"Alimta" (pemetrexed): oothixo ixabiso. Apho ukuthenga Alimta engabizi?

"Alimta" (pemetrexed) - iziyobisi anticancer iluhlobo of a lyophilisate (lomgubo womisa ngendlela ekhethekileyo). Isetyenziswa ulungiselela isisombululo ibe nokubandakanywa efakwa.

Inkqubo igazi emva ithontsi, pemetrexed kuthunyelwa kwizisele apho polyglutamate fast iguqulwe ibe ifomu leyo bazondelele kule esiqwini ithumba, beqhekeza nabo kwiinkqubo pathways nasekunqandeni ukukhula kwabo.

Ngayo usebenza njani iindlela isihloko apho ichiza "Alimta" uthenge inzuzo, siya kuchaza kamva kweli nqaku.

Yintoni generic na, okanye ukuthenga Apho amayeza, "Alimta" kubiza

Bonisa, apho kunokwenzeka iziyobisi "Alimta" kuthenga atshiphu, kuyimfuneko ukuba izigulane ezininzi. Yinto eyaziwa ngokubanzi ukuba arhente anti-ithumba imali eninzi, yaye zichazwe kweli nqaku kungekho ngaphandle. Umzekelo, eMoscow, umzekelo, kwi lyophilisate ixabiso "Alimta" igcinwe kuluhlu evela engange 43 000 ukuya 74 000.

Ukuze uphephe inkcitho egqithisileyo, izigulane bafumane generics. Oku kuthetha, ekhutshwe phantsi mvume, kunye nokugcina engqongqo yobuchwepheshe, kwaye babe esisebenza efanayo njengoko brand-igama kweziyobisi. ixabiso yabo ayikho ngenxa yokuba kungekho ziphumo zinqwenelekayo, kunye nento yokuba ixabiso Ongayinikeliyo iindleko yophuhliso ukufezekiseka kwezi iziyobisi emarikeni.

WWW.ONKO24.COM Ngoko, kwisiza zingathengwa eveliswe yi Natco Pharma Ltd. in India wachaza izixhobo generic - Pemnat. iindleko zayo ziya kuba apha ukususela 18 000 engange. ibhotile, leyo, Kakade, Akubizi kakhulu kwaye ifikeleleke ngakumbi kubantu abazabalazela abanezifo ezimbi kakhulu nganye.

Ubungqina obubonakalayo buxela

unyango ngamachiza "Alimta" kufuneka wenziwe kuphela phantsi kweliso ingcali onolwazi esebenza izigulane ezinomhlaza. pemetrexed kulo uxilongo yamathumba amabi, imiphunga kunye bronchi, kwakunye ekufumanekeni mesothelioma pleural.

Izimo side effects

Contraindicated lyophilisate "Alimta" imfundiso le ecetywayo kwesi phepha, abasetyhini abakhulelweyo kunye phindeke, abantwana (njengoko ukusetyenziswa kwayo kwezi zigulane khange kufundwe), kwakunye nabo hypersensitivity ukuya ichiza.

Ngexesha unyango, iziphumo ebezingalindelekanga zilandelayo kwenzeka kwizigulane:

• ephula inkqubo hematopoietic - leukopenia, igazi, kunye neutropenia;
• isicaphucaphu, ukugabha;
• uphuhliso ukudla;
• nerhashalala yaye desquamation kwesikhumba;
• fatigue eliphezulu;
• sorhudo;
• uphuhliso pharyngitis.

Umthamo kunye nomthamo

"Alimta" iphathwa njenge ukumnika efakwa ngaphezu kwemizuzu eli-10.

Xa unyango yamathumba okubulalayo nonsmall umhlaza iseli wemiphunga le pleura kuyacetyiswa ukuba unyango lodidi lokuqala nodibaniso 'cisplatin ", elawulwa 500 mg / m² yonke imihla lokuqala zomjikelo weentsuku 21. Kule ithamo "Cisplatin" kufuneka ibe 75 mg / m² neziqhutywa ibe nokubandakanywa ilixa ngathi isiqingatha emva pemetrexed.

Xa kulawula yedwa kuphela 500 mg / m² wonke amalungiselelo wachaza umjikelo weentsuku ezili-21 zokuqala.

Indlela yokulungisa isisombululo

Njengoko isinyibilikisi for "Alimta" wasebenzisa iziyobisi NaCl (0.9% solution). Ukuze ufumane lyophilisate ogqityiweyo drug (100 mg) exutywe ne sodium chloride ukuya yoxinaniso-25 mg / ml. Emva koko ke igutyana obungenakuzanyazanyiswa nje, umphumo bekumele ukuba kucace gca, isisombululo enemibala. ukwahluka kuvumelekile of umbala walo emthubi okanye omthubi noluhlaza.

Isisombululo yahlaliswa sobisi ngakumbi kufuneka pemetrexed isisombululo sodium chloride ukufumana umthamo ml 100. A ngaphambi nolawulo kufuneka ahlolwe ukuze ubukho kwamasuntswana ezingenakunyibilika kunye nombala.

Ngokutsho eziqhotyoshelwe ichiza "Alimta" umyalelo ukusebenzisa le mali kufuneka abe kweeyure ezingama-24 emva kokupheka.