Ukulungiselela "Aleron": imiyalelo yokusetyenziswa, inkcazo, imizobo

Ziziphi iipilisi ze "Aleron"? Imiyalelo yokusetyenziswa, izibonakaliso zokuthatha eli nyanga ziya kuchazwa kamva. Kwakhona kwinqaku uza kufunda malunga nokuba kunokwenzeka yinike ukunika izibisi kubantwana, nokuba ngaba kunokuchasene, nokuba ngaba kubangelwa yimiphumo emibi, njl njl.

Inkcazo, ukubunjwa kunye nokupakishwa

Ziziphi iindidi ezithi i-"Aleron" imithi? Umyalelo, inkcazo yokulungiselela, ichazwa ukuba into esebenzayo yi-levocetirizine dihydrochloride. Kwimeko yokwakhiwa kwamachiza kuncedisa i-lactose monohydrates, isitashi samabele, i-magnesium stearate, isitashidi ye-sodium glycolate (uhlobo A), i-colloidal dioxide kunye ne-microcrystalline cellulose.

Ngowuphi uhlobo lokupakisha ndingayithenga u-Aleron? Uqeqesho leliyeza lifakwe kwibhokisi yekhadibhodi. Iqulethe i-blister eneepilisi ezimhlophe kunye ezijikelezayo kwiigolke zefilimu.

Izinto ze Pharmacological

Ziziphi iimpawu zithi i-"Aleron" ineyeza? Imiyalelo yokusetyenziswa ikwazisa ukuba i-antiallergic agent. Uthunyelwa kwiqela lama-antihistamines kwisizukulwana sesithathu.

Icandelo elisebenzayo leziyobisi liyakwazi ukubonelela nge-anti-inflammatory, antipruritic, i-antiexudative kunye ne-anti-effects effect. Kwakhona, eli liyeza linemiphumo echazwe ngokuthi i-antihistamine.

Umgaqo wokusebenza

Isilwanyana "Aleron" sisebenza njani? Umyalelo uthi i-levocetirizine inokuthi ivimbele i-H1-histamine receptors, kunye nokuthintela ukukhululwa kwe-histamine ngenxa yokuzinzisa kweembrane zesitampu.

Ngokweengxelo zeengcali, i-M-cholinergic kunye ne-serotonin receptors ayinayo nayiphi na impembelelo kumachiza onombuzo.

Ukufezekisa impembelelo yokwelapha, isixa se-levocetirizine sidinga isiqingatha se-cetirizine. Oku kubangelwa ukuba iqela lokuqala lenza ulwalamano olugqithisileyo kunye nabamkeli.

Emva kokuthatha le nkunkuma, ukuveliswa kwemichiokines kunciphisa. Kwakhona, i-chemotaxis ibinqatshelwe, ukubunjwa kwama-cytokines anesibindi, ukunciphisa i-eosinophil kunye nokubonakaliswa kwee-molecule ziyancipha.

Ngaphantsi kwefuthe lonyango, ukukhululwa kwe-histamine exhomekeke kwi-IgE, i-leukotriene C4 kunye ne-prostaglandin D2 iyancipha. Ukongezelela, isilwanyana sinomphumo ogxininisayo kwinto yokukhupha i-thrombocytotivating factor of the skin.

Iipropati zemveliso yeyeza

Ziziphi iipropati ezihambelana nesilwanyana "Aleron"? Umyalelo uthi le ngonyango ikhuthaza kakhulu ubunzima beempawu zeendlela ezahlukeneyo zokuzilahla (umzekelo, i-rhinitis ye-allergen).

Izigulane ezihlala zihlupheke kwiimeko zonyaka zingasebenzisa ngokukhuselekileyo le mpendulo ukuphucula impilo yabo, kunye nokukhusela ukubonakala kweempawu ezingathandekiyo.

Ngokutsho kweengcaphephe zengxelo, iyeza elisezantsi lombuzo libonakaliswe ngokufanelekileyo kwi-asthma ne- cold urticaria. Ngelo xesha, inxalenye yayo esebenzayo ayinayo ingozi enobungozi entliziyweni, kwaye ayivimbeli inkqubo yentshontsho enkulu.

Pharmacokinetic parameters

Ngaba kunokwenzeka ukuthatha i-Aleron ngexesha elifanayo njengokutya? Umyalelo uthi ukutya akunampembelelo ekubanjweni kweliyeza (kwinqanaba elithile linganciphisa izinga lokumathisa).

Isilwanyana sithatyathwa ngokukhawuleza kwindlela yokugaya. Inqanaba lalo lokuhlaziywa yi-100%. Uxinzelelo oluphezulu lwezinto eziphambili kwigazi liphawulwe emva kwemizuzu engama-50-60. Iiprotheni ze-plasma, isizabisi sibophelela kwi-90%.

Inxalenye encinane yesilwanyana ixiliswe kwisibindi. Ngenxa yoko, i-metabolite engasebenzi. Isiqingatha-sobomi se "Aleron" si-9-10 iiyure. Kwiintsuku ezine, kupheliswe ngokupheleleyo emzimbeni ngamazinyo namathumbu.

Iimpawu zokusetyenziswa

Iyintoni ukusebenzisa kweyeza "Aleron" (iipilisi)? Umyalelo uyazisa ukuba le nkunkuma imiselwe ngenjongo yokonyango kunye nokukhusela ukubonakaliswa kwezinto ezibonakalayo, ezinokuthi zibe zibini kwaye zingapheliyo.

Ngoko, le nkunkuma ingasetyenziselwa izifo ezifana nale:

• Urticaria;
• I-rhinitis ye-allergen;
• I fevayi;
• Angioedema ;
• I-dermatoses ye-allergen, ehambelana nomvakalelo wokutshisa, ukutshisa, kunye neengqungquthela kwiimbumba ezinobumba kunye nesikhumba;
• Conjunctivitis.

Ukungqinelana kokusetyenziswa

Ziziphi iingqinisiso kwiyeza "Aleron"? Imiyalelo yokusetyenziswa (kubantwana banokuthintela) ikwazisa ukuba akukho mfuneko ukuba lo mveliso unikwe umntwana ongaphantsi kweminyaka emithandathu. Kwakhona, isilwanyana asivumelekanga ukuba silawulwe phantsi kwezi meko zilandelayo:

• Ukuhluleka kwe-Renal, kwenzeka kwifom enzima;
• Umgangatho ophezulu wobubele besigulane kwiinkalo ezichaphazelekayo ze-arhente, kwakunye nakwimveliso ye-piperazine;
• Ukuxutywa kwe-glucose kunye ne-galactose;
• Ukungathembeki kwi-galactose.

Ukulungiselela "Aleron": imiyalelo yokusetyenziswa

Thatha amacwecwe e-Aleron kufuneka athathwe kuphela ngokwemiqondiso. Ziyalelwe izigulane zabantu abadala, kunye nabantwana abaneminyaka emithandathu ubudala.

Isilwanyana sithathwa ngomlomo ngokuhlamba kunye neelwelo eziqhelekileyo. Ubude bexesha loqeqesho, kunye nokulingana kwamachiza kunikwa kuphela ugqirha, kuxhomekeke kwisifo.

Ngokuqhelekileyo, i-antiallergic agent "Alerone" imiselwe enye ipilisi enye ngosuku. Umthamo wansuku zonke walesi sidakamizwa akufanele udlule 10 g.

Ngokwemiyalelo eqhotyoshelweyo, ngoqhagamshelwano olufutshane kunye ne-allergen, unyango ngale nkunkuma kufuneka luqhutywe ngeveki. Ukuba isigulane sibhekene nesifo sefiva, inkqubo yokonyango inokuhlala ifike kwiinyanga enye kunye nesiqingatha. Ukuba kuyadingeka ngokukhawuleza, unyango luyongezelwa kwiinyanga ezintandathu.

Ngokufanayo, isilwanyana "u-Aleron Neo" kufuneka sithathwe.

Umyalelo oqhotyoshelwe kwicawa ukwazisa ukuba abantu abanokuxilongwa ngokungafezeki kwenkunkuma kufuneka bahlonyelwe i-dosage. Xa isibindi sisiphazamisekile, irejimen efanayo ye-dosing isetyenziswe njengabantu abaqhelekileyo.

Izimpembelelo ezimbi

Ziziphi iziphumo zecala leziyobisi "Aleron"? Imiyalelo (kubantwana kunye nabantu abadala) ibikela ukuba eli galelo linokubangela ukubonakala kwezi ziphumo ezilandelayo:

• Uvakalelo lweentlungu ezinamandla;
• I-hepatitis;
• Ukukhathala okukhulu, intloko, ukunyamezela, ukulala, ukuxhalaba, ubuthathaka, ukuxinwa;
• Umbono onzima;
• Umlomo ococekileyo kunye nesiphithiphithi;
• I-Edema kunye ne-anaphylaxis;
• Ukuphefumula;
• Intlungu yesisu, i-myalgia kunye nokufumana ubunzima;
• Urticaria, ukukhumba isikhumba kunye nokukhawuleza.

Iimpawu zokugqithisa

Xa uthatha amanyathelo aphezulu eziyobisi kwizigulane ezimakwe ngxininiso obukhulu okanye, ngokuchaseneyo, imeko yokugxininisa, ilandelwa ukulala. Xa ubona iimpawu ezinjalo, isilwanyana kufuneka silahlwe. Isigulane sifanele sibekiwe ukuba sihlambe isisu, kwaye simnike i-enterosorbent.

Ukusebenzisana kwezidakamizwa

Ngokulawulwa ngokufanayo kwe-levocetirizine kunye neziyobisi ezinokuthi i-metabolism ihambelana ngqo neenkqubo ze-cytochrome P 450, akukho nziswano. Nangona kunjalo, ngokufakwa ngokuphindaphindiweyo kwe-theophylline, ukukhutshwa kwe-levocetirizine kuncitshiswa kwinqanaba elithile.

Akukhuthazwa ukudibanisa iyeza "u-Aleron" kunye nezidalwa.

I-Levocetirizine ayichaphazeli ukungena kwe-ethanol.

Iingcebiso ezizodwa

Ngokwemiyalelo, le nyanga imiselwe ngokunyamekela abantu abakhulileyo, kunye nalabo abanesifo sengqondo.

Ngexesha lokumkela i-antiallergic agent "Aleron" isigulane akacebisi ukuba aqhube kunye nokusebenzisana neendlela ezinzima.

Ukukhulelwa kunye ne-lactemia

Ulwazi malunga nokusetyenziswa kweziyobisi "u-Aleron" ekukhulelweni akulona. Ngoko ke, ngexesha elichaziweyo, kufuneka liqeshwe ngokuqaphela okukhulu.

I-Levocetirizine ingena kubisi lonina. Kule nkalo, ngexesha lokusetyenziswa kwalo, kubalulekile ukuyeka ukuncelisa.

Iintetho kunye nexabiso

Kukho izidakamizwa ezininzi ezinokuthi zitshintshe izilwanyana "Aleron". Amayeza anje afaka oku okulandelayo: "Aleron Neo", "Glenceth", "Alerzin", "Xizal", "Cesera", "Tsetril" njalo njalo.

La machiza anefuthe elifanayo. Nangona kunjalo, kufuneka isetyenziswe kuphela ngenjongo yeengcali.

Ngokumalunga neendleko, iyeza elikulo mbuzo aliphezulu kakhulu. Ungathenga amacwecwe "u-Aleron" ngama-ruble angama-220-240.

Iingxelo malunga neziyobisi ezichasayo

Isilwanyana "i-Alerone" asithandwa kakhulu. Ngoko ke, ukuphononongwa ngaye ngaye kunqabile kakhulu. Kuzo ezikhoyo, sinokugqiba ngokugqibeleni ukuba le nyilisi iyakwazi ukujamelana nalo msebenzi. Ukutya okungaqhelekanga kwamacwecwe kukuvumela ukuba ususe ngokukhawuleza nangempumelelo zonke iimpawu ezinxulumene neentlungu. Ukulungiswa kunceda lula imeko yezigulane, kwaye kukuthintela ukuvela kweempendulo ezingathandekiyo.

Phakathi kweengcamango ezingathandekiyo, kukho rhoqo ekuthethwa ngazo ukuba izidakamizwa ezibhekiselweyo zihlala zibangele iziphumo ezibi.