Ichiza "Tamsulosin": imiyalelo ukusetyenziswa, ixabiso, imihlolo analogue

"Tamsulosin" antidizuricescoe isenzo neziyobisi isetyenziswa lingaze inkqubo modulator wokuchama in izifo yomchamo ezibangelwa iseli-amabi prostate ngamathumba umlinganiswa. Isixhobo reaction kubonakaliswa ukuhla kancinane ngamandla kwi esihlunwini kakuhle endlaleni, kwakunye ukunyenyiswa entanyeni lwesinye. Ukongeza, kukho uyakhetha ethintela urethral alpha 1A-adrenretseptorov, kukhokelela nokuncitshiswa neziphumo waphawula indlela ezivaleke - yoko lendalo kuphuhliso adenomas.

iimpawu amayeza of "Tamsulosin"

Kukufakwa izithako ezisebenzayo ichiza phecana zesisu kunokuba ukuya kwi-100%. Ngokomfuniselo waqinisekisa ukuba ukufunxeka inyuswe xa uthatha i njengezingxobo ngoko nangoko emva kwesidlo. The degree of nokwenziwa ngokomlinganiselo ixesha elidlulileyo ukususela yokuselelwa ichiza (ngamanye amazwi, kukho kinetics yomgama). I kwincopho xi le reactants kwi plasma ukuba afezekiswa emva kweeyure ezintandathu (esisodwa 400 mg). Nangona kunjalo, eli xesha inokwahluka ngokuxhomekeke kubudala lomguli.

Kuyaphawuleka ukuba yomamkeli kwii ekuhambeni kweentsuku ezintlanu, uyazikhomba izakhi ukunyuka plasma nge 60-70%. Tamsulosin hydrochloride ngokwaneleyo kancinci engena iinkqubo pathways: ukufunxeka sikhatshwe ukuyilwa metabolites ezizinzileyo izizathu selectivity eliphezulu alpha 1A-adrenoceptor.

Ubungqina obubonakalayo buxela

Ichiza "Tamsulosin" yemiyalezo ngokucalula nokwahlula njenge-arhente yonyango hyperplasia ingozi prostatic, kwangumqondiso kakhulu (adenoma, dysuria, kunye nezinye izifo asezantsi phecana zangasese).

Ekubeni zophononongo Ababutyhila naziphi abasabela ezibalulekileyo kwezinye izinto ze wathi iqela amayeza, ngoko akukho miqobo isicelo of "tamsulosin" njengento engundoqo abangabancedani kunye zonyango ethintela uyakhetha alpha-1a adrenergic receptor.

oyidlayo okunikezelwe kunye nendlela yolawulo

Ukungabikho ukusebenza iqinile - inkalo uphawu ichiza "Tamsulosin". Imiyalelo yokusebenzisa ithi imfuneko yokukhetha ithamo nje kuphela - ngokwaneleyo ngomlomo ilawulwa micrograms 400 beziyobisi emva kwesidlo sakusasa (2 njengezingxobo / amacwecwe ezinobunzima 200 mg nganye, okanye 1 Isingxobo / tablet zalishumi 400 mg). Ngaphezu koko, eli zinga mihla mfuneko izakulungiswa, nokuba isigulane uye waphawula ukuba izinto ezinxaxhileyo engephi kwizintso okanye isibindi. Noko ke, ekuqaleni kwekhosi unyango kufuneka lwandulelwe ukuxilongwa ngqo ukuze ukuvala amathuba somdlavuza wendlala. Kwakhona ebudeni unyango uviwo mandatory efakwa.

Njengezingxobo and tablets "tamsulosin" kufuneka ayetyisi - calulo olwaphula le mvulophu unakho ichaphazele ukukhululwa izinga wezenzi esebenzayo. Ngoko nangoko emva kokuba ezithatha ichiza Kucetyiswa ukuba basele amanzi. Akuvunyelwe ngokungqongqo ukuba usebenzise "Tamsulosin" kwindawo lisalele.

ukulinganiselwa ezikhoyo Izimo

Ichiza "Tamsulosin", ixabiso apho, ngokuxhomekeke umenzi neepakethe fomati, kuyehla engange 400-1700, yenzelwe kuphela abantu. Ngoko ke, uphando imiphumela yayo ekukhuleni kosana olungekazalwa azikhange kuqhutywa ngexesha lokukhulelwa. kuphela amayeza enikwa data tablet, oko kukuthi, lokufunyaniswa "hyperplasia prostatic ebubonisayo," kufuneka abulawe kwisaveyi (nge inyanzelekile pre-test umhlaza).

Phakathi contra - hypersensitivity ukuba ichiza "Tamsulosin" (application User iqulathe uluhlu oluneenkcukacha zonke wezenzi abancedisayo). It ayinqweneleki ukusebenzisa ye uthe arhente hypotension intolerance kunye nezifo ezingapheliyo wesibindi okanye izintso (kwiimeko ezinjalo, ugqirha kufuneka ukuqikelela amancedo anokuba yosetyenziso "tamsulosin" kwaye balibeke iimpembelelo ezingalunganga ezinokwenzeka lwezifundo zonyango).

Negumbi rhoqo ukukhanya kuvumelekile nesiyezi, maxa wambi indawo karhulumente osabekayo. Abaqhubi bezithuthi kunye nabasebenzi, imisebenzi yakhe yobungcali ziquka ugrogriso lokwenzakala, kufuneka bangayeku isilumkiso kakhulu kwi ngokusetyenziswa kweziyobisi.

imiphumela emibi

Njengalo naluphi na isiyobisi, kukho iziphumo ezingalindelekanga kunye neziyobisi "Tamsulosin" (ixabiso zempilo zamadoda liphezulu, kunye negazi zincinane, kangangokuba abasabela ezibi ozakuthathwa nokungabikho ebonakalayo akukho kuyimfuneko).

Ngaxeshanye kunye nefuthe ukuphilisa kungathatha indawo:

• intloko;
• kwinwebu kwesikhumba;
• ubude sorhudo;
• arrhythmias intliziyo;
• ubuhlungu zangasese.

"Tamsulosin" Maxa wambi, analogue apho zifumaneka ngokubanzi kwimarike, ebangela izigulane ukuphuthelwa okanye, icala, ukozela ngokugqithiseleyo. Kwiimeko ezinqabe - ephula okwethutyana kwesitulo kunye buthathaka amandla.

Libanda, obubonakala kunye neutralization

Iimpawu libanda, elisuke laba sisiphumo ichiza "Tamsulosin" (imiyalelo zokusetyenziswa zilumkisa oku), oko kuthiwa oyingozi hypotension. Kwaye nangona nokwenzeka kwale meko esezantsi kakhulu, lo algorithm pfuneta kunjalo wenza:

• kwangoko inike isiguli ngokuxwesileyo;
• ukuba kuyimfuneko, a endla ntirho oluntsonkothileyo amanyathelo ezijoliswe kuqheleke nemithambo yegazi umzimba;
• ukungqinisisa nemisebenzi izintso (izixhobo uqhagamshelwano kwezindlela nyulu igazi ayisebenzi kuba isithako esebenzayo kunxulunyaniswe ngokugqibeleleyo kunye khompawundi plasma protein);
• ukuba ukugabha kwi umguli ukuze ayeke ukufakwa ngakumbi reactants (yinyaniso lavage esiswini kunye nokusetyenziswa engumzekelo laxatives);
• xa engekho Dynamics yophuculo ukusebenzisa amayeza enza nokuhamba kwegazi.

intsebenziswano Drug: uhlobo abasabela

"Warfarin" yaye "Diclofenac" kuchaphazela ngokomgangatho isantya we "Tamsulosin" ichiza yomzimba (ixabiso iziyobisi enkulu, kodwa umphumo ixabisa ngayo). Noko ke, Imigqaliselo elide malunga nokusetyenziswa odibeneyo le mithi esibhedlele hayi ikhutshwa phandle, njengesiphumo isilumkiso kakhulu kucetyiswa,. "Atenolol" yaye "Enalapril" angavumelaniyo kunye wathi eziphathekayo, "cimetidine" ikhuthaza xi "tamsulosin" plasma, yaye "Furosemide" unika japan malunga ngokupheleleyo.

Inkqubo ukuthoba uxinzelelo lwegazi nomsindo inani le medicament kwengeniso ngenxa usebenzisa ezinye adrenoblokatorovv alpha-1A okanye womchamo kunye iintlungu. anefuthe elivakalayo kinetics amayeza zamaqhezu ezamahala "Diazepam" yaye "chlormadinone" yi ukulungiselela "Tamsulosin" yemiyalezo (ixabiso ngasentla kuthetha -. 500-1400 miri) ayichazwanga.

iimeko Ukugcinwa ezikhabhathini

On iimeko yokugcina beziyobisi "Tamsulosin" sikhokelo ucacisa oku kulandelayo:

• ekhuselekileyo uluhlu lobushushu - 15-25 degrees Celsius;
• ukufuma elilelona - 70%.

Nkalo zokufunda yokugcina kwi bezifakwe kuyo (endaweni engafikelelekiyo kubantwana, nto leyo ekhuselwe kakuhle elangeni ngqo).

Xa zonke iingongoma imiyalelo ziziqinisekiso kumenzi umphumo enyangayo "Tamsulosin" akuyi buthathaka kwiminyaka emibini ukususela ukukhululwa yayo.

Drug analogue "Tamsulosin"

Uluhlu "kabini" imelwe ngamaqela amabini iziyobisi. Iqela lokuqala luquka iziyobisi, eqhelekileyo, owesibini - lwamagama trade esinqabileyo.

imali Public:

• "Omnic" (kweyoqobo - Omnic), umvelisi - eNetherlands, ifomu ukukhululwa - tablets / njengezingxobo iziqwenga 10/30 pack nganye, ixabiso kuluhlu - 380-1700 engange.
• "Proflosin" (Proflosin), eJamani, namadyungudyungu iipilisi 30, iindleko eziqikelelwayo - 500 engange.
• "Sonizin" (Sonizin), iLizwe lemveli - Romania, impahla esemgangathweni njengezingxobo-10 okanye 30, ixabiso avareji - 450 engange.

zokuthengisa amagama orhwebo ichiza "Tamsulosin" Ezinye (analogs ukuba azixhaphakanga okanye ukukhulula sele iifom ndiyayithabatha zemveliso):

• "Omsulozin" (Omsulosin), India, njengezingxobo 0.4 mg (30 iiPC.) Amanzi Ixabiso ukusuka 350 ukuya 550 engange.
• "Tamsulosin-Teva" (Tamsulosin-TEVA): "UTamare-Actavis" imveliso inkampani, Greece, imilo nokupakishwa ixabiso kuyafana kwimeko yangaphambili.
• "Tamsulosin-kunamandla" ( "understudy" component release ezinzileyo), umgca yemveliso kuhlala eRashiya, amacwecwe 400 mg, iindleko - malunga 300-360 engange.

"Tamsulosin": Ukubuyekezwa koogqirha kunye nezigulane

unyango Medical nalo eli chiza yimpumelelo ngokubanzi kwaye ingavezwa mazwi Isemantiki lokuba yamathumba prostate non-amabi.

Emva 90 iintsuku iimpawu ziye zancitshiswa ngo-2 amaxesha, kunye utshintsho zokuqala buqapheleke sele ambona iintsuku 14-21. Emva kokugqitywa iimpawu uwela isalathisi nge-75% (xa kuthelekiswa ne kwisigaba eqala), nto leyo ngokuqinisekileyo njengabaneziphumo eyamkelekileyo.

Beautiful tolerability "Tamsulosin" (ixabiso sikhokelo kunye machiza zixhaphakileyo generic zinikwa ngasentla) kwenza kube lula kakhulu ukuba ukusebenzisa xa ukhupha izigulane kunyango. Noko ke, ukuze kuzuzwe lukhulu naliphi ukwimo asanelanga, kucetyiswa ukuba uthomalaliso ngaxeshanye kunye nezinye iindlela kunye neemveliso amayeza.