Inhibitors Aromatase: ncomo, amaxabiso. inhibitors Aromatase in abanxibe impahla

inhibitors Aromatase, okanye blocker, - uhlobo ephilisa izixhobo ezisetyenziswa ukunciphisa uyondelelwano lwee- estrogen egazini nokunyusa umgangatho gonadotropins kunye testosterone. Ezi zinto ke iphinde isetyenziselwe iinjongo unyango kunye nothintelo gynecomastia eyindoda.

inhibitors Aromatase e abanxibe impahla adla ngokusetyenziswa ngethuba lokuqhubeka konyaka u-steroid steroid ku:

• ukuphucula intsebenzo hormone steroid egazini;
• Uthintelo gynecomastia;
• ukunqanda wegazi;
• ukwandisa esigingqini (ngokususa nefuthe elibi estrogen);
• ekunciphiseni estrogen intshabalalo axis amasende-yebhinqa-yobuchopho, nto leyo ekhokelela ukuba ngokutsha ngokukhawuleza.

Ukwakha izifundo, kufuneka ukubalelana nesibakala sokuba incasa abawuthobeli zonke steroid. Sebenzisa bugwetyelwe xa ukusetyenziswa iimveliso ezifana methandrostenolone, methyltestosterone, testosterone kunye nezakhi zayo. Kancinane eliphekwe Halotestin, boldenone.

ukusebenza

Le inhibitors aromatase kakhulu ikhethekayo ekhoyo (for echumayo phantse efanayo):

Kufuneka kuqatshelwe ukuba xi ngokulinganisela estrogen iluncedo ekukhuleni imisipha, iidosi kunjalo olukhuselayo kubonisiwe izixa echaphazela ekulondolozeni inqanaba physiologically efunekayo estrogen eyindoda.

Ukusebenzisa indlela

Uninzi leembaleki zasekhaya usebenzisa aromatase inhibitors, sebenzisa maqhinga alandelayo: machiza asetyenziswa kuphela xa Iimpawu zokuqala gynecomastia (ukurhawuzelela le neengono zithi, ukudumba, ububomvu). Ngelishwa, le ndlela ngeke ngokuba kangangoko.

Isisombululo kakhulu ifana kucingwa ukuba kuvavanywa estradiol malunga ezilishumi iintsuku, ukusetyenziswa steroid kunye elifutshane isiqingatha-ubomi ( "Methandrostenolone", "testosterone propionate") okanye iiveki ezintathu okanye ezine ukusetyenziswa Ester evuthelweyo ( "Sustanon", "enanthate," "cypionate"). Ngaphezu koko emiselweyo avareji isahlulo "Anastrozole" - 0.5 mg yonke eminye imihla. Emva kweentsuku ezilishumi, wenza uhlalutyo ukulawula estradiol kunye idosi yoxhaso kwiziphumo.

Ukuvumelana ukusebenzisa servings eliphantsi kunye neliphakathi "Anastrozole" swi umbono zobuqu. Ukuba emva uba edandathekileyo olo nyango, ukuphazamiseka umsebenzi erectile, yobuntu drop, ngoko ke kufuneka ukunciphisa idosi.

uphando

Ukuvela lophawu "letrazole" kawonke bazisa le mveliso kwi akhokele. Kukho iindidi zovavanyo ukungqina impumelelo ephezulu kwesi sixhobo emadodeni. Ukwaziswa kwezinto kunye ukunyuka wokuthi gonadotropin (LH). oyidlayo elinemveliso ivela 0,02 mg (kwezonyango ngezantsi amaxesha 100): ukuba kunokwenzeka kusetyenziswa estrogen ingqalelo esezantsi wesithathu. 50% "letrozole" bungaveli emzimbeni kwiintsuku 2-4, akwazi ukuba asele ngosuku. Le ethile esisiseko ithathwa ukukwazi kwayo kumanqanaba asezantsi estrogen, nkqu ngeedosi ezincinane.

"Anastrozole" ithandwa abanxibe impahla, yakhe emihle wafunda abantu njengendlela yokunciphisa estradiol. Empirically bekubonakalisiwe ukuba ithamo zenqanaba estradiol 1-0.5 mg ukuze sehle nama-50%. Abathengisi Le mveliso zingathengwa ukuya kalishumi zitshiphu ngaphezu ekhemesti. Xa megacities udibana cheap "Anastrozole Kabi."

Kwincwadi yakhe, uGqr womngane G. De UPascal wabhala wathi: "Kucingelwa ukuba estrogen kwakheka ngenxa aromatization of testosterone okanye ezinye steroid kwiSebe le ngxenye kunye ingqondo, ukunciphisa secretion ka luteinizing hormone, kwaye, ngenxa yoko, imveliso testosterone." Gilman and Goodman waxelela ukuba ingxelo luvuliwe kunokuba zemali estrogen, kunokuba testosterone. Ngale ndlela, ucaciswe ukuba aromatase inhibitors unga nciphisa ngokubaluleka isiphumo inhibitory-arhente steroid ukwaba iihomoni sex lobuqu.

imiphumela emibi

I aromatase inhibitors ziyingozi abantu? Siyazi ukuba estrogen ngeedosi ephantsi zibe nempembelelo entle emzimbeni eyindoda. hormone estrogen ukwandisa nokurhafisa ukusebenza nobuntununtunu receptor androgen. Ngaphezu koko, bona ngokwabo zibe nefuthe zokuzikhusela steroid.

Meaning izihlunu estrogen receptor ochazwe kakuhle e Anna Wiik ngokweenkcukacha. Eneneni blocker ithamo omhle ngokwenene uya kusifaka ukunciphisa izinga estrogen, into leyo eyenza igalelo ukuvela iziphumo ebezingalindelekanga ezifana:

• inhibition wokukhula imisipha;
• ubuhlungu bamalunga (arthralgia);
• ukonakala ezempilo kunye ukuhla yobuntu;
• ukudana;
• ukuphazamiseka profile lipid igazi (ukunyuka cholesterol);
• ukuncipha ngamandla amathambo.

Subjectively, le mithi ukunyamezeleka ngaphezu "Tamoxifen".

zendalo inhibitor

Zezi zilandelayo:

• caffeine;
• resveratrol;
• zinc;
• nicotine;
• apigenin;
• catechins;
• eriodiktiol.

Ukusetyenziswa "Anastrozole"

Ngaphezu aromatase elungileyo inhibitors? la machiza ezisetyenziswa kakhulu abanxibe impahla. Umzekelo, "Anastrozole" ezifunekayo ukugcinwa kwamanzi emzimbeni womntu kunye nokuthintela isahlakalo gynecomastia (kaninzi kunye androgens testosterone kunye Dianabol uhlobo okanye zidityaniswe kunye finasteride). Kodwa kulo mzekelo, womdlali uba kunye nale entsonkothileyo onomtsalane iziyobisi balelwa ukusuka 'kuluhlu kwezinto ezivaliweyo kunye neendlela ", ngaphandle kokuba uluhlu yaso kwempembelelo engephi.

Ukusetyenziswa kwamalweyile ngendlela "Anastrozole" iimbaleki, nizithwala, ingakumbi, abanxibe impahla kunokubangela arthralgia, asthenia, okanye ukunciphisa ukuhamba amalungu, intloko ebuhlungu, somnolence. Kakade ke, maxa wambi kuvela iingxaki thromboembolic kunye nokuphuhlisa kwamalungu omzimba.

On "Anastrozole" Kuninzi kubhaliweyo kule ncwadi kwiimbaleki njengoko ichiza engeyongozi kakhulu. Kodwa imiphumela kude yaye ngoko nangoko xa zifunyanwa alo akucingeleki kakhulu kabuhlungu. Eneneni, ukuba kuphela athathe ipilisi enye (1 mg) yonke imihla, kunokuqulunqwa libizwe hormone kwakhula. Hi ndlela leyi, le meko uyaqapheleka ngaphezu kwe-80% yabantu abathe basebenzisa imveliso.

Ngokubanzi, inhibitors aromatase - amachiza eyaziwa ngokwaneleyo. odala blocker Iisampuli yesithathu "Anastrozole", yaye kamva "vorozole" yaye
'Letrozole', badalwa imveliso imigca yokuqala neyesibini ukuphiliswa saa receptor-HIV nomhlaza webele.

"Krizin"

Kuba weightlifters market amayeza ikwabonelela i-digidroksiflavon 5.7 ( "Krizin"), apho iimbaleki sebenzisa ngeedosi eziphezulu kakhulu. Kuye iipropati antiaromatazatnymi kwaye yaveliswa iifom ezimbini - MRM-Chrysin, zisetyenziswa 500 mg nganye philisi krizina engenazimpazamo kwaye SciFit-Chrysin ES, ukuze kuhlaliswe isiqingatha into esebenzayo.

iziphumo ebezingalindelekanga ababhekisi phambili abayityhilela, kodwa kufuneka ukhumbule ukuba zonke izinto kunye amalungiselelo nokuba antiaromatazatnym inyathelo, ekwaziyo ebangela umonakalo emzimbeni womdlali umxhelo. Ngaphezu koko, bona i "uLuhlu kwezinto akuvumelekanga kunye neendlela."

reviews

bodybuilders abaninzi bathi, esekelwe kumava nge "letrozole" ( "Femara"), baphetha: Le mveliso, ngokuthi yokusombulula ingxaki omnye (Isalathisi eliphezulu estrogen), ikhuthaza ukuvela nezinye iingxaki ezininzi. Kakade ke, aromatase inhibitors zibalulekile amadoda. Ngapha koko, umzimba (amadoda ingakumbi) isebenzisa estrogen ukulondoloza impilo amajoni omzimba, ingqondo, amanqanaba cholesterol eqhelekileyo, amalungu esempilweni, nemisipha, njalo-njalo.

Iimbaleki bathi estrogen ichukumisa indlela umzimba ngayo ukukhula kwezihlunu. Ukuthatha 2.5 mg "letrozole" ngemini beqala bazive ukulimala kakhulu amalungu articular kunye nemisipha, kwaye babe sesichengeni kwizifo ezosulelayo kunye wentsholongwane egazini.

Iimbaleki abaninzi bakholelwa ukuba 'Letrozole' ingasetyenziswa kuphela bodybuilders abaziingcali ukulungiselela gqatso. Ngenxa kuye, ukuba balahle ulwelo kwemfuneko emzimbeni (ukuba iingcali zempilo ngenxa koyisa ayikho buhlungu). Bayavuya ukuthabatha aromatase inhibitor. ixabiso yabo banelisekile.

Ezinye iimbaleki bathi ukusebenza 'Letrozole' HIV emzimbeni nokuba umthamo we 0.1-0.5 mg. Bathi ingxelo ukuba akukho kubi ngaphezu impembelelo minor ezinye inhibitors, kunye nomgangatho olu hlobo amayeza. Babanga ukuba subjectively, imveliso ngokukhawuleza buguqula wamatyhalarha volume kunokuba "Tamoxifen" yaye "Clomid". Kwakhona Bathi ukuba inhibitors aromatase - iziyobisi iindleko obagwebelayo umgangatho.

Abanye Ingxelo Iimbaleki ezinokuthi zisetyenziswe nayiphi blocker, kodwa ngenxa imveliso eliphezulu "letrozole" ngeedosi ezincinane, kuba yeyona ininzi.

"Anastrozole"

Namhlanje "Anastrozole" yeyona blocker kakhulu zithandwa. I ibiza ithathwa i "elalini." Ezinye inhibitors aromatase kwi ekhemesti zinqabile, umzekelo, "Anastrozole Kabi."

Abantu abaninzi akwawusindisa kwimpilo yabo ukhethe umgangatho.

Thatha "Anastrozole" ngokungqinelana nenqanaba yalo estradiol. Amanqanaba estradiol ngoko kuqala ivavanywe ukunyenyisa ngokusekelwe kuhlalutyo isabelo. Umyinge oyidlayo classical yi 0.5 mg ngosuku.

kweentsuku ezilishumi emva koko, kufuneka ukuba bahlolwe kwakhona. Ukuba inqanaba estradiol umgangatho, kunokwenzeka ukuba kuncitshiswe umthamo 0.5 mg kabini ngeveki. Ukuba nangoku phezulu, ulwamkelo kufuneka iqhubekeke. Kwaye ngoko ke kufuneka kusebenza de kumanqanaba estradiol bachache ngokupheleleyo.