-neurological and diabetes mellitus.

Ababhali be sifundo baphumelele ekubonakaliseni iziphumo ezinobungozi zonyango

Iimpawu zinefuthe elibi kumaseli e-mesenchymal stem, anembopheleleko yokwakhiwa kwamanani omzimba kunye namathambo. Ezi zi yobisi zenza utshintsho kwinqanaba lokubonakalisa i-DNA yokulungisa izakhi zofuzo. Yisi sizathu esibizwa ngokuba yiyona nto eyona miphumo echaphazelekayo yeclini. Kukholelwa ukuba iimimiselo zinciphisa inani lamacwecwe kwizigulane ezinesifo senhliziyo. Kule nto, icandelo elihle kwaye lithetha iinkampani zonyango.

Ukuba isigulane sicinga ukuba inqanaba elongezelelweyo le-cholesterol liza kumbulala ngokukhawuleza okanye kamva, uya kuyinyamekela ukusetyenziswa rhoqo kweziyobisi ezinefuthe le-hypocholesterolemic. Nangona kunjalo, ngakwelinye icala, akuncedisi kubavelisi ukuxelela abantu malunga nemiphumo emibini yeemveliso zabo. Yingakho iingcali zicebisa ukuba sicinge kathathu ngaphambi kokuba sivumelane neziphakamiso zegqirha. Kwabanye abantu, iziphumo ezingasentla ziba yingxaki enkulu.

Yintoni ekusebenziseni ixesha elide leemimiselo?

Abantu abangayazi ukuba zeziphi iingxaki zesistim se-cardiovascular should not infle ingxaki kwizinto ezingekho. Kule meko, ukunciphisa i-cholesterol izinga (ngokukodwa kwimvelaphi yolawulo lwexesha elide) kuquka umngcipheko wokwakheka kwe-cataract. Ezi zi yobisi azisetyenziswanga njengesilinganisi sokukhusela, ngaphandle koko, zonke iingozi ezinobungozi kufuneka zilinganiswe. Ukuba iziyobisi zeli qela zinemiphumo emibi kwiiseli ezibafileyo, oku kubangela ukunciphisa ukukwazi ukwahlula ama-tissue amasha.

Ezinye iziphumo

Okwangoku, izazinzulu ziye zaqhuba izifundo ezininzi ezijoliswe ekufundeni umphumo weemimiselo kwimpilo yabantu. Ukuba sishwankathela izigqibo zonke zovavanyo lwezenzululwazi, kuvela umfanekiso ophazamisayo. Ingqikithi, ukususela kwizidakamizwa ze-hypocholesterolemic, iziphumo ezingaphezulu kwama-300 kunye nezingozi ezisemngciphekweni zifumaneka. Sichaza kuphela izinto eziphambili: umngcipheko wokuba nomhlaza, i-cataracts, uhlobo lwesi-2 lwesifo sikashukela, ukuphazamiseka kweendleko kunye nokukhathazeka kwengqondo.

Uphando olunzulu lufumene ukuba ukusetyenziswa kweminyaka elishumi yemimiselo ngamaphesenti angama-83 kwandisa ingozi ye-carcinoma. Ewe, ukuba sicinga ngamanani eengxaki zomhlaza wesibeleko, iifom ziyancipha ngakumbi: iziyobisi ze-hypocholesterolemic zinyusa ukwanda kwengozi yokuphuhliswa kwezicubu ezibi ngamaphesenti angu-97. Njengoko ubona, abafazi kufuneka babe ngabanobuqili.

Ekulweni ne-atherosclerosis

Ukuba uxhalabele kakhulu ngokunciphisa izinga le-cholesterol egazini, kufuneka ukwazi igama elibi "i-atherosclerosis". Esi sifo singapheliyo, kubangelwa ukuphulwa kwe-lipid metabolism kwaye kuthintela imirhobho kunye nemithambo yegazi. Iipilisi ze-cholesterol zenziwe ngendlela yeeplates, ezikhokelela ekuqiniseni iindonga zeempahla kunye nokulahleka kwazo. Kuqhelekile ukuba ucinge ukuba i-statins ingakwazi ukulwa nemeko yegazi, kodwa iingcali ezizimeleyo ziphinde zitsho ngenye indlela. Ngokwenzululwazi, eli qela leziyobisi livuselela i-atherosclerosis kwaye likhokelela entliziyweni yokungaphumeleli kwezigulane.

Umgqugquzeli wesifo sikashukela

Ngo-2012, kwakukho ubudlelwane ngokuthe ngqo phakathi kokuthatha i-statins kunye nokuqala kohlobo lwe-2 lweswekile. Iingcali zixhalabele ngokubhekiselele kwimeko yezemicimbi kwaye zincenga abenzi ukuba zichaze oku kwicandelo "lemiphumo" kwiphakheji. Ileta eyisixwayiso iya kuba yintsimbi ye-alamu ebantwini eneenkcukacha eziphezulu kwi-diabetes.

Ngaba kukho enye indlela?

Enyanisweni, i-cholesterol ibalulekile kumntu. Liyinto ebalulekileyo kwimimbrane yeseli kwaye inempembelelo enkulu kwi-hormone ye-steroid kunye nokuveliswa kwe-vitamin D. Nangona kunjalo, inyama, iilekese kunye nemveliso equkethe amafutha atshintshe anefuthe elibi kwisakhiwo seeseli. Umsebenzi we-cholesterol ukubuyiswa kwezicubu ezinobungozi. Ngoko ke, kufuneka sikulwe nxamnye nomphumo, kodwa ngenxa yeso sizathu.

Kuyaziwa ukuba ukutya komntu wanamhlanje kubandakanya inyama kunye nokutya okucwangcisiweyo. Ngelishwa, saqala ukulibala ngokutya kwezityalo. Kodwa oku akulungile, nangona uqala ukuphikisana kwaye ucacise ukulinganisa kwabantu bamagxa njengomzekelo. Asinakukwazi ngokuqinisekileyo oko okhokho bethu badla, kodwa siyakwazi ukujonga kwimenyu yemihla ngemihla yezihlobo ezifuphi ezisondelene nazo. Njengoko uyazi, iinkawu azidli inyama. Kwaye, kwaye sinomathumbu okwaneleyo, oko kuthetha ukuba okokuqala kwakulungele ukutya ukutya kwezityalo.

Ukutya kwe-vegan kunika izibonelelo ezintle zempilo

Ukuhambelana nokutya kwezityalo akuboneleli nje ngeenzuzo ezithile zezempilo, kodwa kubandakanya nokuthintela izifo ezininzi ezinzulu. Ngoko, umzekelo, ukutya imifuno, unokuzikhusela ekuhlaselweni kwentliziyo okanye ngesifo, umhlaza wesifo somhlaza, isifo sikashukela kunye nezinye izifo. Ukuba ufuna ngokwenene ukukhusela imilambo yegazi, qwa lasela kwakhona umfanekiso wesondlo, kwaye ungathengi kwizitatimende ezilandelayo eziphakamileyo ze-pharmacologists.

Ungazibonakalisi rhoqo umzimba wakho kwiziyobisi, kungakhathaliseki ukuba zithini namhlanje. Sazi ixesha elide ukuba zonke iyeza zinemiphumo emibi, kungenxa yokuba baqhathanisa ukubaluleka kuyo. Kodwa ukuba ngaphandle kwemvelaphi yokuthatha ama-statins awuzange ube nempendulo yesikhashana emzimbeni, ayithethi nto. Imiphumo emibi ingabonakala kamva, kodwa iya kuba yingozi ngakumbi kunokugqithisa okulula okanye ukutywaba.