Lactulose: imiyalelo yokusebenzisa

Lactulose yi stereoisomer lactose zamntu kuhlelwe - iswekile ubisi. Njengokuba kuye, kwemolekyuli lactulose liquka elwa molecule fructose kunye galactose, kodwa ke uhlobo lwento alufumanekanga.

Lactulose, enyibilikayo powder emhlophe, kwafunyanwa kuqala ukusuka lactose ngo-1929, kodwa yayo kwezonyango zivuleleke kakhulu kamva. iziphumo zawo zaye kuqala ezichazwe kuphela iminyaka engamashumi amathathu. Okwangoku, iimveliso ezisekelwe le nto yenye kakhulu ngempumelelo nezaziwayo laxatives.

Lactulose, imiyalelo zokusetyenziswa apho inkcazelo eneenkcukacha iimpahla zazo, woba iklasi ka ekuthiwa-prebiotics - izinto ukuba ufake emzimbeni ukutya, kodwa hayi wendele kwaye phantsi kokudla. ixabiso yabo ixhomekeke kwinto yokuba ukukhuthaza ukukhula emathunjini of microflora iyingenelo, ukuthatha inxaxheba ukudla. Kulo - umahluko ophambili phakathi prebiotics ukuba laxatives ezininzi, enika amanyathelo afanelekileyo ngenxa umphumo kwizihlunu kakuhle emathunjini. Yokukhulisa isisu motility lactulose (isicelo User ichaza ukulungiselela wesenzo) kungenxa yokwanda yayo xi osmotic. A isitulo ngenxa yale nkqubo iba voluminous ngakumbi elulwelo, ihlabe kwenzeka isiqabu.

Ukongezelela isisu, lactulose kwandisa secretion ngayo ibile ducts, lukwakhuthaza isibindi kwaye ibhexesha iimpawu hepatic kunxilwe. Emva kokuba isicelo yayo kunciphisa kakhulu umthamo wegazi izinto eziyityhefu, ingakumbi ammonia. Ngokuqhelekileyo, ukuba bangabi yi iiseli zesibindi - hepatocytes. Nangona kunjalo, xa izigulane insufficiency hepatic, kwenzeka, umzekelo, isibindi ukuqina, metabolites inetyhefu kakhulu etsalwe ethunjini yaye kunempembelelo yityhefu kwi ebuchotsheni. Ngenxa yoko, le isiguli ezingapheliyo Encephalopathy portal systemic (PSE) - a esimbaxa neuro-izangoma syndrome. Lubonakala ngezidubedube neuromuscular, ukuphazamiseka yokuziphatha nokuphila. Lactulose (umsebenzisi ngolawulo zeziyobisi ibonisa oku) sesona siyobisi kakhulu, elikuvumela ukuba ukunciphisa imeko yomguli kwi PSE: inika kugqitywe olukhawulezayo ammonia emzimbeni kwaye uthintele kukufakwa yalo egazini.

Isenzo lactulose phezu microflora wamathumbu efanayo kwesiphumo fibre, ngokwesiko asetyenziselwa ukunyanga ukuqhina. Uphononongo lubonise ukuba ngenxa isicelo yayo ethunjini kunyusa kakhulu inani lactobacilli ababandakanyekayo ukwetyisa ukutya. Ukongeza, kusetyenziswa iintlobo-gingxi zamangenelela isisu: ukuncitshiswa kwenani iintsholongwane amathumbu yayintsholongwane eyosulela - enye iziphumo ichiza "Lactulose". ngokusebenzisa yesicelo incwadana ithi ukuba abangaphangeliyo ukuxhaphaka Salmonella kunye neearhente ze nokuxaxaza igazi - Shigella. Ngenxa yezi zakhiwo, lactulose isetyenziswa kunyango dysbiosis.

Ukuza kuthi ga ngoku, ihlabathi livelisa amashumi eziliqela ngamalungiselelo ngokwesiseko lactulose "Duphalac", "Normase", "Livolak", "Laktofiltrum", "Laktusan" kunye nabanye. Lactulose, imiyalelo zokusetyenziswa leyo ikuchaza ngokweenkcukacha iziphumo ebezingalindelekanga kunokwenzeka beziyobisi, i isisu kwenza efanelekileyo abantwana, abafazi abadala, abakhulelweyo kunye phindeke. Isebenza ecotha, ngobunono, phantse ngaphandle ubuhlungu. Phakathi iziphumo ebezingalindelekanga kunokwenzeka - iintlungu esiswini kunye ukuqunjelwa. Ngamanye amaxesha isicaphucaphu nokugabha ngokuqhelekileyo ezinxulumene nobuhlanga ngamnye ukuya ichiza. Kulo mzekelo, kuyimfuneko ukuba ayeke ulwamkelo.

Ikhosi ye unyango kunye lactulose, ngokwesilinganiso, kuba malunga neenyanga ezimbini. Kuba unyango lwe kwesisu lactulose (umsebenzisi sibonisa ngokuchanekileyo idosi Kunconywa) kuqala kwi ml 15-45 ngosuku (isikalo ayilungiswanga ngamnye). Kwathi kwiintsuku ezimbalwa ukuya idosi yesondlo - kuya kuba sisemi ngaphantsi. Babies isiraphu of lactulose (amanqaku umsebenzisi kuyo) kucetyiswa ukuba afumane ne nedosi ye-ml-5 ngosuku. Xa PSE ekuqaleni unyango, oko enyibilikayo emanzini kwaye ilawulwa rectally amaxesha 3-4 ngosuku. Emva nokuzinziswa isigulane ichiza sithathwa ngomlomo kwi idosi emiselwe ngugqirha.