Calcium citrate: Uphawu, indlela yokusebenza, ukusetyenziswa

Isambuku Ca ngendlela umzimba omdala (malunga 99%) eziqulathwe esiqwini ithambo eyenziwa ziikristale hydroxyapatite. Xa serum ezincancisayo ezininzi, calcium xiyimiso imalunga 3 mmol / l (10-12 mg / 100 ml) kwaye rhoqo. okunzulu yemihla ngemihla constants musa ukudlula 3-5%. Ca kubalulekile ukuba eqhelekileyo yokusebenza luvo. Le neuromuscular leesynapse ion calcium ukukhuthaza ukukhutshwa acetylcholine kunye choline compound kunye receptor yayo, kwaye xa owenziwe cholinesterase acetylcholine excess - enzayimi hydrolyzes acetylcholine.

Ca ion ziqulethwe reticulum sarcoplasmic, kukhuthaza intsebenziswano phakathi actin kunye myosin, ngamanye ukuncitshiswa imicu kwezihlunu. Le isiphumo oluqhutywa phambi ion wemagniziyam.

ion calcium yenza iinkqubo enzymatic sikwinqanaba lokuqala igazi ekunqandeni - kukwenziwa thrombin kunye thromboplastin. Yokubopha of ion calcium kwi oxalate plasma okanye citrate kuthintela ekunqandeni igazi.

Kutsha nje kwaba indima ekhethekileyo icalcium kumsebenzi yeseli, apho kukho icytoplasm, eyavela ayidluli 10-6 nolovane. Kwinqanaba zeselula, kukho nokomzimba ezisisiseko ezintandathu ezixhomekeke uyondelelwano lwee- ion calcium:

a) Umsebenzi lwemoto weeseli (izihlunu nokuncipha);

b) lo excitability weseli ezinako ukujikelezisa electrostatic inyathelo amandla (kwezihlunu, nemithambo angxamele photoreception ucutheko intliziyo);

c) yokufumana izinto ukuba kuhlelwe esiseleni (secretion of hormone neurotransmitters);

g) ukufakwa kwezinto ezinyibilikayo kwi iseli ngo vesiculation (phagocytosis);

d) kukho ukutya intracellular (kuyondelelaniswe glucose, lipolysis, njl);

e) iseli ukuzala (mitosis kunye oocytes isichumiso, isidoda motility).

Ca ion kunye iiproteni ezithile zibonelela luthambe, nobulukhuni nethambo. amayeza Modern usebenzisa amalungiselelo amaninzi equlathe ion ikhalsiyam (glyukanat, citrate, chloride, zincancise, carbonate, phosphate, njalo njalo). Calcium citrate kubaluleke ngokukhethekileyo. Inqanaba ezingundoqo ukukhululwa calcium ukusuka yayo kwizakhiwo (phosphate, sulfates, kloride) kunye namacandelo eziphilayo nezimbiwa ukutya lwenzeka esiswini phantsi kwempembelelo chloride acid kunye nee-enzayim proteolytic. Asidi kunye phosphoric acid calcium ityuwa medium asidi esiswini na ubuhlobo, kwaye calcium ekwimo insimbi okanye ezintsonkothileyo kunye chelates ezinyibilikayo engena emathunjini amancinci. Ngoko ke, ngendlela secretory kuncitshiswa umsebenzi isisu nokufumaneka Ca sokufunxa asanelanga, kungaba yenye yezizathu intsilelo lwesi sakhi emzimbeni. Calcium citrate kungcono songanyibilikisswa bume asidi esiswini. calcium insimbi lula ingena inwebu zebhayoloji, nkqu umqobo ngumkhaya. Inxalenye enkulu (malunga nama-80%) ze calcium kwazona endleni, umchamo we malunga ne-20%. Ngenxa calcium citrate ityuwa kunokuba citrate ikhuthaza ukuncitshiswa kwe oxalate kwi umchamo, ukusetyenziswa kweziyobisi akazange ukuba ukhokelele ekubeni kusekwe ngamatye zezintso.

Kufumaniseka ukuba ebudeni bobusuku iyasebenza ukhetho iityuwa izimbiwa emzimbeni. Ngenxa yokuba oogqirha Sicebisa uthatha calcium citrate emva kwemini okanye ngokuhlwa. Kwaba nobuhlobo ezimbi correlative phakathi ithamo yokulungiselela calcium kunye nomsebenzi amayeza. Kuthetha ukuthini? calcium citrate ako ngcono ngumzimba ngeedosi ezincinane. Ngoko ke kungcono ukuthatha amachiza izihlandlo eziliqela ngemini. Kwiqela lobudala ngalinye elisekiweyo imiqathango ukusetyenziswa calcium nokomzimba. Calcium emiselweyo njenge lokuthintela nezinyangayo (yamathambo, kwamathambo, osteomalacia, ngokuba ekomelezeni wayesebenzisa amazinyo) njongo. Ipotaziyam citrate omiselwe ukusilela intliziyo, lwegazi, kuqheleke esiti-isiseko kunye nokulungelelana amanzi netyuwa emzimbeni.