"Estrozhel": imiyalelo zokusetyenziswa, inkcazo yokulungiselela, analogs, imiphumela emibi

Yinto akukho mfihlakalo ukuba esi sifo climacteric uphawuleka yawo-semithambo, yengqondo pathways ezidalwe ukuphazamiseka ukusuka ngesondo wamhle ezivelayo obudala involution lilonke ephilayo, kwakunye kwisiqalo ukuphela kancinane komsebenzi hormone ovarian.

Kweli xesha kunzima abafazi baziva rhoqo ukufikelwa ukuba, umzimba kunye neengalo intloko eliphezulu.

Ukongeza, iimpawu exesheni ziquka ucaphuka ngokugqithiseleyo, sokulibala, ukudakumba, ubuthathaka kunye imvakalelo bentshontsho. Ngokufuthi, sex wamhle litshintsha umphefumlo aphazamise migraine, vertigo, kwakunye ukuba ngokugqithiseleyo ukubila, nokudumba kunye vasospasm.

Ukudambisa imeko yomfazi, iinkampani zamachiza baqalisa ukuvelisa amachiza protivoklimaktericheskie. Eyona ngempumelelo ezi ziquka ezifana amayeza njenge "Estrozhel". Uphengululo (ngexesha exesheni na indlela emiswe rhoqo kakhulu) abasebenzisi ziya thaca ngezantsi. Kwakhona uya kufunda indlela yokusebenzisa ichiza wathi, wobeka phi kubiza, njalo-njalo.

Inkcazelo, ukwakheka, ezingxobeni ifomu release

wathengisa amayeza "Estrozhel" Ngayiphi indlela? Izimvo kwabasetyhini uxele ukuba ichiza anokufunyanwa ngokohlobo ijeli ye transdermal. Kuyinto enemibala, oluselubala, kwaye nevumba-ethanol.

Le esisebenza yale arhente izenzo estradiol. Njengoko izithako abangabancedani medicament iqulethe carbomer, ethanol, trolamine kunye namanzi okuhlamba.

Ukulungiselela "Estrozhel" (gel) kuthengiswa zohlobo lwe aluminiyam. Kukwafakwe kwakhona applicator ekhethekileyo ulungiselela.

features kwemithi

Yintoni na ijeli "Estrozhel"? Imiyalelo isicelo ibonisa ukuba i-arhente hormone, nto leyo yenza ngenxa yokunqongophala estrogen emzimbeni lomfazi.

Ngenxa izithako yalo eli yeza Umsebenzi estrogenic. It bujolise kuphela isicelo lwangaphandle okanye mlonyeni.

Xa unyango le fasilithi kwi-sex wamhle yehla kakhulu iimpawu syndrome ngxaki, kuqukwa ukudakumba, irhashalala, ukufikelwa kunye nokoma lobufazi.

Xa ukusebenza yayo kwezonyango unyango iimpawu postmenopausal amayeza ingqalelo engabumbeki unyango kunye nonyango estrogen ngomlomo. Ngaphezu koko, xa usebenzisa esi sixhobo xa izigulane ngxaki kwaphawula linyuke iinkqubo zokunciphisa lexinene ijwabu ithambo.

Kwakhona unyango wachitha inceda ukwehlisa cholesterol iyonke.

Asinako ukuba ichiza "Estrozhel", ixabiso yayo eboniswe ngezantsi, uye eyiyo procoagulant. Oku kunciphisa isixa antithrombin III kwaye yandisa hepatic Yindibanisela arhente igazi ekunqandeni K-oxhomekeke.

iipropati pharmacokinetic

Nokuba iyeza ako "Estrozhel"? Iingcali Ukubuyekezwa zithi emva kokuba isicelo enye yejeli kwenzeka ukuba ngumphunga kakhulu ngokukhawuleza ethanol, apho estradiol nangoko ingena esikhumbeni. Inxalenye enkulu ichiza kwangoko kuya yokujikeleza kwegazi, yaye ezincinane - igcinwe kwi nenqatha ongama, ekhutshwayo nayo kancinci.

Emva kokuba ukusetyenziswa basekuhlaleni yejeli ubuninzi lwee- estradiol egazini waphawula emva kwemizuzu 180-240. Le bioavailability beziyobisi yi-82%.

medicament kujongwa angabekwa ukuba isiphumo "yokupasa yokuqala", nto leyo inika plasma izinga estradiol xa kuthelekiswa ne-nucleoside ngomlomo.

Ukurhoxiswa estradiol kunye nokuguqulwa kwayo pathways efana naleyo kuba estrogen olufanayo zendalo.

Izinto ezibonisa ukuba isicelo se ukulungiselela lwangaphandle

Kuba yintoni iziyobisi injongo "Estrozhel" zingasetyenziswa? Imiyalelo yokusebenzisa zibonisa ukuba eli yeza Kucetyiswa ukunciphisa okanye ukuphelisa iimpawu onaso climacteric, kuquka ukuya exesheni okwenziwe wayenga. Ukongeza, ichiza ekuthethwa isoloko isetyenziswa lokhuseleko kunye nonyango kwamathambo ngexesha ukuya exesheni.

Izimo

Ingaba uyazi xa kufuneka usebenzise gel "Estrozhel"? Imiyalelo yokusebenzisa ingxelo ukuba ukuya Izimo elililo esi sixhobo ziquka iimeko oku kulandelayo:

• syndrome Rotor;
• kobuchopho okanye haemorrhagic ngesibetho;
• thrombophlebitis etsolo okanye thromboembolism;
• ngexesha lokukhulelwa;
• wesizalo ivuza igazi imvelaphi othile;
• ukusilela kwezintso;
• ibele;

• ; Johnson - syndrome yeeFom
• ezinezigulo estrogen-oxhomekeke okanye rhanelwa phambi kwabo;
• hypersensitivity;
• yamathumba ingozi okanye amabi, le yebhinqa;
• isifo esimandundu kwesibindi kwisigaba etsolo, nangezilonda isibindi senyongo.

ukusetyenziswa kakuhle medicament

na isicelo Xa gel "Estrozhel" ngononophelo obukhulu? Iingcali Guest ngale miqathango ilandelayo:

• leiomyoma;
• kwemithambo;
• endometriosis;
• ukuphazamiseka kwendlela umsebenzi wesibindi;
• pancreatitis;
• diabetes;
• migraine;
• sokuwa;
• somoya;
• hyperlipoproteinemia ekhaya;
• porphyria hepatic;
• isifo yokukrala uhlelo zokuzala kumntu wesini bubuhle;
• waphawula phambi senyongo, kuquka ukubonakala kwayo ngexa lokukhulelwa lokugqibela;
• trombozay, thrombophlebitis okanye thromboembolism (uthelekisa unyango estrogen);
• nomfutho kakhulu;
• pathology senyongo kunye cholelithiasis (imbali);
• hypercalcemia ezinxulumene metastases ithambo esiqwini webele in yamathumba;
• izifo kwegazi.

Gel "Estrozhel": imiyalelo yokusebenzisa

ukulungiselela kujongwa isetyenziswa ngokwemixholo kuphela. Kule meko usetyenziswa rhoqo okanye cyclically. Ubude unyango kunye umthamo ichiza zikhethiwe ngamnye.

Idosi enye yejeli "Estrozhel" (2.5 g) iqulethe 1.5 mg estradiol.

Xa unyango iimpawu exesheni eboniswe ezilahlwayo ngokusebenzisa ichiza ngosuku kwi imali idosi nganye. Ijeli le thinly batwabulule phezu eluswini kwingingqi kummandla empontshwa, ngesa-, emzimbeni okanye igxalaba, kwaye balindele sokufunxa yayo epheleleyo.

, Akayi kuba ngaphantsi kwe kummandla izandla zombini ogulayo site ulusu apho ichiza busetyenzisiwe.

Kuba ukusebenza oluchanekileyo izicelo result kakhulu ngempumelelo luphawulwa kukufakwa beziyobisi kwimizuzu-3. Ngelo xesha linye ukugcinwa stickiness emva kwesicelo se nedosi enye ye ichiza ukuba imizuzu emi-5 ibonisa kungekho ndawo esetyenziswa yi esikhumbeni.

Sebenzisa iyeza ukuba isigulane (kusasa okanye ngokuhlwa). Faka ijeli enqwenelekayo zezigqubuthelo icocwe ngaphambili.

imiphumela emibi

Zintoni iziphumo ezingafunwayo zenzeka emva ukusetyenziswa gel "Estrozhel"? Izimvo amabhinqa effects:

• ukuluma eluswini, isikhumba ukuthotywa, intloko ebuhlungu kunye uqaqanjelwa;
• kukutshintshatshintsha isimo, kunye nesiyezi;
• ubuntununtunu kunye nokwanda ubungakanani amadlala mammary, iintlungu zazo, menorrhagia, amenorrhea, ukuyila ukopha;
• yamathumba kwi namadlala mammary, ukwanda yobuntu, olubulala ukubhobhoza lobufazi, kuqukwa namathuba intermenstrual;
• ukuqunjelwa, inyongo isinyi isithintelo, isicaphucaphu, ukugabha, hepatitis, iintlungu epigastric, ukudla, pancreatitis;
• cholelithiasis, senyongo cholestatic, urhudo, amahlaba esiswini, ukuqumba;
• thromboembolism, qhagamshelana lens ukunganyamezelani, utshintsho ubunzima, nokudumba neuropathy;
• noxinzelelo lwegazi, negazi (kubandakanywa urticaria kunye ukurhawuzelela ulusu), qhagamshelana dermatitis.

Zonke ezi ziphumo bezingalindelekanga ichazwa kunokuba nguvumazonke. Ludla kwenzeka nisaqala unyango kunye phantse ungaze kufuna ukupheliswa amayeza.

iimpawu libanda

Kuza kwenzeka ntoni xa isixa esikhulu ichiza "Estrozhel" (ukuba isicelo njani esi sixhobo, sasinixelele ngasentla)? Kwimeko amathamo ngaphezulu medicament kwi isicaphucaphu nomonde ukugabha, kwakunye nokuphuhlisa zesibeleko ukopha. Xa ukuyilwa ezi mpawu sebenzisa ijeli ngoko nangoko.

Intsebenziswano kunye namanye amachiza

Ngaba kunokwenzeka ukudibanisa kunye namanye amachiza iziyobisi "Estrozhel" (gel)?

• Xa isicelo engumzekelo arhente umfutho kunye hypoglycemic, kunye anticoagulants kunganciphisa impumelelo yabo, nto leyo endinga indlela ngokutsha wolawulo ongaka.
• Indibaniso "Estrozhelya" kunye neziyobisi lipid-yandisa kukhokelela isiphumo bhetele indlela yokugqibela.
• Nge ukusetyenziswa ngaxeshanye kunye neziyobisi ezi inducers of microsomal enzyme zesibindi (umz: "rifamycins", "Carbamazepine", "griseofulvin" kunye barbiturates), plasma estradiol kunganciphisa.
• Ukusetyenziswa ijeli kunciphisa ukusebenza womchamo kunye iihomoni sex eyindoda.
• Ukusetyenziswa ngaxeshanye iziyobisi, analgesics opioid kwakunye namachiza asetyenziselwa zomzimba jikelele, ibalekisa yokucolwa of estradiol.
• Ukudityaniswa kunye nemithi ethile (kuquka "rifampicin" yaye "ampicillin"), kwakunye "phenylbutazone" kunciphisa plasma lamanani estradiol.
• unyango ngaxeshanye folic acid kunye ihomoni kwandisa neziphumo estradiol iindlela.

izincomo ezithile

"Estrozhel" ukusetyenziswa kweziyobisi kuyathintelwa ngexesha lokukhulelwa. Kufuneka kuqatshelwe ukuba phambi kokuba isicelo enye yejeli abasetyhini kufuneka uqiniseke ukuba uviwo epheleleyo yamanina. Nokusebenzisa ixesha elide ichiza, iinkqubo ezinjalo kufuneka kwenziwe ubuncinane kanye ngonyaka.

Ngokutsho kwizincomo unyango lweengcali yi advantageously wenziwe kunye estradiol, unyango progestin. Loo indibanisela uya kukhusela endometrium.

Kufuneka ukukhusela isifo of womntu obhinqileyo kunye ikuku, kwakunye kwesikhumba emabeleni zingangeni kubo ingqalelo iziyobisi.

ukusetyenziswa elide ichiza, kuquka amathamo eziphakamileyo, kwandisa umngcipheko webele kunye nomhlaza endometrial.

Ukuba ufuna elective utyando, uthomalaliso estrogen kufuneka ayekiswe iiveki 4-6 ngaphambili.

"Estrozhel" kufuneka zisetyenziswe ngexesha ucwangciso lokukhulelwa. Kufuneka kuqatshelwe ukuba medicament esebenzayo akuthethi zokuthintela iipropati kwaye akuthinteli ukukhulelwa.

Iziyobisi "Estrozhel" yaye "Utrozhestan" - udibaniso ogqibeleleyo. Ngenxa kule lungiselelo umgangatho wobomi yomguli ebudeni ukuya exesheni ngcono kakhulu.

Iindleko ezifana amalungiselelo

Yimalini gel "Estrozhel"? Ixabiso le-arhente imalunga 700 engange. Ukuba kuyimfuneko, oko indawo ngamanye amachiza afana "Estrokad", "Esterlan", "Estrovagin", "Ovestin", "Sinestrol", "Kolpotrofin", "ethinylestradiol", "Elvagin", "Ovipol Clio", "Pauzogest "," Klim "kunye nabanye.

Uhlaziya abafazi

I sex bubuhle usebenzisa yindlela kuba bhetele kwizigulo ngxaki, zimshiya impendulo kuphela HIV. Bakuphawula abanikaziyo ukusebenza yalo phezulu kunye rhoqo encinane nobukhali iziphumo ebezingalindelekanga kuthelekiswa kunye noogxa ngomlomo.

Ezinye iimpawu ezintle ichiza iquka indlela yayo lula wemithi, ukunqongophala tackiness emva kwenkqubo kunye kukufakwa ngokukhawuleza kwi esikhumbeni.