Gamma-aminobutyric acid. Iimpawu ze intswelo emzimbeni

Eyona isilawuli ephambili yomzimba wethu - kuba ingqondo. Ngenxa kuye, elungelelanisiweyo isenzo zonke iinkqubo. siya Ungayihambisa, yabona, ukuva, ukuthetha, esiziva kunye baqonde Ngoncedo ingqondo kunye umnqonqo. Ngokuqhelekileyo, iinkqubo esembindini neuropathy luvo athwale isenzo sabo esebenzisa izakhiwo ezizodwa - neurotransmitters. Ezi ziquka inani kwezinto ezinceda nobuchopho okubonisa.

Isenzo neurotransmitters emzimbeni

Ukuze afeze ukosuleleka phakathi luvo, kwakunye izihlunu zomzimba abancedisi ezifunekayo. Ba ngabalamli, leyo ukuqhuba ngogesi lonke kwisithuba zobuchopho. La mandla abasendleleni kwalapho kunye, ngaphambi kokuba afike isiphelo, ebangela ukukhululwa neurotransmitter. "Abancedi" beyela umsantsa kwaye nefuthe kwi neuron eselumelwaneni, nto leyo iba akubonakali ukuya umqondiso. Ngaloo ndlela ethunyelwayo zonke pulses zombane emzimbeni. Neurotransmitters - into yokuba imvelaphi acid, kungabangela zombini excitation kunye inhibition kwinkqubo luvo. Zahlula-hlulwe ngamaqela ama-3: acid, peptides kunye catecholamines. Abameli kakhulu zixhaphakileyo epinephrine kunye norepinephrine, wesigrike-aminobutyric acid, glycine, dopamine, serotonin, glutamate, acetylcholine.

imisebenzi Gaba emzimbeni

Gamma-aminobutyric acid (IsiNgesi Gaba) inxulumene ngabalamli ukuba zinqanda luvo. Kuyinto into yemichiza ekhoyo abantu nezilwanyana. Gaba yenye asidi kubalulekile acid, ezo nako nokulungelelanisa iimolekyuli protein. Ngaphandle koku, ukubaluleka kwayo emzimbeni mkhulu kakhulu. Gamma-aminobutyric acid owenza imisebenzi ezimbini ezibalulekileyo:

1. isenzo Neurotransmitter. Ngenxa ukusebenza kwayo inhibitory ka Gaba abe iqinile, sine, iziphumo anticonvulsant. Ukongeza, oku kunegalelo ukukhuthazwa ubuthongo, ulawula umsebenzi iimoto, kuphucula iinkqubo kwinkumbulo nokucinga.
2. umsebenzi metabolic. Gaba kuphucula iinkqubo pathways ebuchotsheni negazi flow, iiseli zemithambo-luvo inika amandla. Ngenxa yale nto ke ikhutshwa phandle enye indlela ezinkulu - anti-hypoxic, okt ukuphepha oksijini yindlala. Okulandelayo yesenzo Gaba - ukususwa lweemveliso pathways emzimbeni kunye neziphumo kwi ukukhuthazwa kwimveliso hormone sokukhula yebhinqa sobuKristu.

Imithombo gamma-aminobutyric acid

Gaba yenye amacandelo igazi kunye nobuchopho esikule. Ngenxa yokungabikho loovimba yendalo kuyimfuneko ayizuze evela kweminye imithombo. Gamma-aminobutyric acid ekhoyo kwezinye iimveliso zezityalo. Ziquka iti nekofu amagqabi, ifungi filamentous, kwakunye incindi uhlobo lwezityalo cruciferous. Ukongeza, Gaba ilungisiwe ngendlela imichiza ngokusebenzisa iindlela ekuzakuqalwa. Ukuze uphuhliso wayo usebenzisa iintsholongwane yabantu ezifana E. coli. Kwezinye amayeza eziqulathe izinto ezisisiseko - nicotinoyl gamma-aminobutyric acid. Libhekisela analogs afunyenwe elabhoratri.

Iimpawu ukunqongophala Gaba emzimbeni

Xa ukungabikho gamma-aminobutyric acid, inani kweenkqubo zophendlo lwezifo. Ezona - amahlaba ukudakumba, ukuxhalaba, kunye kwezihlunu. It is ezinxulumene nemisebenzi kuncitshiswa eyenziwa kumzimba gamma-aminobutyric acid. Gaba kuyafuneka ukuba ukunika ingqondo namandla, ukulawula iinkqubo ezenzeka kuyo. Ngoko ke, xa ukuswela yayo iphuhlisa zizigulo ezininzi CNS. Ezi ziquka:

1. Cerebrovascular izifo - lwegazi, yegazi, ukufa icala kunye nentliziyo nokuhlaselwa.
2. Intloko, ubuthathaka, isiyezi, ukuphazamiseka kokulala, inkumbulo, ingqalelo.
3. Sokuwa.
4. isifo i-Alzheimer.
5. palsy.
6. Encephalopathy.
7. Ukwandisa izinga hormone okukhula.
8. Ukwehla kokusebenza umonakalo nokwenzakala ebuchotsheni.
9. isifo Parkinson kaThixo.
10. States depressive.
11. Hypoplasia kweenkqubo yengqondo ebantwaneni.
12. isimo Wayesoyika engqondweni uhayi.
13. Nolwandle kunye nokugula emoyeni.

Zonke ezi meko zifuna iyeza ukuzaliswa gamma-aminobutyric acid, kwakunye nokwanda ukusetyenziswa imveliso apho ikhoyo nokubakho.

Imithi eziqulathe Gaba

Ukuze kulungiswe le yokungabikho gamma-aminobutyric acid, funa iingcebiso zonyango. Yena uya kumisela therapy eyaneleyo replacement. Ubuncwane osisiseko onke amachiza - gamma-aminobutyric acid. Analogs iqulathe ongeziweyo ngohlobo ikhalsiyam, nicotinoyl, kwaye nezakhi ka Gaba. Amachiza eziphambili amayeza "Aminalon", "Pikamilon", "Phenibut", "Neyrobutal", "abantu neGabha:". Izinto ezibonisa ukuba ukusetyenziswa onke la machiza ukuphazamiseka kubangelwa kukungabikho gamma-aminobutyric acid emzimbeni. Imithi eziqulathe Gaba contraindicated abantwana abangaphantsi konyaka-1 abasetyhini abakhulelweyo (kwithuba leenyanga ezintathu yokuqala), hypersensitivity nezinto eziphambili okanye abangabancedani yaye ukusilela oyingozi kwezintso.

Gamma-aminobutyric acid: baqinisekiswa

Ekuqeshweni Gaba okanye analogue yayo izigulane yandiswe ngokubonakalayo imveliso ngempumelelo, ukulala kunye ulawulo kuvukwe, kukho ukuphucuka inkumbulo kunye nokuncitshiswa ithi edakumbisayo, wama yombono. Phakathi ziziphumo ebezingalindelekanga, ezinye izigulane ingxelo ukuqunjelwa, yobuntu linyukile, ukozela.