Iipilisi ku xi "Fiziotenz": Iimpendulo ezigulane kunye amagqirha

iziyobisi umfutho olusebenzayo, a bakhethe imidazoline receptor agonist sisiyobisi "Fiziotenz". Baqinisekiswa bathi iindlela inceda ukunciphisa uxinzelelo seswekile kunye nabantu esinobunzima umzimba eliphezulu.

Iimpawu BP

Izifo iimpahla intliziyo negazi kuxhomekeke abantu abaninzi. Noko ke, amabhinqa la ezinxaxhileyo ukuphuhlisa kamva kunabesilisa. Kodwa kwenzeka lula luphawulwa amazinga aphezulu uxinzelelo lwegazi, iimpawu ezibuhlungu ucaca ngakumbi kakhulu ngakumbi. Lwegazi rhoqo eyenzeke nezinye izinto ezimbi: ukutyeba, isifo seswekile, ukuphazamiseka wesibindi, ukusilela kwezintso lipid ukutya.

Kunye ukwanda kobunzima bomzimba kwenzeka ukuphazamiseka SNA, owona nobangela uxinzelelo lwegazi kunye lwegazi Ukwakheka. hormone luvo eyabelwe kwangumqondiso igalelo luminal licuthe imithambo yegazi, ebangela entliziyweni ukunikezelwa oxygen ancedisana amalungu kufuneka ukutyhalela igazi ukuya torque phantsi koxinzelelo oluphezulu, ngaleyo ndlela lwegazi, oluhlasela indlela abaphathana amayeza. Omnye iziyobisi, sivumele nciphisa ubunzima obungakumbi, yindlela "Fiziotenz".

Isakhiwo kunye Nokuhlanganiselwa

medicament Iveliswe ngohlobo amacwecwe bhanya-camera. Izenzo eziphambili into esebenzayo moksonindin. Awona macandelo abancedisayo ziquka wemagniziyam stearate, crospovidone, povidone, monohydrate lactose.

iipropati kwemithi

Iziyobisi elikhutheleyo medicament na isenzo esembindini iqinile. Moxonidine eziseleni stem ubuchopho emane lukwakhuthaza receptors yovakalelo, aqukiweyo umthetho tonic reflex kunye nenkqubo lingaze luvo. Isiphumo ukuhla kumsebenzi kunye kwangumqondiso neuropathy ingcinezelo yodidi oluphezulu. izifundo ezininzi (placebo-control, kokuhlola, kabini-iimfama) zingqina impumelelo ichiza "Fiziotenz". Izimvo ezigulane kuqinisekisa ukuba ichiza yohlukile kwezinye izinto sympatholytic umfutho ukuba ungabi sisizekabani umlomo owomileyo, xa isetyenziswa akukho umthomalalisi.

Pharmacodynamics kunye Pharmacokinetics

Emva ukwamkelwa ngaphakathi uthetha-90 ekhulwini etsalwe kwinkqubo gastro-emathunjini. Le xi iphezulu into esebenzayo kwi plasma ngegazi iqatshelwe ngeyure. Isidlo phezu pharmacokinetics of moxonidine ayinasiphumo.

Le metabolite compound enkulu esebenzayo i dehydrogenated moxonidine kunye guanidine nezakhi. Half-ubomi moxonidine lwenzeka iiyure 2.5 nemini kwi-90% imveliso sakhi izintso amathumbu.

Xa izigulane lwegazi, xa kuthelekiswa nabantu esempilweni, utshintsho pharmacokinetics of moxonidine kwaqwalaselwa. Ukuxhasa kancinane ulawulo-kwikinetiki iparameters nga ilungiswe kubantu abalupheleyo lu dityanisiwe ukuhla moksodinina ngobunzulu ukutya, kwakunye bioavailability yayo ephezulu. Ngenxa yokunqongophala izifundo pharmacokinetic ayikhuthazwa ukusebenzisa iziyobisi ukuba izigulane ukuba ebudaleni.

Drug "Fiziotenz" Imiyalelo Sebenzisa

Baqinisekiswa bathi amacwecwe kufuneka kuthathwe ngomlomo, kungakhathaliseki ukuba ukutya. Ngokuqhelekileyo, ichiza ezisetyenziswa ngexesha idosi kokuqala ngemihla ka-200 mcg. Le mali iphezulu esinye neziyobisi ngaphezu 400 micrograms yonke imihla lahlulwe ngezinyuko ezimbini - 600 micrograms. Izigulane olungephi ukuya ukusilela intliziyo kakhulu abakhoyo wehemodialysis, kucetyiswa ukuba uthathe 200 micrograms usuku kuthetha. Nokunyamezelana mali zilungileyo ichiza ukuze kwandiswe kabini.

libanda

Ukuba ukusebenzisa ngokugqithisileyo iimpawu ezimbi ezahlukeneyo kungenzeka iziyobisi. Ngenxa yoko, amacwecwe "Fiziotenz" uxinzelelo (reviews iyiphakamisa) ukuqala yintloko, ukozela, umthomalalisi. Xa oyidlayo idlula uxinzelelo unokulahla kakhulu, ukuphuhlisa intlungu epigastric waphawula xerostomia, bradycardia, ukugabha, ukudinwa, ukwanda ukudinwa, ukuba nesiyezi. Ukongeza, izigulane akhathalele hyperglycemia, tachycardia, kunye nokwanda idlule uxinzelelo.

antidotes ezithile zenzelwe ukuba unyango iimpawu libanda. Ukuba hypotension kufuneka ufake dopamine nokwandisa isiqulatho fluid emzimbeni. Iimpawu bradycardia kunokwenzeka ukuba uyeke ukusebenzisa atropine. Xa libanda, ukunciphisa okanye ukuphelisa ngamazwi umfutho wegazi ekucetyiswa ukusetyenziswa bachasene Alpha-adrenoceptor.

imithi

Ukuhlanganiswa iziyobisi ayisoloko ukunika ukubaluleka ngenxa. Noko ke, xa efumana amachiza amabini okanye nangaphezulu inokuba buthathaka okanye nokuqiniswa izenzo efanayo. Kwimeko yokuqala, iyeza akayi ukunika isiphumo ekulindeleke, kule imeko yesibini, kukho ingozi yokuba i libanda, nkqu ityhefu.

Ngoko ke, xa kusetyenziswa amachiza umfutho (womchamo thiazide, blocker calcium imijelo ezicothayo) kunye medicament "Fiziotenz" (reviews zilumkisa malunga oku) ukuze aphuhlise isiphumo additive iqinile. unyango ngaxeshanye kunye yeQela tricyclic lihlisa ukusebenza amachiza protivopertenzivnyh engundoqo, kwaye akufunekanga ukuba isetyenziswe kunye ichiza "Fiziotenz".

Ukongeza, i-sixhobo likuvumela ukuba ukuphucula umsebenzi ngokwasengqondweni kwizigulane buthathaka ngokuthatha ichiza "Lorazepam". Isicelo kunye benzodiazepines kunokubangela umthomalalisi lekhamera. Ekuqeshweni iziyobisi 'digoxin "," glibenclamide "," hydrochlorothiazide "akukho ngxoxo pharmacokinetic.

Sebenzisa ngexesha lokukhulelwa

iziyobisi ezahlukeneyo kuchaphazela kakubi ndingekazalwa okanye umbungu, ephambili kwezinye iimeko ezimbi lo mntwana. Njengoko amalungu iziyobisi ezithathwe ubisi sikanina, uyakwazi kweyela umzimba kweentsana enze kuyo. Ngoko ke, ngethuba lokukhulelwa zisanyisa, kuyimfuneko ukuba uthathe amayeza okukhulu.

Ngaba Akukho ngaphandle - kwaye ichiza "Fiziotenz". ukuqeshwa kwakhe sisebenza kuphela emva kokubonisana oyingcali, kokuhlaziya ngenyameko ezinokuba luncedo unina kunye nobungozi umntwana. Ekubeni esisebenza ludlulele ubisi lwebele ngexesha ukondla usana bayinikele umva isicelo layo okanye uyeke ukuncancisa-lwebele.

izifundo zovavanyo olwenziwa kwizilwanyana, ifuthe ngqo okanye engangqalanga nesiyobisi ukukhulelwa, fetal (osandul ') okanye uphuhliso kokubeleka abangazange ezichongiweyo.

effect side

Kanye amayeza ezininzi, iipilisi "Fiziotenz" (ncomo zingqinele oku) ebangela yokusabela embi ivela emzimbeni. Oku kudla ngokwenzeka xa usebenzisa izixa ubuninzi ixesha elide kwaye hypersensitive ukuya isithako esebenzayo.

I-luvo yi ukusetyenziswa kweziyobisi ngayo intloko ebuhlungu, ukozela okanye ubuthongo, isiyezi. Ezi mpawu zibonakala kaninzi ngokwaneleyo. Ngomhla inxalenye yenkqubo sentliziyo olujikeleza abasabela elibi zenzeka kwiimeko ezinqabileyo, lubonakala nokwehla okukhulu koxinzelelo, hypotension intolerance. Ukongezelela, izigulane emva umlomo amava ulawulo owomileyo, isicaphucaphu, ukuba ugcinwe njenge reactions dermatologic angioedema, pruritus okanye angawokubhuda. Ukuba kukho isiphumo icala ichiza kufuneka ivingcwe, iimpawu ezimbi emva kweeveki ezintathu ukusetyenziswa, bakholisa ukuba shwaka. Noko ke, buza ingcali leyo kwakusafuneka.

Izimo

Akukho unyango "Fiziotenz" ingasiwa kuzo zonke iimeko. Izimvo oogqirha bathi kucetyiswa ukuba ukuthatha amayeza e:

• bradycardia (izinga intliziyo Me ibetha-50 ngomzuzu);
• SSS;
• malabsorption ilifa galactose nobandlululo (glucose)
• intswelo yelactose;
• anda ubuntununtunu kwicandelo iindlela;
• abantwana kanye abangaphantsi kweminyaka uninzi.

Ifundiwe imiqathango emiselweyo ichiza terminal kwisigaba okanye ukusilela kakhulu kwezintso, izigulane bangekhoyo wehemodialysis, xa ukusilela kakhulu esibindini.

Tablets "Fiziotenz": ezibonisa ukusetyenziswa, ncomo, imiyalelo ezizodwa

uphethwe Primary, apho oogqirha ukumisela imithi lwegazi. Kufuneka Makukhunjulwe ukuba ngexesha unyango kufuneka baphumeze esweni yenkqubo karhulumente wengcinezelo wegazi, ECG kunye nezinga intliziyo. Ukuba ufuna ukucima i amayeza, ngoko oku kufuneka kwenziwe kancinci.

Le lemveliso ngokungalunganga kuchaphazela ukukwazi ukuqhuba kunye neendlela zothutho. Nangona kunjalo, lo kuqulunqo "Fiziotenz" (testimonials isigulane zibonisa kuyo) kufuneka ukuba uthathe ngobulumko kuba kunokubangela isiyezi kunye ukozela. Oku kufuneka ingqalelo abantu abathatha inxaxheba ezinobungozi, efuna ukusoloko ingqalelo, imisebenzi.

iimeko Ukugcinwa, analogs nexabiso

Iipilisi kufuneka igcinwe kwindawo apho abantwana abakwazi ukufikelela. Ngokuxhomekeke kwimigaqo zokugcina (lobushushu ukuya ku 25 Degrees C, indawo emnyama eyomileyo) neziyobisi, akasayi kuphulukana iimpawu zazo amayeza, iminyaka emibini. Thenga amayeza "Fiziotenz" (reviews qinisekisa it) kunokwenzeka kwi kagqirha ezikhemisti. Price diphu iipilisi (0.2 mg) ngu 275 engange. Ukuba iyeza kwi ekhemesti ngenxa yesizathu esithile wayengekho, kuyimfuneko ukuba bajonge oontanga: "uCynthia," "Moksoniteks", "Moxonidine", "Moksogammu".

Izimvo elungiswa "Fiziotenz"

Izigulane ezininzi thetha ichiza njengendlela eyiyo esemgangathweni. Abantu bathi ukuthatha yona iminyaka, ichiza kwandisa uxinzelelo lwegazi okulungileyo, kungekho iziphumo ebezingalindelekanga. Abanye bathi iintsilelo amacwecwe kweendleko eziphezulu "Fiziotenz". Ukuphonononga kubonisa uphawulo elungileyo kunye nezinye iindlela amayeza unesifo.