Prostaglandin - it ... Prostaglandins (ARVs): Ixabiso igama

Uninzi iinkqubo emzimbeni wethu ixhomekeke prostaglandins, leyo ziveliswa phantse zonke izicwili. Ngokufuthi babonwa iihomoni, Noko ke, kungenjalo. Benza preferentially kwisiza kuyondelelaniswe uze phantsi kwintshabalalo. Le hormone sizibhokoxe impembelelo emgama ahluka kuphela kwamadlala ezidalwe nezihlunu azikho kuba becala.

i Yindibanisela prostaglandins

Makhe sijonge ukuyilwa weli emzimbeni. Prostaglandin - into lasekwa ngo nethe lwe CD acid, ukuba Eicosanoids. fatty ziyinxalenye phospholipids, apho zifumaneka zonke izicwili. Phantsi yesenzo phospholipase A2 ibola CD acid, emva koko liphuma kwi cyclooxygenase okanye lipoxygenase ezijikelezayo. Prostaglandins na imveliso lokuqala.

Yintoni indima emzimbeni?

Eicosanoids ukwenza ezahlukeneyo kwemisebenzi. Prostaglandin - into leyo bathathe inxaxheba ezininzi iinkqubo olwenzeka emzimbeni wethu. Hi xikombiso, le prostaglandin E kuba depressor ukusebenza, ngamanye kunciphisa uxinzelelo igazi echaphazela ilizwi nemithambo. Ukongeza, prostaglandins (iziyobisi kunye zendalo) ukuqalisa umsebenzi contractile le myometrium, ngenxa leyo apho asetyenziselwa kuFacebook yabasebenzi. Ezi izinto landise kuyondelelaniswe yencindi yenziweyo iiseli wayifinca esiswini. Yencindi ezisebenza umsebenzi ezikhuselayo, nokuthintela isenzo yeemeko ndlongondlongo kwi isifo. Ukongeza, ngenxa ezi izinto into zicinezelwa ukubunjwa pepsin kunye zehydrochloric acid, nto leyo esetyenziswa ngempumelelo unyango lwezifo esiswini ezinxulumene secretion nangakumbi ezi izinto. Kananjalo kuchaphazela iimpawu rheological igazi, ziyibuyisela zegazi udibaniso. Prostaglandin E kuchaphazela iiseli umsipha kakuhle uqhoqhoqho kunye bronchi, lukhuthaza ukuphumla zabo, yaye ngaloo ndlela, ukwandiswa yomoya. Indima ebalulekileyo prostaglandins e nokudumba kunye neentlungu. Ezi zinto zingakuchaphazeli ngqo kwalapho kunye zomzimba, kodwa bazibandakanye inkangeleko ezinye iimpawu komtshiso oko. Utshintsho kwi isandi nemithambo phantsi intshukumo ye prostaglandins ezikhokelela kwingxinano, kunye nokwanda permeability kodonga - unobangela ekumisweni nokudumba. Prostaglandins, ukongeza ifuthe ukuba on the luvo vagus, ibangela isicaphucaphu nokugabha. Elingaphambili abe neziphumo ezinje icala a rhoqo ziyenzeka izigulane. Prostaglandins - amachiza (amagama ngezantsi) asebenza kuphela phantsi ezibonisa engqongqo.

Intsebenziswano ye prostaglandins kunye neziyobisi anti-ukudumba

Prostaglandin - yinto nxaxheba ngqo kwinkqubo arhabaxa. Intshukumo ka NSAIDs isekelwe phezu ukuncitshiswa kuyondelelaniswe (cyclooxygenase enzyme iyabhlokwa). ukusetyenziswa zexesha elide NSAIDs kukhokelela nokunqongophala prostaglandins, neziphumo umsebenzi umqobo kakuhle esiswini - ukuhla secretion yencindi yomlomo. Oku kubangelwa enkulu kula machiza.

Prostaglandins - amalungiselelo: igama

La machiza asetyenziswa ngokuyintloko izifo nesisu kunye isilonda duodenum, uhlobo ilunga. Ukongeza, ukuba zilawulwa ukuvuselela yindibanisela le myometrium nokuphucula rheology negazi.

"Misoprostol"

Prostaglandins (ARVs) ezisasazwa kwi unyango izilonda esiswini kunye duodenal ngenxa umsebenzi wayo anti-secretory. Eli nyathelo lu dityanisiwe nefuthe receptors prostaglandin, apho ibekwe iiseli Parietal esiswini. Ngaloo ndlela, "Misoprostol" izenzo njenge prostaglandin yendalo. Ingqondo yemveliso yencindi inceda ukukhusela inwebu yangaphakathi kwaye uthintele ukuyilwa izilonda ezintsha. Konke oku kudala iimeko zivuma ukuphilisa izilonda kunye erosions.

"Alprostadil"

Iyeza le prostaglandin ichiza E. Oku esuke kwiimeko apho ukwanda ezifunekayo kunciphiso myometrium - kuFacebook yabasebenzi. Kwakhona, ichiza isetyenziselwa ukuphucula kwegazi - inhibition of zegazi udibaniso kunye vasodilation (yamafutha). Kuyinto ifumaneka ezineengqayi lolawulo efakwa.

Izimo

Zombini ichiza na ilawulwa, ukuba kukho hypersensitivity ukuya prostaglandins kunye analogs zayo. Phakathi Izimo - eyi-18, ukukhulelwa kunye nokuncancisa. Kwakhona thatha isilumkiso zabo izigulane insufficiency kwezintso kunye hepatic, ezimbi kwinkqubo yonyango, enterocolitis, igazi.

Self-ulawulo prostaglandin iziyobisi ngaphandle kokubonisana ingcali ayivumelekanga. Kuphela ugqirha ukufumana idosi ekunene kwaye ulungise isicwangciso sonyango, kuthathelwa ingqalelo iimpawu ngamnye yesigulana. Kuxhomekeka locale wakho ukutshintsha ixabiso. Prostaglandin ifumaneka kwiintlobo ezahlukeneyo phantsi ezahlukeneyo amagama lophawu, oko kuchaphazela iindleko.

imiphumela emibi

Amaninzi, xa iziyobisi kukhokelela ezingaqhelekanga kwinkqubo yokwetyisa - isicaphucaphu, ukugabha, urhudo kunye nezigulo dyspeptic. Ukuba umzimba, ephawulwe pruritus, irhashalala, ububomvu kunye ukudumba, kwaye kunokwenzeka ukusabela anaphylactic. Ulawulo iziyobisi ukuze ezinxulumene esexesheni mgaqweni, seTrojan. Ukunciphisa myometrium oko kudla luphawulwa iintlungu esiswini. Phakathi kwezinye ziziphumo ebezingalindelekanga - isiyezi, intloko ebuhlungu, ukwehla kobunzima bomzimba.

Izinga lokuba nemiphumela icala ngamnye ukuba isigulane ngasinye. Xa sigcina izenzakalo ezinjalo kufuneka uqhagamshelane nogqirha wakho uze utshintshe isicwangciso sonyango.

Prostaglandin - into efunekayo xa unyango lwesifo isilonda Peptic kunye nezinye izinto ezimbi. Zidla zidityaniswe namanye amachiza ukuze kuphunyezwe neziphumo ebezifuneka. Ukhetho amayeza kwaye umthamo walo kuxhomekeka kwimeko lwezonyango kunye neempawu isiguli ngasinye.