Ichiza "metipred" izinto azimiselweyo? "Metipred": zikhombisa ukuba ukusetyenziswa

Ezinye izifo kunokwenzeka kunye ukumelana ethile ngamachiza, t. E. Musa ukuphendula nolawulo iziyobisi. Kwiimeko ezinjalo, njengokuba umthetho, ukuba babhenele ukusetyenziswa glucocorticoids. Omnye ichiza "metipred". Yintoni emiselweyo iyeza yaye unjani?

Yintoni na eli chiza?

"Metipred" libhekisela kwiqela glucocorticosteroids zokwenziwa, t. E. Ngaba zamntu kuhlelwe hormone analog. It has umsebenzi anti-ukudumba, ukuba isiphumo anti-kukwalisa, kunciphisa nokudumba, lihlisa umsebenzi kwinkqubo eziliqela omzimba, azimise ukuphazamiseka yokucolwa.

indlela yayo yokusebenza isekelwe zasabela receptors ezithile akhiwe izicwili ezininzi. Ngokunxulumanisa baqale iiproteni eyodwa zinoxanduva lokulawula iinkqubo ibaluleke kakhulu.

Eli chiza nefuthe zonke iintlobo iinkqubo pathways emzimbeni.

Ekubeni kweziyobisi bobabo iqela glucocorticoids, oko kumiselwe kuphela kwiimeko ezithile, xa isiseko kuthetha eboniswe ukuba unyango lwesi sifo kuba alusebenzi.

Kwezinye iimeko, ke, ungasebenzisa "metipred"? Kutheni uyakukumisela lona eli okanye sifo?

Ubungqina obubonakalayo buxela ukuba

Ziziphi izifo ifuna ukonyulwa kwabo unyango lwamachiza hormone? Ukuba kukho naziphi na izigulo lubonisa "metipred"? Yintoni na le imithi?

Ukuqeshwa lokuqala ichiza kuyimfuneko izifo zenkqubo kwizicwili. Ngenxa yoko, ukuba ngaba: scleroderma systemic, systemic lupus zomzimba, vasculitis bonke, dermatomyositis. Kule meko, hormone inceda ukwehlisa nangokurhala, buyisela sokufudumeza emzimbeni abachaphazelekayo.

Zamathambo kwakhona ngokubanzi "metipred". Iimpawu - izifo kwingxakeko yokukrala amalungu: samathambo, umyalezo samathambo kunye psoriatic, osteoarthritis, bursitis, synovitis, ankylosing spondylitis. Isiphumo ephambili beziyobisi kwezi zifo - anti-ukudumba kunye iintlungu.

Kuyenzeka ukuba usebenzise 'metipred "somoya inyumoniya kunye iintlobo zezifo ezingapheliyo komzimba.

uhlengahlengiso balawule

Koko imithamo ibonisa ukusetyenziswa 'metipred'? Kufuneka kukhunjulwe ukuba ukuqeshwa ichiza, kwakunye nezinye iihomoni, kuyimfuneko ukuba uyithathele ingqalelo ezi izingqisho lomzimba na emzimbeni, kwakunye umsebenzi uthinte adrenal. Ithamo ukuba isigulane ngasinye esikhethwe ngamnye.

Isixa ngemihla hormone kungcono kuthathwa kusasa (idla bayacetyiswa ukuba basele lonke ithamo kuluhlu ukusuka kwisi-6 ukuya kwisi-8 nentsimbi kusasa, okanye ukuba alabe libe izigaba ezibini - ngamaxesha-8 no-12). Umthamo waphawula kuzo zonke amalungiselelo hormone. Ngaba Akukho ngaphandle kunye "metipred".

Iipilisi zithathwe ngqo ngexesha isidlo okanye emva kwayo. Ebantwaneni, ithamo uzimisele ngokungqinelana nobudala kunye nomzimba weight.

ukulungiselela oqhelekileyo uvela mg-4 ukuya ku-50 ngosuku. A yedosi ephezulu (1 g) kuboniswe kwizigulane kunye systemic nokuqina izifo zeethishu ubungqongo obukhulu. ingqalelo ekhethekileyo kufuneka inikwe ukuqeshwa ichiza kwisiqu esinye kumamkeli, okanye in vitro.

imiphumela emibi

Nge umthamo eyiyo ichiza kunye nokugcina imiyalelo zonke kagqirha xa uthatha iziphumo ebezingalindelekanga zenziwa phantse nesimo. Nangona kunjalo, kufuneka kukhunjulwe ukuba xa zokugxojwa kweemeko yolwamkelo ukuze aphuhlise imeko kakhulu ngokwaneleyo. Oko kunokubangela ngokusetyenziswa eli yeza?

"Metipred" ngokuyintloko kuba nefuthe elibi kwinkqubo yonyango. Ngamana zifumana ukuhla ukunyamezelana iswekile, uphuhliso syndrome ka Cushing, uphuhliso ukulibaziseka ngokwesondo (xa wabela abantwana).

Le nkqubo yokusila unako ukuphendula nolawulo lophuhliso zeziyobisi of isicaphucaphu nokugabha, utshintsho ilindle, i-pancreatitis, isilonda, kude kulawuleke ukopha kunye perforation eludongeni isisu.

Isiphumo "metipred" kwinkqubo yegazi lubonakala njengoko arrhythmia, bradycardia, ukonakala kweendlela eziphilayo xa ukusilela entliziyweni.

I-luvo sivame deliriepodobnoe nemeko yophuhliso ukugula ngengqondo, clinical, efuna vertigo.

Izimo

Xa kufuneka usebenzise eli yeza? "Metipred" zingasetyenziswa kuphela ukuba ixesha analo lifutshane. Ngokufumana elide Izimo uluhlu enkulu kakhulu.

Amanyathelo asetyenziswa amachiza izifo wokugaya ezifana nezilonda, gastritis, sisilonda sikabhobhosi, uqhaqho zesisu.

Izifo ezininzi ezosulelayo nazo zifakwe kuluhlu Izimo isizalwane, ekubeni ayaziwa ngayo umzimba asabela nokulawulwa hormone iziyobisi. Enye imeko yokuba ukusetyenziswa kwe hormone na isiphumo yabo immunosuppressive.

Musa ukusebenzisa iziyobisi ngenxa seswekile, ukutyeba.

Abantwana kunye nabasetyhini abakhulelweyo ukuba ubalwa Izimo ngokupheleleyo ekusetyenzisweni "metipred". Yabela oko kwenzeka kuphela kwimeko apho kukho isoyikiso elibalulekileyo ebomini.

Unxibelelwano namanye amachiza

Yinto eyaziwayo ukuba amachiza amaninzi nezinokuphucula, ukunciphisa okanye yokungenelela ifuthe amanye amayeza. Iba "metipred" Indlela nolawulo esihamba kunye nezinye iziyobisi?

Ukusebenzisa le amayeza kunye inducers transcriptase hepatic kunciphisa uyondelelwano lwee- into esebenzayo egazini (inyusa yokucolwa wayo).

Ukuba amayeza kwenkcazo 'metipred "kunye womchamo kuphula ubungozi sisifo sentliziyo kunye hypokalemia.

"Metipred" unyango ukubetha, ngelixa ukuqeshwa glycosides senhliziyo umyalelo kwandisa umngcipheko ventricular arrhythmia.

Musa ukuyisebenzisa ne methylprednisolone kunye anti-coagulants, njengoko zisiba isiphumo konwaywa wamva.

Ukuthatha ichiza notywala kunye arhente nonsteroidal kwandisa umngcipheko izilonda emathunjini.

"Metipred" kunciphisa ukwanela insulin kunye neziyobisi umfutho.

Imiyalelo yokusebenzisa

Ziziphi iindlela idosi khona unako 'metipred "? Kutheni yabelwa ngamnye kubo? Makhe sijonge le miba ngokweenkcukacha ezingakumbi.

"Metipred" (tablets) neefom ezimiselweyo kwezifo wobulali nayo xa engekho Izimo ngenxa yokufakwa.

Lyophilisate - uhlobo eyodwa ichiza, nto leyo olungumgubo ukuxutywa kunye nolawulo efakwa. Xa zisetyenziswa kakhulu kwiintlobo kakhulu sisifo, ngokunjalo uncedo olungxamisekileyo.

Isisombululo engumphumela ekucetyiswa ukuba mayisetyenziswe ngoko nangoko. Ukuba bafuna ukugcina okwethutyana, ngoko ke kufuneka kwenziwe kwiqondo lobushushu degrees-15 ukuya kuma-20. Ngamaxabiso asezantsi ayikwazi ukugcina ichiza iphekwe ngaphezu kweentsuku.

Kuba ukhuseleko isigulane Kucetyiswa ukuba usebenzise asidi ngaxeshanye (ukukhusela isifo).

Phambi ukusetyenziswa, ichiza kufuneka kusoloko ubonane nogqirha malunga idosi rhoqo imicimbi yayo.

"Metipred" kwi unyango ukungachumi

Xa izifo nococeko, ngokunjalo namanye amacandelo amayeza, ungasebenzisa "metipred". Yintoni na le amayeza emiselweyo?

Eyona Ukusetyenziswa kweziyobisi - omzimba neqanda.

ECO - inkqubo, eli eliza kunika iqanda umfazi, eye ngendlela ityhubhu yovavanyo oyindoda sperm kunye nokuphunyezwa elilodwa neziphumo esibelekweni.

"Metipred" IVF iboniswe ezinye omzimba. Kucetyiswa ukuba basebenzise iintsuku ezimbalwa emva kokukhutshelwa elilodwa kuloo ndawo ibinomthwebeba zesibeleko. Oku kwenziwa ukuze kupheliswe ukufunyanwa kwaliwa umzimba, "into langaphandle".

Xa ayaphumelela kwenzeka umbungu umzila kwi endometrium, ukusekwa ngumkhaya kunye nokukhula ezingekazalwa bemveku.

"Metipred" IVF liboniswa bonke abasetyhini. Phambi Izimo ukuba ukusetyenziswa kwayo kufuneka kushiywa neqanda.

Ezinye izifo kwenkqubo ababhinqileyo lokuzala angafuna ukuqeshwa hormone. "Metipred" kwi zuza wambi kusetyenziswa ukunyanga leukoplakia kunye neenkqubo ezithile arhabaxa.

Unyango lwezifo lwenkqubo

Phantsi kwezi meko, ngokuqhelekileyo kubhenela ebizwa ngokuba unyango ukubetha. Undoqo yale ndlela unyango ngolu hlobo lulandelayo: elo xesha lifutshane ixesha (ngokuqhelekileyo 1-2 iintsuku) isigulane ilawulwa idosi enkulu kangangoko, andule ukunyusa ngenxa iiveki eziliqela (ngokuxhomekeke ubungozi uhlobo lwesifo) - yedosi yokugcina amayeza.

Ngokomzekelo, xa unyango lwe vasculitis lwenkqubo, eli cebo na ngolu hlobo lulandelayo: ukulungiswa "metipred" kuqala yayisalawulwa umthamo we ukuya ku-1000 mg, ngoko ke isigulane idluliselwa unyango noncedo (80-100 mg).

Esi sikimu yasetyenziswa ngenxa kakuhle yalo phezulu.

Ukuqaliswa amathamo ezinkulu ikhuthaza "uxinezeleko" sesi sifo kunye nophuhliso ngokumka ekuthiwa-metabolic. Kulo mzekelo, umzimba ochaphazelekayo lula ukubuyisela reactions yesiqhelo ngaphezu kwabo ngaphandle ifuthe aqatha kangaka. Kwakhona, ngenxa ngokwemithamo enkulu kunokwenzeka ukuba zinqanda uninzi omzimba.

therapy Pulse unako kumana kunye cytostatics ukuphumeza isiphumo ngokukhawuleza kakhulu immunosuppressive.

Ukubaluleka ngokusebenzisa ichiza

Olu nyango ayikwazi uthenga kwi ivenkile. ugqirha kuphela ukunika amayeza "metipred". Iimpawu kufuneka zinzima (umz, izifo systemic arhabaxa). Kuphela kulo mzekelo, ayinikiwe uya kuninika amayeza kuyimfuneko.

Enye inkalo beziyobisi kukuba xa ukusetyenziswa nelide sesona likhoboka kunokwenzeka okanye imbonakalo iimpawu ukurhoxiswa.

Yenzeka kwimeko apho ixesha elide kwaye ngokwemithamo eziphakamileyo lusekelwe "metipred". Ngaxeshanye, kukho uxinzelelo iihomoni zakhe eveliswe adrenal. Kulo mzekelo kufuneka ngoko nangoko abrogate iziyobisi. Kucetyiswa ukuba ixesha elide ukunciphisa ngokuthe ithamo. Kuphela phantsi kweemeko ezinjalo eziqhelekileyo hormone amagama kubuyiselwe.