Iidakamizwa "Ursosan": imiyalelo yokusetyenziswa

Isilwanyana "i-Ursosan" sikhululwe ngendlela yeefomsile, nganye iqukethe i-250 mg ye-ursodeoxycholic acid esebenzayo. Isilwanyana sibandakanywa kwiqela leekliniki kunye nekhempikiyetha ye-hepatoprotectors, ene-choleretic, isilly-dissolving action.

I-ursodeoxycholic acid iyongezwa ngokugqithiseleyo njenge-arhente yezobisi i-lipid-lowering, i-hypocholesterolemic kunye neminye imiphumo ye-immunomodulating effect.

Isilwanyana "i-Ursosan", umyalelo wokusetyenziswa ubonisa, unempahla ye-polar, eyenza kube lula ukwenza ama-micelles angenayo isetyhi. Ngako oko, kunokwenzeka ukunciphisa amandla okugaya i-reflux yesantya sokutshabalalisa iimbumba ze-cell kwi-diagnosis ezifana ne-peptic gastritis, i- peptic esophagitis. I-ursodeoxycholic acid ingenza iimolekyuli ezimbini eziyingxenye yeembrane zeeseli ezinjenge-hepatocytes, i-cholangiocytes, i-GIT epitheliocytes, imise imisebenzi yazo, kwaye ikhulise i-micell cytotoxic.

Ukusetyenziswa kweziyobisi "i-Ursosan" kunokunciphisa izinga le- bicic acid , elonakalisa i-hepatocytes, ivuselela i-choleresis, ifuthe kwisisombululo esifanelekileyo se-cholestasis ye-intrahepatic, sinciphise i-lithogenic index of bile. Ngako oko, isilwanyana "i-Ursosan", umyalelo wokusetyenziswa ubonisa, isetyenziselwa ukutshabalalisa ama-gallstones afakwe kwi-cholesterol, ukukhusela ukutsalwa kweemveliso ezintsha kwiindawo ezinobumba.

Impembelelo ye-immunomodulating ifumaneka ngenxa yokuvimbela umsebenzi wee-antigens ezithile, ngokuqhelekileyo umsebenzi we-killer of lymphocytes. Kuye kwaqulunqwa ukuba i-ursodeoxycholic acid iyeka ukuphuhliswa kweenkqubo ze-fibrotic kwezi zi gulane ezifunyanwe ne-cirrhosis ephambili, i-steatohepatitis yobunxila, i-cystic fibrosis.

Iidakamizwa "Ursosan", isicelo

Isilwayo simiselwe:

• Nge-cholelithiasis, eqhubeka ngaphandle kweengxaki;
• Xa ukuchithwa kwama-gallstones akhiwe kwi-cholesterol kwi-gallbladder;
• Ukuthintela ukuphindaphinda kokubunjwa kwamanani emva kwe-cholecystectomy;
• Unesifo esibangela ukungabi nesifo esibangeleko esibusweni;
• Nge-hepatitis enobuhlungu;
• Ukulimala kwesibindi sesibindi;
• I-cholangitis ephambili;
• Ngezifo zesibindi ezinxulumene notywala;
• Ngokuvela kwimoya ye-steatohepatitis engekho ngotywala;
• I-cirrhosis ephambili ye-biliary type;
• I-cystic fibrosis yesibindi ;
• I-peptic gastritis kunye ne-esophagitis;
• Nge-syndrome ye-biysary dyspeptic;
• Ukuthintela izifo zesibindi ezichaphazelekayo nokusetyenziswa kwe-contraceptive ye-hormonal okanye i-cytostatics.

Isilinganisi sesilwanyana sikhethwe ngugqirha kuxhomekeke kwi-diagnostic kunye nemeko yesigulane.

Isiza "Ursosan", imiyalelo yokusetyenziswa, umphumo wecala

Ukuphazamiseka kwenkqubo yokugaya kubonakaliswa ngongcamango, ukuhlanza, isifo sohudo, ukugqithiswa, ukuphakama kwexesha elide lokuhamba kwe-transaminase ye-hepatic; Kwixesha leemvavanyo zecliniki, kwakhiwa i-gallstones ebhaliweyo.

Ezinye iziphazamiso emzimbeni zingabonakalisa njengentlungu emva, ukuphendula, ukunyuka kwe-psoriasis engapheliyo, i-alopecia.

"I-Ursosan" amayeza, imiyalelo yokusetyenziswa, ukuchasene

Musa ukulawula le nkunkuma kula macala alandelayo:

• Ngama-gallstones, aqukethe i-calcium eninzi;
• Nge-fistula ye-bile-esiswini;
• Nge-cholecystitis kwifom elula;
• Ngokungafihli kakuhle;
• Nge-cholangitis enzima;
• Nge-cirrhosis yesibindi;
• Ukungaqiniseki kwamanzi;
• Ngobunqamle be-bile ducts;
• Ngesifo esichengeni sisifo se gallbladder;
• Nge- empyema ye-gallbladder ;
• Ngobukhulu besondlo kwiziyobisi.

Xa echaza ukuba izidakamizwa ziza kutshabalalisa i-gallstones, ugqirha kufuneka athathe ingqalelo ukuba iifomethi kufuneka zibe nemvelaphi ye-cholesteric, engadluli kwi-15-20 mm ngobukhulu. Kule meko, i-gallbladder kufuneka isebenze, ihlale ikhululekile ngaphezu kwama-50%, ukwenzela ukuba ubuchule bugcinwe.